Intestinal Neoplasms clinical trials
The registry lists 110 studies for Intestinal Neoplasms across more than 10 countries. 25 are recruiting or about to start. 29 of them are mainly about Intestinal Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 12 narrower conditions too, such as Colorectal Neoplasms: 10,212 studies, 2,716 open.
Get an email when these change. Save the Intestinal Neoplasms studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Exact Sciences Corporation (6) · RenJi Hospital (5) · Isofol Medical AB (3) · Royal Marsden NHS Foundation Trust (3) · Revolution Medicines, Inc. (3) · Magentiq Eye LTD (2) · South Tyneside and Sunderland NHS Foundation Trust (2) · Fudan University (2)
What is being tested here
Drugs under test in Intestinal Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Artesunate | 2 | 0 | 2 |
| Daraxonrasib | 2 | 0 | 2 |
| Irinotecan | 1 | 2 | 2 |
| Elironrasib | 1 | 0 | 2 |
| Bevacizumab | 1 | 2 | 2 |
| Anti-PD-1/Anti-VEGF Bispecific Antibody PF-08634404 | 1 | 1 | 1 |
| Repotrectinib | 1 | 0 | 1 |
| SGM-101 | 1 | 0 | 1 |
| Ciprofol | 1 | 0 | 1 |
| Fluorouracil | 0 | 1 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open · Immune checkpoint inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8, phase 3 first
- Dec 2026A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC · Phase 3 · Sun Yat-sen University
- Jan 2027SL-28 for Advanced Solid Tumours · Second Life Therapeutics
- Feb 2027EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults · University of Sunderland
- Mar 2027Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors · Revolution Medicines, Inc.
- Apr 2027Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal · University of Edinburgh
- May 2027Understanding New Cachexia Subtypes Through Observational Epidemiological Research · Kaiser Permanente
- May 2027Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS · Revolution Medicines, Inc.
- Oct 2027A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers · Novartis Pharmaceuticals
Who these studies take
Of the 18 Intestinal Neoplasms studies recruiting now, 13 (72%) set no upper age limit and 2 (11%) stop at 75 or younger. 2 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (6%) | 1 (6%) |
| 18 | 17 (94%) | 17 (94%) |
| 30 | 17 (94%) | 17 (94%) |
| 40 | 17 (94%) | 17 (94%) |
| 50 | 18 (100%) | 18 (100%) |
| 65 | 17 (94%) | 17 (94%) |
| 75 | 17 (94%) | 17 (94%) |
| 85 | 14 (78%) | 14 (78%) |
Across all 110 studies, recruiting or not: 15% stop at 75 or younger and 4% at 65; 7% take children; 1% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Intestinal Neoplasms studies take
Of 17 observational studies under Intestinal Neoplasms, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo11–26 · 13 studies | — | — |
| Observational | 33 mo24–78 · 17 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 110. Browse all 110 → or search them.
- NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal CancersRecruitingNCT07060014Phase 11 country
- Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal CancerRecruitingNCT07222800Phase 317 countries
- Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsRecruitingNCT06128551Phase 1/27 countries
- SL-28 for Advanced Solid TumoursRecruitingNCT07341737Phase 1/21 country
- Use of a Novel Camera to Check the Bowel After Polyp or Tumour RemovalNot yet recruitingNCT073411261 country
- The Effect of Ostomy Care Education Applied With the Teach-Back Method to Ostomy-Opened Individuals on Self-Care Power, Ostomy Adjustment, and AnxietyRecruitingNCT077880791 country
- Understanding New Cachexia Subtypes Through Observational Epidemiological ResearchRecruitingNCT077763531 country
- A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRCRecruitingNCT03303495Phase 31 country
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/219 countries
- Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RASRecruitingNCT05379985Phase 1/21 country
- The Food Environment, Microbial Cysteine Metabolism, and Cancer DisparitiesRecruitingNCT07086833Not applicable1 country
- Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal CancerNot yet recruitingNCT07095309Phase 21 country
- Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Intestinal CarcinomaNot yet recruitingNCT069798821 country
- EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black AdultsNot yet recruitingNCT06981182Not applicable1 country
- TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal CancerRecruitingNCT05646511Phase 31 country
- Study to Evaluate the Diagnostic Performance of of MAGENTIQ-COLO During Colonoscopy.Not yet recruitingNCT06568523Not applicable3 countries
- Assessing Frailty and Its Impacts on Patients Facing Major GI SurgeryRecruitingNCT062673781 country
- SGM-101 in Colorectal Brain Metastases.RecruitingNCT04755920Phase 21 country
- Capsule Endoscopy in Iron Deficiency AnaemiaNot yet recruitingNCT062193951 country
- Evaluation of Intestinal Parasites in Patients With Intestinal Cancer in Sohag, Egypt.RecruitingNCT058508841 country
- PARP Inhibitor CVL218 in Combination Therapy for Patients With Advanced Solid TumorsNot yet recruitingNCT06078670Phase 1/2
- Dose Exploration of Ciprofol for Sedation in Gastrointestinal Endoscopic Diagnosis and Treatment of Obese Patients.RecruitingNCT05517408Not applicable1 country
- Postoperative Effects of Different Enterostomy ApproachesRecruitingNCT05853094Not applicable1 country
- Spanish Series of Patients Treated With the Radionuclide Lutetium177RecruitingNCT049492821 country
- A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal CancerRecruitingNCT02633098Phase 21 country
- CRC Detection Reliable Assessment With BloodActive, not recruitingNCT055510521 country
- A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal CancerActive, not recruitingNCT04607421Phase 329 countries
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 112 countries
- Improving Muslim Women's Uptake of Cancer Screening (IMCAN)CompletedNCT06106165Not applicable1 country
- Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsActive, not recruitingNCT05462717Phase 113 countries
- Drainage After Rectal Excision for Rectal CancerCompletedNCT01269567Phase 31 country
- A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node MetastasisCompletedNCT06048146Not applicable1 country
- Capsule Endoscopy Delivery at sCale Through Enhanced AI anaLysis StudyCompletedNCT060088471 country
- Effects of HIPEC on Postoperative Bowel Motility and ComplicationsActive, not recruitingNCT073531771 country
- Comparison of Scoring Systems in Gastrointestinal Cancer SurgeryCompletedNCT073256561 country
- Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)CompletedNCT037715081 country
- Observational Study of Early Contact With Palliative Care Unit for Patients Receiving First Line Palliative Chemotherapy With Cancer in Upper Gastrointestinal Canal, or Second Line Palliative Chemotherapy in Patients With Colorectal Cancer - an Open, Randomised Investigator Initiated Trial.CompletedNCT022467251 country
- Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsCompletedNCT03037385Phase 1/213 countries
- Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CATerminatedNCT01550510Phase 1/21 country
- Exploratory Study of Rectal Mucus for Diagnosing DiseaseCompletedNCT046595901 country
- LuCID - Investigating the Use of a Novel Digital Rectoscope for Community Examinations During COVID-19CompletedNCT050433631 country
- Data Collection of PillCamTM SB3 Capsule Endoscopy and Device-Assisted Enteroscopy Routine Care Procedures (GPS Study)WithdrawnNCT05450393
- Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical TreatmentCompletedNCT047446881 country
- Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal CancerTerminatedNCT00838578Phase 1/21 country
- ASPIRIN Trial BelgiumActive, not recruitingNCT03464305Phase 31 country
- Application of IPC During Surgery to Prevent Venous Thrombosis in Gastrointestinal Surgery Patients.Active, not recruitingNCT06260150Not applicable1 country
- Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal AdenocarcinomaCompletedNCT03559543Phase 21 country
- A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerCompletedNCT02753127Phase 316 countries
- A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsTerminatedNCT04644315Phase 21 country
- Do Good Non-Technical Skills Correlate With Good Clinical Outcomes in Endoscopy?CompletedNCT05110378