Hoarseness clinical trials
The registry lists 52 studies for Hoarseness across more than 10 countries. 9 are recruiting or about to start. 25 of them are mainly about Hoarseness (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Who runs them
Seoul National University Hospital (6) · University of Rostock (3) · B.P. Koirala Institute of Health Sciences (2) · Universiti Sains Malaysia (2) · EndoGastric Solutions (1) · Seth Gordhandas Sunderdas Medical College (1) · Saint Petersburg State University, Russia (1) · University of Utah (1)
What is being tested here
Drugs under test in Hoarseness studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexamethasone | 3 | 0 | 6 |
| Hydrocortisone acetate | 1 | 0 | 1 |
| Hydrocortisone | 1 | 0 | 1 |
| Lidocaine | 0 | 2 | 3 |
| Sevoflurane | 0 | 0 | 2 |
| Flurbiprofen | 0 | 0 | 1 |
| Ketorolac | 0 | 0 | 1 |
| Betamethasone | 0 | 1 | 1 |
| Water | 0 | 1 | 1 |
| Rocuronium | 0 | 0 | 1 |
Drug classes tested here Corticosteroids 4 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Dec 2026Sore Throat After Open Neck Elective Surgery · Saint Petersburg State University, Russia
- Dec 2026Dexmedetomidine Nasal Spray and Postoperative Sore Throat After Bronchoscopy · Shanghai Pulmonary Hospital, Shanghai, China
- Dec 2026Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia · Zhejiang University
- Dec 2026Efficacy of Flurbiprofen Spray for Postoperative Sore Throat Following Double-Lumen Endobronchial Intubation · Kittitorn Supphapipat, MD
- Jan 2027Effects of Video LMA Cuff Pressure in Tympanoplasty. · Samsun University
- Jan 2027Intraperitoneal Dexamethasone Spraying on Vagal Nerve-Rich Areas for Prevention of Hoarseness After Upper Abdominal Surgery · Fujian Medical University Union Hospital
- Mar 2027Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder Arthroscopy · Fatih Sultan Mehmet Training and Research Hospital
- Jun 2027Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy · B.P. Koirala Institute of Health Sciences
Who these studies take
Of the 5 Hoarseness studies recruiting now, 3 (60%) set no upper age limit and 2 (40%) stop at 75 or younger. 2 (40%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (40%) | 2 (40%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 4 (80%) | 4 (80%) |
| 40 | 4 (80%) | 4 (80%) |
| 50 | 4 (80%) | 4 (80%) |
| 65 | 4 (80%) | 4 (80%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 52 studies, recruiting or not: 46% stop at 75 or younger and 25% at 65; 12% take children; 8% are for women only and 0% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hoarseness studies take
Of 21 interventional studies with no phase under Hoarseness, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo9–24 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Dexmedetomidine Nasal Spray and Postoperative Sore Throat After BronchoscopyOct 26, 2026NCT07894224
Studies
Recruiting first, then most recently updated. Showing 50 of 52. Browse all 52 → or search them.
- Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder ArthroscopyNot yet recruitingNCT078527021 country
- Effects of Video LMA Cuff Pressure in Tympanoplasty.Not yet recruitingNCT078493221 country
- Intraperitoneal Dexamethasone Spraying on Vagal Nerve-Rich Areas for Prevention of Hoarseness After Upper Abdominal SurgeryRecruitingNCT07722091Not applicable1 country
- Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic CholecystectomyNot yet recruitingNCT07760272Not applicable
- Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic AppendectomyRecruitingNCT07678086Not applicable1 country
- Sore Throat After Open Neck Elective SurgeryRecruitingNCT07124650Phase 41 country
- A Randomized, Comparative, Controlled Study of Differences in the Incidence of Postoperative Sore Throat (POST) by Inner Diameter Size of the TaperGuardTM Endotracheal Tube (ETT)Enrolling by invitationNCT07511998Not applicable1 country
- Laryngopharyngeal Injury After Endotracheal Intubation Under General AnesthesiaRecruitingNCT073595861 country
- The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and HypocalcaemiaRecruitingNCT05732883Phase 21 country
- Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast SurgeryCompletedNCT07341646Not applicable1 country
- Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore ThroatCompletedNCT07842081Not applicable1 country
- Dexmedetomidine Nasal Spray and Postoperative Sore Throat After BronchoscopyActive, not recruitingNCT078942241 country
