Immunologic Deficiency Syndromes: all 702 studies
Page 1 of 8. Open to participants first (67), then studies with results posted, then the rest; newest registration first within each.
- Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIMEnrolling by invitationNCT07775313Phase 1/2
- Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating MutationsNot yet recruitingNCT07670156Phase 1/2
- Toxin Exposure and Immune Dysregulation in Non-Hodgkin LymphomaRecruitingNCT07652580
- Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without ThymectomyRecruitingNCT07416201
- OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 PatientsRecruitingNCT07406217Phase 2
- Study of a Cohort of Non-HIV Immunocompromised Patients With Toxoplasmosis at the Strasbourg University HospitalRecruitingNCT07299500
- Assessing Patient Preference for Infusion SystemsNot yet recruitingNCT07189013Not applicable
- Impact of Thymectomy on Immunity in Infants After Cardiac SurgeryRecruitingNCT07019857Not applicable
- Efficacy, Safety and Pharmacokinetic of Virchow IVIG in PID PatientsNot yet recruitingNCT07017036Phase 3
- Shwachman-Diamond Syndrome Global Patient Survey and Partnering PlatformRecruitingNCT06999954
- V-IMMUNE: A Novel Immunoglobulin Therapy for ImmunodeficiencyRecruitingNCT06954441Phase 3
- R-MVST Cells for Treatment of Viral Infections in Children and Young AdultsRecruitingNCT06926894Phase 1
- Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCTRecruitingNCT06839456Phase 1/2
- Developing a Patient-Reported Outcome (PRO) Screening Measure for Infections and Measuring Quality of Life in Hematological Patients With Secondary Immunodeficiency (SID) Across the Treatment Trajectory - The PRO SID ProjectRecruitingNCT06821880
- Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell Sequential Allo-HSCT and Kidney Transplantation in the Treatment of SIODRecruitingNCT06769191Early Phase 1
- Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular TherapyRecruitingNCT06689800Not applicable
- Inbon Errors of Immunity Attending Assiut University Children&Amp;#39;s Hospital: a Single Center StudyNot yet recruitingNCT06649643
- Clozapine-related Immunodeficiency in Parkinsons DiseaseRecruitingNCT06634641Phase 4
- Vaccine-induced Immunity in Immunocompromised PatientsRecruitingNCT06612515
- Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency VirusNot yet recruitingNCT06603727Not applicable
- Description of the Immune Deficiency in Patients With Untreated Chronic Lymphocytic Leukemia and Search for Predictive Factors of Infectious RiskRecruitingNCT06475469Not applicable
- Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic ESKD Patients.RecruitingNCT06474169
- Immunodeficiency and Cancer: Identification of Congenital Immune System Defects Underlying Paediatric LymphomasRecruitingNCT06332196Not applicable
- A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of HIV/AIDS Complicated With InfectionNot yet recruitingNCT06280001
- X-linked Moesin Associated ImmunodeficiencyRecruitingNCT06278337
- Human Immunodeficiency Virus Pre-exposure Prophylaxis Program in General PracticeNot yet recruitingNCT06258876
- Efficacy, Safety, and Pharmacokinetics of Shu Yang IVIGNot yet recruitingNCT06089122Phase 3
- Exercise Capacity, Physical Activity Level and Quality of Life in Children With Primary ImmunodeficiencyRecruitingNCT05999422
- Evaluating Bronchodilator Response in Patients With BronchiectasisRecruitingNCT05932316Not applicable
- V+PSF-M for Tobacco Cessation in HIV Care in IndiaRecruitingNCT05786547Phase 3
- The Experience of Screening for SCIDRecruitingNCT05651113
- OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy TrialRecruitingNCT05587894Phase 2
- Allergy and Immunology Natural History StudyRecruitingNCT05584488
- An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of Antiretroviral TherapyEnrolling by invitationNCT05540964
- Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF ToxicityNot yet recruitingNCT05493969Phase 4
- Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older AdultsRecruitingNCT05421325Phase 2
- Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical VentilationRecruitingNCT05405491Not applicable
- Study of Entry and Continuation in Care for People Living With HIV in French GuianaRecruitingNCT05354934
- Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisRecruitingNCT05333471Phase 1/2
- Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIVRecruitingNCT05266898Phase 4
- A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) SyndromeRecruitingNCT05027945Phase 2
- Systematic Screening for Primary Immunodeficiencies in Patients Admitted for Severe Infection in Pediatric Intensive Care UnitRecruitingNCT04990908
- Biologics And Clinical Immunology Cohort at SinaiRecruitingNCT04784364
- Immune Homeostasis in Sepsis and Septic ShockRecruitingNCT04448951
- Gene Therapy for X Linked Severe Combined ImmunodeficiencyRecruitingNCT04286815Not applicable
- Fostemsavir Compassionate Use Named Patient Program for the Treatment of Human Immunodeficiency Virus 1 (HIV-1)AvailableNCT04233047
- Sequential Transplantation of UCBSCs and Islet Cells in Children and Adolescents With Monogenic Immunodeficiency T1DMRecruitingNCT03835312Not applicable
- Lentiviral Gene Therapy for X-linked Severe Combined ImmunodeficiencyRecruitingNCT03601286Phase 1
- Strimvelis Registry Study to Follow-up Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID)Enrolling by invitationNCT03478670
- Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseRecruitingNCT03300830
- Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSCAvailableNCT03145545
- Umbilical Cord Blood Transplantation From Unrelated DonorsRecruitingNCT03016806
- Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary ImmunodeficienciesRecruitingNCT02735824
- Natural History of Noncirrhotic Portal HypertensionRecruitingNCT02417740
- Expanded Access Protocol Using CD3+/CD19+ Depleted PBSCRecruitingNCT02356653Early Phase 1
- Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisRecruitingNCT02190266
- Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood TransplantsAvailableNCT01881334
- Allogeneic Hematopoietic Stem Cell Transplant for GATA2 MutationsRecruitingNCT01861106Phase 2
- Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)RecruitingNCT01666080Not applicable
- Apheresis of Patients With ImmunodeficiencyRecruitingNCT01212055
- Natural History Study of SCID DisordersEnrolling by invitationNCT01186913
- The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known ImmunocompromiseRecruitingNCT01011712
- Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaRecruitingNCT00867269
- Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)RecruitingNCT00006150
- Genetic Analysis of Immune DisordersRecruitingNCT00001467
- Detection and Characterization of Host Defense DefectsRecruitingNCT00001355
- Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIVRecruitingNCT00001281
- Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 DeficiencyActive, not recruitingNCT05907746Phase 2Results posted
- Study to Assess the Effects of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injections Following Sub-cutaneous (SC) Administration Compared With Intramuscular (IM) Administration in Adult Participants Living With Human Immunodeficiency Virus (HIV-1) Infection in the FLAIR StudyCompletedNCT05896748Phase 3Results posted
- ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised IndividualsTerminatedNCT05655546Not applicableResults posted
- A Study of MGD020 Alone or Combined With MGD014 in Persons With HIV-1 on Antiretroviral TherapyCompletedNCT05261191Phase 1Results posted
- A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult ParticipantsActive, not recruitingNCT05217641Phase 1Results posted
- A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID)CompletedNCT05150340Phase 3Results posted
- COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and DysregulationsCompletedNCT04852276Results posted
- An Extension Study of TAK-664 for Japanese People With Primary Immunodeficiency DiseaseCompletedNCT04842643Phase 3Results posted
- Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in MenCompletedNCT04772469Not applicableResults posted
- A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary ImmunodeficiencyCompletedNCT04566692Phase 4Results posted
- A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral ImmunodeficiencyCompletedNCT04561115Phase 3Results posted
- A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID)CompletedNCT04346108Phase 3Results posted
- Quality Assurance of Secondary Immunodeficiencies (SID) in CLL/MM PatientsCompletedNCT04172467Results posted
- Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH)CompletedNCT04135937Phase 4Results posted
- Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency DiseasesCompletedNCT03988426Phase 3Results posted
- Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency DiseasesCompletedNCT03939533Phase 3Results posted
- CLINICAL PHASE III STUDY TO MONITOR THE SAFETY, TOLERABILITY AND EFFICACY OF SUBCUTANEOUS HUMAN IMMUNOGLOBULIN (OCTANORM) IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES, INCLUDING (BUT NOT LIMITED TO) THOSE WHO HAVE COMPLETED THE SCGAM-01 TRIALCompletedNCT03907241Phase 3Results posted
- Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy AdultsCompletedNCT03783130Phase 1Results posted
- Technological Intervention for Reducing Alcohol Use Among People Living With HIV/AIDSCompletedNCT03746600Not applicableResults posted
- Primary Immunodeficiency in KuwaitCompletedNCT03618147Results posted
- A Study of MK-8527 in Human Immunodeficiency Type 1 Virus (HIV-1) Infected Participants (MK-8527-002)CompletedNCT03615183Phase 1Results posted
- Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIVCompletedNCT03575143Results posted
- Effectiveness & Implementation of a Behavioral Intervention for Adherence and Substance Use in HIV Care in South AfricaCompletedNCT03529409Not applicableResults posted
- Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
- Clinical Trial of HIV Vaccine Combinations in Healthy Men and WomenCompletedNCT03408262Phase 1Results posted
- Computer-based Intervention for Alcohol-using HIV/HCV+ WomenCompletedNCT03362476Not applicableResults posted
- Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
- Positive Attitudes Concerning Infant Feeding- a Questionnaire for Women Living With HIVCompletedNCT03294499Results posted
- Positive Health Check Evaluation TrialCompletedNCT03292913Not applicableResults posted
- Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric PIDD SubjectsCompletedNCT03277313Phase 3Results posted
- Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-InfectionCompletedNCT03235349Phase 3Results posted
- A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-InfectionCompletedNCT03222583Phase 3Results posted
- Video Information Provider for HIV-Associated Non-AIDS (VIP-HANA) SymptomsCompletedNCT03182738Not applicableResults posted