Lymphatic Abnormalities clinical trials
The registry lists 41 studies for Lymphatic Abnormalities across more than 10 countries. 18 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-21.
Status
- Completed
- 18
- Recruiting
- 16
- Not yet recruiting
- 2
- Terminated
- 2
- Withdrawn
- 1
- Status unknown
- 1
Phase
- Phase 2
- 16
- Phase 3
- 5
- Phase 1
- 4
- Phase 4
- 2
Where
- United States
- 18
- China
- 6
- France
- 5
- Australia
- 3
- Italy
- 3
- Germany
- 3
Who runs them
West China Hospital (3) · University of Arkansas (2) · Palvella Therapeutics, Inc. (2) · Nanjing Children's Hospital (2) · University of Aarhus (2) · Stanford University (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Protara Therapeutics (1)
Studies
Recruiting first, then most recently updated. Showing 41 of 41 — search for more.
- A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES SyndromeRecruitingNCT07285005Phase 33 countries
- Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.RecruitingNCT05948943Phase 2/312 countries
- Lymphatic Anomalies Registry for the Assessment of Outcome DataRecruitingNCT023995271 country
- A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)RecruitingNCT06789913Phase 29 countries
- Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of AgeRecruitingNCT05871970Phase 21 country
- A Prospective Natural History Study of Lymphatic AnomaliesRecruitingNCT057311411 country
- Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic MalformationsRecruitingNCT03243019Phase 21 country
- A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular MalformationsRecruitingNCT05983159Phase 21 country
- Weekly Sirolimus TherapyRecruitingNCT04861064Phase 21 country
- A Prospective Study on the Treatment of cLM Based on ICG ImagingRecruitingNCT06275022Not applicable1 country
- European Registry Study on Lymphatic InterventionsRecruitingNCT071312931 country
- Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic MalformationsNot yet recruitingNCT07320001Phase 2
- Diagnostic Imaging of Vascular Malformations Using MSOT and ULMNot yet recruitingNCT069942601 country
- Institution of an Italian Registry and Biobank for Biological Sample CollectionRecruitingNCT06892964Not applicable1 country
- Different Doses of Sirolimus for the Treatment of Cystic Lymphatic MalformationsRecruitingNCT06673290Phase 2/31 country
- Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric PatientsRecruitingNCT06437158Phase 21 country
- Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular AnomaliesRecruitingNCT04921722Phase 41 country
- Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular MalformationsRecruitingNCT061607391 country
- Apple Peptide Complex for Post-Surgical and Aesthetic Skin RecoveryCompletedNCT07807085Not applicable1 country
- Intralesional Bleomycin Sclerotherapy for Low-Flow Vascular Malformations of the Head and NeckCompletedNCT07728825Phase 41 country
- Bleomycin Intralesional Injections of Cystic HygromasCompletedNCT07189832Not applicable1 country
- SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic MalformationsActive, not recruitingNCT06239480Phase 31 country
- National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS)CompletedNCT055638311 country
- Topical Sirolimus in Cutaneous Lymphatic MalformationsCompletedNCT03972592Phase 21 country
- Bleomycin as an Effective and Curative Adjunct Therapy for LymphangiomaCompletedNCT069437031 country
- Indocyanine Green Lymphography in Management of Lingual Lymphatic MalformationCompletedNCT06755905Not applicable1 country
- Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic MalformationsCompletedNCT05050149Phase 21 country
- Clinical Characteristics of Lymphatic MalformationsCompletedNCT062577191 country
- Lymphatic Function in Patients With Fontan Circulation: Effect of Physical TrainingCompletedNCT05934578Not applicable1 country
- Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT02335242Phase 21 country
- First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene MutationsTerminatedNCT04409145Phase 1/21 country
- Vascular Anomaly Pathology and Genomics Biopsy StudyCompletedNCT04836884Not applicable1 country
- A Pharmacokinetic, Pharmacodynamic, Safety and Tolerability Study of CERC-006 in Adults With Complex Lymphatic MalformationsWithdrawnNCT04994002Phase 11 country
- OK432 (Picibanil) in the Treatment of Lymphatic MalformationsCompletedNCT03427619Phase 21 country
- Lymphatic Function in Patients With a Fontan Circulation From BrazilCompletedNCT043945071 country
- Airway Vascular LesionsCompletedNCT00866827
- Lymphatic Function in Patients With a Fontan-Kreutzer CirculationStatus unknownNCT03379805
- A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT01290484Phase 1/21 country
- Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic MalformationsCompletedNCT00010452Phase 2/31 country
- Selenium in the Treatment of Complicated Lymphatic MalformationsTerminatedNCT01212965Phase 11 country
- Diagnosis of Hemangiomas and Vascular MalformationsCompletedNCT00577213