Immunologic Deficiency Syndromes: all 702 studies

Page 2 of 8. Open to participants first (67), then studies with results posted, then the rest; newest registration first within each.

• Effect of Rifabutin on the Pharmacokinetics of Oral Cabotegravir in Healthy SubjectsCompletedNCT03149848Phase 1Results posted
• Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD SubjectsCompletedNCT03116347Phase 4Results posted
• Safety and Efficacy Study of GSK2838232 in Human Immunodeficiency Virus (HIV)-1 Infected AdultsCompletedNCT03045861Phase 2Results posted
• Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra) in Subjects With Primary Immunodeficiency (PID)CompletedNCT03033745Phase 4Results posted
• A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV RiskCompletedNCT02929069Not applicableResults posted
• Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected AdultsCompletedNCT02919306Phase 1/2Results posted
• Maraviroc Efficacy for Hepatitis CCompletedNCT02881762Phase 4Results posted
• Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLITerminatedNCT02859727Phase 2/3Results posted
• An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)CompletedNCT02831673Phase 3Results posted
• Study to Investigate Efficacy, Safety and Pharmacokinetics of BT595 in Subjects With PIDCompletedNCT02810444Phase 3Results posted
• Efficacy, Pharmacokinetics, Safety, and Tolerability of IGSC 20% in Subjects With Primary ImmunodeficiencyCompletedNCT02806986Phase 3Results posted
• Study of Immune Globulin Intravenous (Human) GC5107 in Subjects With Primary Humoral ImmunodeficiencyCompletedNCT02783482Phase 3Results posted
• Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive AdultsCompletedNCT02741128Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Experimental Drugs ABT- 493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1-6 Infection and Human Immunodeficiency Virus -1 Coinfection (EXPEDITION-2)CompletedNCT02738138Phase 3Results posted
• Impact of Metabolic Syndrome on Flu Vaccine EfficacyTerminatedNCT02653495Not applicableResults posted
• Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary ImmunodeficiencyCompletedNCT02604810Phase 3Results posted
• Dutch Acute HCV in HIV Study (DAHHS-2): Grazoprevir/Elbasvir for Acute HCVCompletedNCT02600325Phase 3Results posted
• Steering Together in a New Direction: Reducing the Risk of HIV/STD Among African American MenCompletedNCT02572401Not applicableResults posted
• Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood CellsTerminatedNCT02512679Phase 2Results posted
• Study of Efficacy of CDZ173 in Patients With APDS/PASLICompletedNCT02435173Phase 2/3Results posted
• A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected SubjectsCompletedNCT02431247Phase 3Results posted
• Comparison of Doravirine, Tenofovir, Lamivudine (MK-1439A) and ATRIPLA™ in Treatment-Naive Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Participants (MK-1439A-021)CompletedNCT02403674Phase 3Results posted
• TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PIDCompletedNCT02327351Phase 2/3Results posted
• Non-Interventional Study on the Tolerability and Efficacy of IVIGCompletedNCT02303093Results posted
• Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2)CompletedNCT02282293Phase 3Results posted
• Expanded Access Protocol Thymus TransplantationCompletedNCT02274662Phase 4Results posted
• Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Regimen Versus Boosted Protease Inhibitor (bPI) Along With Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Regimen in Virologically-Suppressed, HIV-1 Infected ParticipantsCompletedNCT02269917Phase 3Results posted
• Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10%CompletedNCT02269163Phase 3Results posted
• Plerixafor Versus G-CSF in the Treatment of People With WHIM SyndromeCompletedNCT02231879Phase 2/3Results posted
• Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant DiseasesTerminatedNCT02231710Phase 1Results posted
• Tesamorelin Effects on Liver Fat and Histology in HIVCompletedNCT02196831Not applicableResults posted
• Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infectionCompletedNCT02178592Phase 3Results posted
• Effect of Cenicriviroc on HIV Neurocognitive ImpairmentCompletedNCT02128828Phase 2Results posted
• A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult SubjectsCompletedNCT02120352Phase 2Results posted
