Lichen Sclerosus et Atrophicus clinical trials
The registry lists 30 studies for Lichen Sclerosus et Atrophicus across more than 10 countries. 8 are recruiting or about to start. 20 of them are mainly about Lichen Sclerosus et Atrophicus (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-13.
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Who runs them
Center for Vulvovaginal Disorders (5) · Northwestern University (2) · University of Zurich (1) · Stratpharma AG (1) · Ruhr University of Bochum (1) · Region Västerbotten (1) · Medical University of Graz (1) · 1st Federal Budgetary Healthcare Institution Volga District Medical Center (1)
What is being tested here
Drugs under test in Lichen Sclerosus et Atrophicus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nemolizumab | 1 | 0 | 1 |
| Delgocitinib | 1 | 1 | 1 |
| Clobetasol | 0 | 1 | 2 |
| Platelet rich plasma | 0 | 0 | 2 |
| Ruxolitinib | 0 | 0 | 1 |
| Pimecrolimus | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Identification of Genetic Variants Associated With Lichen Sclerosus · Gudula Kirtschig
- May 2027Vaginal Ecosystem and Network in the United States Study · Vaginal Biome Science
- Jul 2027Laser Treatment for Lichen Sclerosus · Sciton
- Sep 2027Nemolizumab for LS · University of Texas Southwestern Medical Center
- Nov 2027Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus · Kantonsspital Winterthur KSW
Who these studies take
Of the 5 Lichen Sclerosus et Atrophicus studies recruiting now, 5 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (20%) take children under 18. 2 (40%) are for women only and 1 (20%) for men only; 3 (60%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (20%) | 1 (20%) |
| 18 | 4 (80%) | 3 (60%) |
| 30 | 4 (80%) | 3 (60%) |
| 40 | 4 (80%) | 3 (60%) |
| 50 | 4 (80%) | 3 (60%) |
| 65 | 4 (80%) | 3 (60%) |
| 75 | 4 (80%) | 3 (60%) |
| 85 | 4 (80%) | 3 (60%) |
Across all 30 studies, recruiting or not: 7% stop at 75 or younger and 0% at 65; 13% take children; 83% are for women only and 3% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 30 of 30. search them.
- A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen SclerosusRecruitingNCT07335588Phase 33 countries
- Identification of Genetic Variants Associated With Lichen SclerosusRecruitingNCT077208301 country
- Nemolizumab for LSNot yet recruitingNCT07704775Phase 21 country
- Laser Treatment for Lichen SclerosusRecruitingNCT06389071Not applicable1 country
- Efficacy of Collagendep in Reducing Vulvar Dryness in Patients With Lichen Sclerosus Treated With Fat GraftingNot yet recruitingNCT07450625Not applicable
- Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of LifeRecruitingNCT069842631 country
- Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen SclerosusRecruitingNCT06135402Not applicable1 country
- Vaginal Ecosystem and Network in the United States StudyEnrolling by invitationNCT064727652 countries
- Topical Ruxolitinib Evaluation in Immune-related Vitiligo-like DepigmentationActive, not recruitingNCT07725432Phase 21 country
- Laser vs Clobetasol for Lichen SclerosusCompletedNCT05010421Phase 31 country
- Laser Therapy in Women With Lichenoid DisordersCompletedNCT04697563Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen SclerosusCompletedNCT05593445Phase 22 countries
- Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile MicrobiomeStatus unknownNCT056712631 country
- a Flexible Wound Dressing for the Management of Genital Skin ConditionsCompletedNCT05396261Not applicable1 country
- Efficacy and Safety of the Neodymium Laser in Treatment of Urogenital Tract Diseases in WomenCompletedNCT052512201 country
- Clobetasol Propionate Versus Fractionated Carbon Dioxide Laser for the Treatment of Lichen SclerosusCompletedNCT02573883Phase 31 country
- Effect of Treatment With the Ablative Fractional Carbodioxide Laser in Vulvar Lichen SclerosisStatus unknownNCT04107454Not applicable1 country
- MonaLisa Touch Laser for the Treatment of Vulvar Lichen SclerosusCompletedNCT03665584Not applicable1 country
- Vulvar Mucosal Specialty Clinic Chart ReviewTerminatedNCT028812291 country
- Vulvar Scarring Grading Scale for Lichen SclerosusTerminatedNCT028809041 country
- Lichen Sclerosus - the Influence on Quality of LifeCompletedNCT03419377Not applicable1 country
- Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar DermatosisCompletedNCT02732145Not applicable1 country
- Safety and Efficacy of Laser Therapy in GynaecologyStatus unknownNCT040730821 country
- Fractional / Pixel CO2 Laser Treatment of Vulvar Atrophy and Lichen SclerosusCompletedNCT03063684Not applicable1 country
- Platelet Rich Plasma (PRP) for Vulvar Lichen SclerosusCompletedNCT03045172Not applicable1 country
- Biomarkers of Lichen SclerosusStatus unknownNCT035614281 country
- Nd:Yttrium Aluminum Garnet Laser Treatment for Lichen SclerosusStatus unknownNCT03525522Not applicable
- Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseSuspendedNCT022239751 country
- Platelet Rich Plasma Injections for Vulvar Lichen SclerosusCompletedNCT02794363Not applicable
- Clobetasol Versus Pimecrolimus for Vulvar Lichen SclerosusCompletedNCT00393263Phase 21 country