- Hyaluronic Acid for Prevention of Post-Intubation Sore Throat and HoarsenessCompletedNCT07040631Not applicable1 country
- Straw Phonation Exercise Program for Pitch ExtensionActive, not recruitingNCT05357222Not applicable1 country
- Efficacy of Flurbiprofen Spray for Postoperative Sore Throat Following Double-Lumen Endobronchial IntubationActive, not recruitingNCT07163429Not applicable1 country
- A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold ScarringCompletedNCT04290182Phase 1/21 country
- Effect of Cuff Pressure of Endotracheal Tube on POSTCompletedNCT055428231 country
- Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff PressureActive, not recruitingNCT07315490Phase 2/31 country
- Thermosoftening of Double-lumen Tube for Airway Exchanger CatheterCompletedNCT03846713Not applicable1 country
- The Effect of Ice, Green Tea and Arnica Montana Application on Post-Operative Intubation Related Sore Throat and HoarsenessCompletedNCT05048628Not applicable1 country
- Intubation with Different Angled Intubation Tubes Using C-macr D Blade Videolaringoscope;CompletedNCT06011967Not applicable1 country
- Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold NodulesCompletedNCT05878197Not applicable1 country
- Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump SprayCompletedNCT06213116Not applicable1 country
- Intensive Versus Traditional Voice TherapyCompletedNCT03129880Not applicable1 country
- Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal MaskCompletedNCT04915534Not applicable1 country
- Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal InjuryActive, not recruitingNCT06108271Not applicable1 country
- The Effectiveness of Preemptive Nebulized Dexamethasone in Reducing Post-Operative Sore Throat in Supraglottic AirwayCompletedNCT04771026Not applicable1 country
- Incidence of Hoarseness After General Spine Surgery: Prospective Observational StudyCompletedNCT059961461 country
- A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for IntubationCompletedNCT05531617Not applicable1 country
- The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative PeriodStatus unknownNCT05317156Not applicable
- The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients.Status unknownNCT04412694Phase 41 country
- Does Tracheal Tube Size Affect Patient's Experience of Postoperative Sore Throat and HoarsenessCompletedNCT04184778Not applicable1 country
- Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF StudyTerminatedNCT01327963Not applicable1 country
- Endobronchial Intubation of Double-lumen Tube: Conventional Method vs Fiberoptic Bronchoscope Guide MethodCompletedNCT03368599Not applicable1 country
- The Effect of Reinforced Endotracheal Tube on Post-operative Hoarseness Undergoing ThyroidectomyCompletedNCT03368911Not applicable1 country
- Screening for Barrett's Esophagus in Otolaryngology PatientsCompletedNCT00695227Not applicable1 country
- The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid SurgeryCompletedNCT02039427Not applicable1 country
- Randomized Controlled Trial of Voice on Children With Vocal NodulesCompletedNCT012557352 countries
- Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.CompletedNCT01990781Phase 41 country
- Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous LesionsCompletedNCT02217358Not applicable1 country
- Comprehensive Voice Rehabilitation Program Compared With Vocal Function ExercisesCompletedNCT02409758Early Phase 1
- Rigid Video Stylet Vs Conventional Lightwand IntubationStatus unknownNCT02073786Not applicable1 country
- Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant)CompletedNCT01896245Not applicable1 country
- The Cuff Pressure of an Endotracheal Tube After Supine-to-lateral Position ChangeStatus unknownNCT02165319Not applicable1 country
- Benefits of Exchanging a Double Lumen Tube to a Proseal Laryngeal Mask or a Single Lumen Tube After a Thoracic SurgeryCompletedNCT00925613Phase 31 country
- Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness ofCompletedNCT02114021Phase 31 country
- Post-operative Sore Throat as Determined by Endotracheal Tube Inflation TechniqueCompletedNCT01305265Not applicable1 country
- Predictive Value of Subjective and Objective Measurement Tools for Extraesophageal RefluxStatus unknownNCT01829074
- Laryngeal Injuries After Anesthesia Induction With Sevoflurane and After Anesthesia Induction With RocuroniumCompletedNCT01591031Not applicable1 country
- Thermosoftening of Double-lumen Tube to Reduce Sore ThroatCompletedNCT01626365Not applicable1 country