An observational study in Lymphatic Malformation and Lymphangioma, sponsored by West China Hospital. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2024-02-14.
Sponsored by West China Hospital · Observational
The primary purpose of this study is to retrospectively identify the clinical characteristics of abdominal lymphatic malformations (ALMs) in our single center in China. The second objective of this study is to retrospectively compare the epidemiological features, clinical presentations, cyst properties, surgical treatments, and risk factors for preoperative complications of ALMs between paediatric participants and adult participants.
Lymphatic malformations (LMs) are vascular anomalies that arise from abnormal embryonic development of the lymphatic system and can present as dilated lymphatic channels or cysts lined by lymphatic endothelial cells. Abdominal lymphatic malformations (ALMs) are rare entities that account for fewer than 10% of LMs and may occur not only in the tissues or organs in the abdominal cavity, such as the mesentery, spleen and pancreas but also in the retroperitoneal space. ALMs can manifest as an infection, chronic abdominal discomfort, acute abdomen, or fatal disease.
42 studies on the registry are indexed under Lymphatic Abnormalities; 17 are open to participants now.
This study's enrollment of 320 is above the median of 56 across 13 observational studies indexed under Lymphatic Abnormalities.
Browse Lymphatic Abnormalities studies →West China Hospital is the lead sponsor of 501 studies on the registry; 246 are open to participants now.
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In this study, The investigators retrospectively collected and compared the data related to the preoperative information, intraoperative findings and postoperative pathological analysis of the enrolled abdominal lymphatic malformations for paediatric and adult participants.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
Histologically or cytologically confirmed
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The investigators defined participants under 14 years old as the paediatric group.
Other: Compare the epidemiological characteristics, clinical presentations, surgical treatments and risk factors for preoperative complications of ALMs between paediatric and adult participants.
The investigators defined participants over 14 years old as the adult group.
Other: Compare the epidemiological characteristics, clinical presentations, surgical treatments and risk factors for preoperative complications of ALMs between paediatric and adult participants.
Compare the epidemiological characteristics, clinical presentations, surgical treatments and risk factors for preoperative complications of ALMs between paediatric and adult participants.
The location of abdominal lymphatic malformations in participants
Location included mesentery, retroperitoneum, omentum, spleen, etc.
Time frame: From 2009.1 to 2022.12
The morphologic subtypes of abdominal lymphatic malformations in participants
Morphologic subtypes included macrocystic, microcystic and mixed type.
Time frame: From 2009.1 to 2022.12
The presentations at diagnosis of abdominal lymphatic malformations in participants
Presentations at diagnosis included chronic pain, acute abdominal disease and incidental health checkup.
Time frame: From 2009.1 to 2022.12
The largest diameter of abdominal lymphatic malformations in participants
Largest diameter in centimeters was mainly measured by intraoperative detections.
Time frame: From 2009.1 to 2022.12
The preoperative complications of abdominal lymphatic malformations in participants
Preoperative complications included intestinal volvulus, haemorrhage, infection, rupture and compression.
Time frame: From 2009.1 to 2022.12
The incidence of abdominal lymphatic malformations in paediatric and adult group
Incidence of abdominal lymphatic malformations in paediatric and adult group was retrospectively compared.
Time frame: From 2009.1 to 2022.12
The number of female patients with abdominal lymphatic malformations in paediatric and adult group
Number of female patients with abdominal lymphatic malformations in paediatric and adult group was retrospectively compared.
Time frame: From 2009.1 to 2022.12
The rate of abdominal lymphatic malformations with acute abdomen in paediatric and adult group
Rate of abdominal lymphatic malformations with acute abdomen in paediatric and adult group was retrospectively compared.
Time frame: From 2009.1 to 2022.12
The rate of abdominal lymphatic malformations located in mesentery for paediatric and adult group
Rate of abdominal lymphatic malformations located in mesentery for paediatric and adult group was retrospectively compared.
Time frame: From 2009.1 to 2022.12
The risk factors of preoperative complications of abdominal lymphatic malformations for paediatric and adult group.
Risk factors of preoperative complications of abdominal lymphatic malformations for paediatric and adult group was retrospectively compared.
Time frame: From 2009.1 to 2022.12
Plan to share: No
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This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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