Intervertebral Disc Degeneration: all 472 studies

Page 2 of 5. Open to participants first (100), then studies with results posted, then the rest; newest registration first within each.

• TXA in Spinal FusionCompletedNCT04272606Phase 2Results posted
• Retrospective Review of Integrity Implants FlareHawk® for Lumbar FusionCompletedNCT04057235Results posted
• Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar SurgeryTerminatedNCT04007094Not applicableResults posted
• A Comparison of Stryker's Tritanium Posterior Lumbar Cage and PEEK ImplantTerminatedNCT03817606Not applicableResults posted
• Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc DiseaseCompletedNCT03733626Not applicableResults posted
• Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody CagesCompletedNCT03647501Not applicableResults posted
• A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain ReliefTerminatedNCT03514277Phase 4Results posted
• Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc DiseaseCompletedNCT03484403Not applicableResults posted
• ViBone in Cervical and Lumbar Spine FusionCompletedNCT03425682Results posted
• The European Robotic Spinal Instrumentation (EUROSPIN) StudyCompletedNCT03398915Results posted
• BIO4 Clinical Case Study: Cervical SpineCompletedNCT03077204Phase 4Results posted
• An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LP™ Cervical Disc at Two Contiguous Levels in the Cervical SpineTerminatedNCT03062657Not applicableResults posted
• AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDYTerminatedNCT02704689Not applicableResults posted
• Safety and Efficacy of the CarboClear Pedicle Screw SystemCompletedNCT02626624Not applicableResults posted
• 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)CompletedNCT02617563Results posted
• Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and FusionCompletedNCT02539394Not applicableResults posted
• Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine SurgeryCompletedNCT02535000Phase 4Results posted
• Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back PainCompletedNCT02412735Phase 3Results posted
• Spineology Clinical Outcomes Trial: An IDE InvestigationCompletedNCT02347410Not applicableResults posted
• Prospective Study of Thoracolumbar Spinal Fusion GraftCompletedNCT02297256Not applicableResults posted
• Cellentra Viable Cell Bone Matrix (VCBM) Anterior Cervical Discectomy and Fusion Outcomes Study (VCBM/MaxAn)CompletedNCT02182843Not applicableResults posted
• Retrospective/Prospective Data Collection on the LDR ROIC Interbody Fusion Device With VerteBRIDGE PlatingCompletedNCT02104167Results posted
• Retrospective/Prospective Data Collection on the LDR ROIA Interbody Fusion Device With VerteBRIDGE PlatingCompletedNCT02104141Results posted
• Study of an Expandable Interbody Device for the Lumbar SpineCompletedNCT02075554Not applicableResults posted
• Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc DiseaseTerminatedNCT02070484Not applicableResults posted
• Multicenter Study of the Avenue L Interbody Spinal Fusion System Using VerteBRIDGE Plating and Posterior FixationTerminatedNCT02068768Results posted
• Comparison of Complication Rates Between Lateral Approaches to the Lumbar SpineTerminatedNCT02068729Results posted
• Evaluation of Fusion Rate Using K2M VESUVIUS® Demineralized Fibers With K2M EVEREST® Spinal SystemTerminatedNCT02064855Results posted
• Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion DeviceCompletedNCT01944345Results posted
• Retrospective Multicenter Clinical Evaluation of Complications for Single or Multilevel VEO® Lateral Access and Interbody Fusion System and eXtreme Lateral Interbody Fusion (XLIF®) SubjectsCompletedNCT01878149Results posted
• Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)CompletedNCT01860417Phase 1/2Results posted
• Post-Market Study Evaluating the Safety and Effectiveness of NuNec® Cervical Arthroplasty SystemTerminatedNCT01832818Not applicableResults posted
• Assessment of nanOss Bioactive 3D in the Posterolateral SpineCompletedNCT01829997Not applicableResults posted
• Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™CompletedNCT01615328Phase 4Results posted
• Opioid Treatment for Chronic Low Back Pain and the Impact of Mood SymptomsCompletedNCT01502644Phase 4Results posted
• Maverick Total Disc Replacement in a 'Real World' Patient PopulationCompletedNCT01338493Results posted
• Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA SpacerCompletedNCT01323387Not applicableResults posted
• Drug Use Survey (DUS) of Triple Therapy (Methycobal (MBL)+ Myonal (MYO)+ Non-steroidal Anti-inflammatory Drags (NSAID)) on the Symptom Relief of Lumbar DDD in ChinaCompletedNCT01299077Results posted
• Radiographic Analysis Using PureGen Versus Autologous Bone in Posterolateral Fusion (PLF)TerminatedNCT01294007Not applicableResults posted
• TRIUMPH Lumbar Artificial Disc IDE: A Pilot StudyCompletedNCT01198470Not applicableResults posted
• A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc DegenerationCompletedNCT01182337Phase 1/2Results posted
• A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc DegenerationCompletedNCT01158924Phase 1/2Results posted
• A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc DegenerationCompletedNCT01124006Phase 2Results posted
• Satellite™ PEEK Nucleus Replacement Retrospective AnalysisCompletedNCT01110967Results posted
• Clinical Outcomes of Lumbar Degenerative Disc Disease in Active-Duty U.S. Service PersonnelTerminatedNCT01028300Not applicableResults posted
• Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® SystemTerminatedNCT01011816Phase 3Results posted
• Prospective, Multi-Center Clinical Outcomes Study Evaluating the chronOS Strip Combined With Bone Marrow AspirateCompletedNCT00943384Not applicableResults posted