• An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected PatientsCompletedNCT02103439Phase 3Results posted
• Study to Evaluate the Safety Tolerability and Acceptability of Long Acting Injections of the Human Immunodeficiency Virus (HIV) Integrase Inhibitor, GSK1265744, in HIV Uninfected Men (ECLAIR)CompletedNCT02076178Phase 2Results posted
• Study of Dapivirine Vaginal Ring (VR) in AdolescentsCompletedNCT02028338Phase 2Results posted
• Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)CompletedNCT01998633Phase 2Results posted
• Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive AdultsCompletedNCT01968551Phase 3Results posted
• Efficacy of Tenofovir Alafenamide Versus Placebo Added to a Failing Regimen Followed by Treatment With Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Atazanavir in HIV-1 Positive, Antiretroviral Treatment-Experienced AdultsCompletedNCT01967940Phase 3Results posted
• Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency DiseasesCompletedNCT01963143Phase 3Results posted
• A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 CoinfectionCompletedNCT01939197Phase 2/3Results posted
• Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric ParticipantsTerminatedNCT01923311Phase 2/3Results posted
• A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)CompletedNCT01910402Phase 3Results posted
• Study of Octanorm Subcutaneous IG in Patients With PIDCompletedNCT01888484Phase 3Results posted
• Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency DiseasesCompletedNCT01884311Phase 3Results posted
• CD34+ Stem Cell Infusion to Augment Graft FunctionTerminatedNCT01856582Phase 2Results posted
• Living Well Project for Persons With AIDSCompletedNCT01848483Not applicableResults posted
• Brief Intervention for Rural Women at High Risk for HIV/HCVCompletedNCT01840722Not applicableResults posted
• Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)CompletedNCT01814800Phase 3Results posted
• A Phase 3, Open-label Study to Investigate the Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2, 3 and 4 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected AdultsCompletedNCT01783678Phase 3Results posted
• Atorvastatin for HAART Suboptimal RespondersCompletedNCT01766076Phase 3Results posted
• Effects of Orally Administered Beta-glucan on Leukocyte Function in HumansCompletedNCT01727895Not applicableResults posted
• Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in AdolescentsCompletedNCT01721109Phase 2/3Results posted
• A Clinical Trial Comparing the Efficacy of Tenofovir Disoproxil Fumarate/Emtricitabine/Rilpivirine (TDF/FTC/RPV) Versus TDF/FTC/Efavirenz (TDF/FTC/EFV) in Patients With Undetectable Plasma HIV-1 RNA on Current First-line TreatmentCompletedNCT01709084Phase 3Results posted
• Safety and Efficacy of E/C/F/TDF Versus RTV-Boosted ATV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment-Naive WomenCompletedNCT01705574Phase 3Results posted
• Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2 and 3 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected AdultsCompletedNCT01667731Phase 3Results posted
• Real-life Effectiveness of the Kaletra Adherence Support Assistance (KASA) ProgramCompletedNCT01662336Results posted
• Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus RilpivirineCompletedNCT01641809Phase 2Results posted
• Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical CancerCompletedNCT01590017Phase 2Results posted
• Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)CompletedNCT01581593Phase 3Results posted
• D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive AdultsCompletedNCT01565850Phase 2Results posted
• HIV, Buprenorphine, and the Criminal Justice SystemCompletedNCT01550341Not applicableResults posted
• Open-Label Pilot Study to Evaluate Switching From a Regimen Consisting of Raltegravir Plus Emtricitabine/Tenofovir DF Fixed-Dose Combination to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected PatientsCompletedNCT01533259Phase 3Results posted
• Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r)CompletedNCT01516970Phase 3Results posted
• Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive AdultsCompletedNCT01497899Phase 2Results posted
• Study to Evaluate Switching From Regimens Consisting of a Nonnucleoside Reverse Transcriptase Inhibitor Plus Emtricitabine and Tenofovir DF to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected PatientsCompletedNCT01495702Phase 3Results posted
• Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African MenCompletedNCT01490359Not applicableResults posted
• Tolerability and Safety of IGI, 10% With rHuPH20 in PIDDCompletedNCT01485796Phase 2/3Results posted
• A Study to Assess the Safety, Tolerability and Efficacy of TMC435 Along With Pegylated Interferon Alpha-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hepatitis C Genotype-1 Infected Patients Co-infected With Human Immunodeficiency Virus-Type 1CompletedNCT01479868Phase 3Results posted
• Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor Plus Emtricitabine/Tenofovir Fixed-Dose Combination to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected PatientsCompletedNCT01475838Phase 3Results posted
• Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary ImmunodeficiencyCompletedNCT01465958Phase 4Results posted
• Follow-up Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)CompletedNCT01458171Phase 3Results posted
• A Study of the Neurological Effects of Adding Maraviroc to HAART Regimen in Patients With HIV (HANDmac)CompletedNCT01449006Phase 4Results posted
• A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current TreatmentCompletedNCT01448707Phase 3Results posted
• A Study of the Neurological Effects of Adding Raltegravir to HAART Regimen in Patients With HIVTerminatedNCT01448486Phase 4Results posted
• Safety and Efficacy of Cobicistat-boosted Darunavir in HIV Infected AdultsCompletedNCT01440569Phase 3Results posted
• EZN-2279 in Patients With ADA-SCIDCompletedNCT01420627Phase 3Results posted
• A Study to Compare Brachial Artery Reactivity and Cardiovascular Risk of a Treatment Simplification by Darunavir/Ritonavir (DRV/r) 800/100 mg Versus a Triple Combination Therapy Containing DRV/r in HIV-1 Infected PatientsCompletedNCT01391013Phase 2Results posted
• HIV Attachment Inhibitor to Treat Human Immunodeficiency Virus 1 (HIV-1) InfectionsCompletedNCT01384734Phase 2Results posted
• Cobicistat-containing Highly Active Antiretroviral Regimens in HIV-1 Infected Patients With Mild to Moderate Renal ImpairmentCompletedNCT01363011Phase 3Results posted
• Drug Use Investigation of Kaletra Tablets (Once Daily Administration) on Patients With HIV-infectionCompletedNCT01328158Results posted
• High Infusion Rate Study of Immunoglobulin Intravenous (Human) 10% (NewGam)CompletedNCT01313507Phase 3Results posted
• A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary ImmunodeficiencyCompletedNCT01289847Phase 4Results posted
• Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET)TerminatedNCT01231555Phase 2Results posted
• Phase 2/3 Study of IGSC, 20% in PIDDCompletedNCT01218438Phase 2/3Results posted
• A Study to Assess the Efficacy of Raltegravir (Isentress®), Administered in Combination With Other Antiretroviral Drugs as Treatment for Adults and Older Adults Infected With the Human Immunodeficiency Virus 1 (HIV-1)(MK-0518-145) (Wirksamkeit Von Isentress® Unter Praxisbedingungen)CompletedNCT01213316Results posted
• A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced PatientsCompletedNCT01199939Phase 2Results posted
• Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)CompletedNCT01199705Phase 3Results posted
• Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & FilgrastimTerminatedNCT01182675Phase 2Results posted
• Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PIDCompletedNCT01175213Phase 3Results posted
• Long-term Effectiveness and Safety in Hepatitis-co-infected PatientsCompletedNCT01153269Results posted
• Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous DiseaseTerminatedNCT01147042Phase 4Results posted
• Study on the Usage, Dosing, Tolerability, and Effectiveness of Kaletra TabletCompletedNCT01097655Results posted
• Study of Vitamin D and Effect on Heart Disease and Insulin ResistanceCompletedNCT01093417Phase 2Results posted
• Mesalamine to Reduce T Cell Activation in HIV InfectionCompletedNCT01090102Phase 4Results posted
• Evaluation of Kaletra Therapy Over the Long-termCompletedNCT01083810Results posted
• Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution SyndromeCompletedNCT01077960Phase 3Results posted
• Alcohol Pharmacotherapy for HIV+ PrisonersCompletedNCT01077310Not applicableResults posted
• Special Investigation of Kaletra in Pregnant WomenCompletedNCT01076985Results posted

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