An observational study in Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 and Spinocerebellar Ataxia Type 3, sponsored by University of Chicago. Completed at 5 sites in United States. Open to participants aged 12 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-05.
Sponsored by University of Chicago · Observational
This research study is testing body-worn sensors to measure movement during simple tests of coordination, in order to evaluate the progression and severity of ataxia.
111 studies on the registry are indexed under Spinocerebellar Ataxias; 27 are open to participants now.
This study's enrollment of 128 is close to the median of 124 across 32 observational studies indexed under Spinocerebellar Ataxias.
Browse Spinocerebellar Ataxias studies →University of Chicago is the lead sponsor of 924 studies on the registry; 185 are open to participants now.
Of its 102 completed or terminated interventional studies of FDA-regulated products, 71 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
ataxia clinics
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Exclusion Criteria:
individuals with a genetically confirmed diagnosis of SCA-1
individuals with a genetically confirmed diagnosis of SCA-2
individuals with a genetically confirmed diagnosis of SCA-3
individuals with a genetically confirmed diagnosis of SCA-6
individuals with a genetically confirmed diagnosis of FA
Healthy, age-matched controls
Healthy, age-matched controls
iSARA
measurements collected by wearable inertial sensors during instrumented Scale for the Assessment and Rating of Ataxia (iSARA)
Time frame: 2 years
SARA
Scale for the Assessment and Rating of Ataxia (SARA) measurements evaluated by clinician to measure severity of spinocerebellar ataxia through coordination, speech, stance, and gait
Time frame: 2 years
mFARS
modified Friedreich's Ataxia Rating Scale (mFARS) measurements evaluated by clinician compared to measure severity of Friedreich's ataxia through coordination, speech, stance, and gait
Time frame: 2 years
Daily Life (UChicago site ONLY)
APDM SmartSox technology used to measure daily life activity(movement, falls, etc.) of all University of Chicago subjects
Time frame: 2 weeks
Ataxia App on Watch/iPhone
Bi-weekly assessments completed on Ataxia Application for Apple Watches and iPhones. Data collected includes active monitoring of speech, stance, coordination, gait and patient-reported symptoms.
Time frame: 2 years
Patient-Reported Questionnaires of Health
Activities, Balance, and Confidence (ABC) Questionnaire; EQ-5D-5L Health Questionnaire; Modified Fatigue Impact Scale (MFIS-5); Activities of Daily Living (ADLs)
Time frame: 2 years
Falls Questionnaire
Automatic email sent out to subjects inquiring about any falls and near falls they have experienced during the past month
Time frame: 2 years
Functional Staging
Clinician evaluates severity of ataxia symptoms.
Time frame: 2 years
Timed 25 Foot Walk
Subjects walk for 25 feet, as quickly and safely as possible, while being timed
Time frame: 2 years
Plan to share: No
No publications or documents are linked to this record.
Ran from Jun 2019 to primary completion in Apr 2024, 58 months.
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This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.
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