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Li-Fraumeni Syndrome clinical trials

The registry lists 25 studies for Li-Fraumeni Syndrome across more than 10 countries. 16 are recruiting or about to start. 17 of them are mainly about Li-Fraumeni Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.

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Status

Recruiting
13
Completed
8
Not yet recruiting
2
Enrolling by invitation
1
Active, not recruiting
1

Phase

Phase 2
1
Phase 3
1
Phase 1
1

Where

United States
14
United Kingdom
4
Canada
3
France
2
China
1
Korea, Republic of
1

Who runs them

National Cancer Institute (NCI) (5) · Royal Marsden NHS Foundation Trust (2) · Gustave Roussy, Cancer Campus, Grand Paris (2) · Dana-Farber Cancer Institute (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · M.D. Anderson Cancer Center (1) · Yang Li (1) · The Hospital for Sick Children (1)

Coming up

0phase 3 studies under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 13 Li-Fraumeni Syndrome studies recruiting now, 9 (69%) set no upper age limit and 1 (8%) stop at 75 or younger. 9 (69%) take children under 18. 1 (8%) are for women only and 0 (0%) for men only; 5 (38%) take healthy volunteers.

Recruiting studies that take each age, of 13
AgeWomenMen
109 (69%)9 (69%)
1813 (100%)12 (92%)
3012 (92%)11 (85%)
4012 (92%)11 (85%)
5012 (92%)11 (85%)
6512 (92%)11 (85%)
7512 (92%)11 (85%)
8512 (92%)11 (85%)

Across all 25 studies, recruiting or not: 20% stop at 75 or younger and 16% at 65; 56% take children; 4% are for women only and 0% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 15, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 25 of 25. search them.