• Trial Evaluating the Safety and Effectiveness of NUBAC™ Disc ArthroplastyCompletedNCT00931515Not applicableResults posted
• Intradiscal rhGDF-5 Phase I/II Clinical TrialCompletedNCT00813813Phase 1/2Results posted
• OptiMesh® for Lumbar Interbody Fusion Trial (OLIF)CompletedNCT00764491Not applicableResults posted
• Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable ScrewsTerminatedNCT00762723Not applicableResults posted
• Ultrasound as Adjunct Therapy for Increasing Fusion Success After Lumbar SurgeryTerminatedNCT00744861Not applicableResults posted
• Study to Investigate the Performance of Cervical Arthroplasty for the Treatment of Cervical Degenerative Disc DiseaseTerminatedNCT00700739Phase 4Results posted
• Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDDCompletedNCT00667459Phase 3Results posted
• Advent™ Cervical Disc Versus ACDF for Treatment of One Level Degenerative Disc Disease (IDE Study)TerminatedNCT00637312Not applicableResults posted
• Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent LevelsCompletedNCT00637156Not applicableResults posted
• Activ-L™ Artificial Disc Treatment of Degenerative Disc Disease in the Treatment of Degenerative Disc DiseaseCompletedNCT00589797Not applicableResults posted
• INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical TrialCompletedNCT00485173Not applicableResults posted
• Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc DiseaseCompletedNCT00443547Results posted
• Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)CompletedNCT00432159Not applicableResults posted
• LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDECompletedNCT00389597Not applicableResults posted
• Safety and Efficacy Study of Healos as a Bone Replacement to Treat Degenerative Disc DiseaseCompletedNCT00316121Phase 3Results posted
• An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With InstrumentationCompletedNCT00310440Not applicableResults posted
• Safety and Efficacy Study Comparing ProDisc-C to ACDF Surgery to Treat SCDDCompletedNCT00291018Not applicableResults posted
• Application of Internet Plus Nursing Intervention in Postoperative Rehabilitation of Patients With Lumbar Disc HerniationCompletedNCT07547410Not applicable
• ISOVUE Comparative TrialCompletedNCT07363759Not applicable
• Comparison of Posterior Cellular Bonegraft Options for Single Level Lumbar Spinal FusionCompletedNCT07187362Phase 2/3
• Investigation of miRNA Expression Profiles in Human Degenerated Intervertebral Disc TissuesActive, not recruitingNCT07114497Not applicable
• Proprio Spine Measurement ToolWithdrawnNCT07023393Not applicable
• Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc ReplacementCompletedNCT06989632
• Facet Tropism in Low Back Pain PatientsCompletedNCT06982118
• Effect Of Paraspinal Muscle Thickness On The Benefit Of Core StabilizationCompletedNCT06969508Not applicable
• ASCEND: A Clinical Trial to Evaluate the Safety and Effectiveness of VIA Disc NP, a Supplement for Degenerated Intervertebral DiscsActive, not recruitingNCT06615505Phase 2
• SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc DegenerationSuspendedNCT06589271Phase 1
• Effect of RECK in Posterior Spinal FusionWithdrawnNCT06447194Phase 1/2
• Multi-Centre Post-Market Data CollectionWithdrawnNCT06413225
• Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back PainActive, not recruitingNCT06325566Phase 3
• Erector Spinae Plane Block vs Local Infiltration Following Fusion SurgeryCompletedNCT06199999Phase 2
• Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc DiseaseActive, not recruitingNCT06155409
• A Phase 3 Study of AGA111 in Patients With Degenerative Disc Disease Undergoing Lumbar Interbody FusionTerminatedNCT06115512Phase 3
• Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back PainActive, not recruitingNCT06053242Phase 1/2
• Natural Matrix Protein™ (NMP™) in Interbody Lumbar FusionCompletedNCT05972616
• Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion DeviceWithdrawnNCT05944081
• Investigation of DEXA-C Anterior Cervical Interbody SystemActive, not recruitingNCT05883436Not applicable
• Cortical Bone Trajectory With Patient GuideCompletedNCT05844358
• The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion SurgeryActive, not recruitingNCT05740176Not applicable
• Lumbar Spine on MRI and Low Back Pain in Elite Cross-country SkiersCompletedNCT05641857
• Comparative Analysis of Virtuos and Autograft in Lumbar FusionTerminatedNCT05614284Not applicable
• Retrospective Study With Patients Treated With STALIF® C or M and Ti or FLX Implants for 1 and 2 LevelsStatus unknownNCT05610397
• Interleukin-1β (rs 1143627 T/C) Gene Polymorphism May Increase the Risk of Developing LDD in Turkish PopulationCompletedNCT05601739
• A Phase I/II Study of AGA111 for Lumbar Interbody Fusion in Patients With Degenerative Disc DiseaseCompletedNCT05574543Phase 1/2
• Retrospective Modulus ALIF StudyCompletedNCT05566704
• 3rd-year Post-surgical Evaluation of Adjacent Segment Disc Degeneration Onset in Lumbar Spine (Spinal Fusion vs. Lumbar Arthroplasty With Disc Replacement)WithdrawnNCT05561322
• Retro Comparison of Subsidence Following Interbody Devices in Lumbar SpineCompletedNCT05536453
• Dynamic Cervical Implant (DCI) Versus Anterior Cervical Discectomy And Fusion(ACDF) For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD): An RCTStatus unknownNCT05522010Not applicable
• Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar SpineActive, not recruitingNCT05516992Phase 3
• PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.TerminatedNCT05489822
• Calculating the Volume of the Paravertebral SpaceCompletedNCT05414604
• VIA Disc Nucleus Pulposus Older Patients PilotActive, not recruitingNCT05412277Not applicable
• Clinical Decision-Making and Virtual Reality ExerciseCompletedNCT05375201Not applicable

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