Hepatitis B, Chronic: all 954 studies

Page 5 of 10. Open to participants first (147), then studies with results posted, then the rest; newest registration first within each.

• Phase 1 Study of 162, a Novel Neutralizing Antibody Targeting Hepatitis B Surface Antigen, in Healthy Adult SubjectsCompletedNCT05310487Phase 1
• Ethnobridging Study in Healthy Volunteers, Chinese and Japanese SubjectsTerminatedNCT05298332Phase 1
• Performance of Novel Simplified Score for Chronic Hepatitis B Treatment Eligibility in ThailandStatus unknownNCT05295914
• Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis BCompletedNCT05286346Phase 4
• The Effect of Education on Drug Compliance and Quality of Life in Hepatitis B PatientsStatus unknownNCT05286216Not applicable
• A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis BCompletedNCT05282407Phase 4
• A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) TherapyCompletedNCT05276297Phase 2
• A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy VolunteersCompletedNCT05273775Phase 1
• Aerobic Exercise Training in Patients With Chronic Hepatitis B and Hepatic SteatosisCompletedNCT05265026Not applicable
• Disease Loads and Status of TreatmentStatus unknownNCT05264272
• Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis BStatus unknownNCT05256823Phase 2
• A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B PatientsCompletedNCT05244057Phase 2
• A Study of Cetrelimab in Participants With Chronic Hepatitis B Virus InfectionCompletedNCT05242445Phase 1
• A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus InfectionTerminatedNCT05238844Phase 2
• Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low ViremiaStatus unknownNCT05203055Phase 1/2
• Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388(2) in Healthy SubjectsCompletedNCT05189288Phase 1
• Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)Status unknownNCT05177926Phase 4
• Effect of Entecavir Versus Tenofovir on HBV DNA Level in Peripheral Blood Mononuclear CellsStatus unknownNCT05168293
• Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B PatientsActive, not recruitingNCT05147090Phase 4
• A Study of LP-128 Capsules in Healthy SubjectsActive, not recruitingNCT05130567Phase 1
• Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its ComplicationStatus unknownNCT05128305Phase 3
• A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus InfectionCompletedNCT05123599Phase 1
• Study to Evaluate Safety and Efficacy of ASC42 Combined With ETV and PEG-IFN α-2a in Subjects With HBVCompletedNCT05107778Phase 2
• T-cell Dysfunction in Chronic HBV InfectionStatus unknownNCT05099458Not applicable
• A Clinical Research on Disease Progression and Intervention of Chronic HepatitisBStatus unknownNCT05057065
• ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC DiscontinuationStatus unknownNCT05045261Phase 2
• A Single and Repeated Dose Escalation of RBD1016 in Subjects with Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT05017116Phase 1
• A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB SubjectsTerminatedNCT05001022Phase 1
• The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in ChinaStatus unknownNCT04997564Phase 4
• Effort to Narrow the Gap Between in Accordance With Guidelines and Consent to Treat CHB Population in East of ChinaStatus unknownNCT04980664Not applicable
• A 2 PART STUDY EVALUATING EDP-721 IN HEALTHY SUBJECTS AND EDP-721 IN COMBINATION WITH EDP-514 IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION.TerminatedNCT04971512Phase 1
• Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF)Active, not recruitingNCT04939441Phase 4
• The Impact of Tenofovir Alafenamide on Profiles of Body Weight and Metabolic Features in Chronic Hepatitis B Patients.Status unknownNCT04886336
• Molecular Epidemiology of Hepatitis B in Cayenne General Hospital, French GuianaStatus unknownNCT04886102
• Efficacy and Safety of TAF for 48 Weeks in HBeAg Positive CHB PatientsStatus unknownNCT04864366
• Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT04856085Phase 2
• Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis BStatus unknownNCT04850950Phase 4
• A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus CoinfectionTerminatedNCT04847440Phase 2
• A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis BCompletedNCT04846491Phase 3
• Predictive Model for Prognosis of Chronic HBV Infection MothersStatus unknownNCT04805034
• Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis BCompletedNCT04782375Phase 4
• Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA LevelsActive, not recruitingNCT04780204Phase 4
• COIN-B: COntrolled Interruption of Nucleos(t)Ide Analogue Treatment in Chronic Hepatitis B InfectionsActive, not recruitingNCT04779970Not applicable
• Evaluation of Liver Fibrosis With 2D-Shear Wave ElastographyCompletedNCT04759521
• Real World Study About Anti-viral Regimen Adjustment on Achieving Complete Response in CHB PatientsStatus unknownNCT04724785
• Spirulina (FEM-102) Supplement to Chronic Hepatitis B PatientsCompletedNCT04718831Not applicable
• Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388 in Healthy SubjectsStatus unknownNCT04676893Phase 1
• Prevalence of Occult Hepatitis B Virus Infection（OBI） in Subjects With Chronic Hepatitis B（CHB） Family HistoryStatus unknownNCT04672915
• TDF Combined With LDT for the Treatment of HBeAg-positive Hepatitis B Patients With Poor Response to TDF for 12 MonthsStatus unknownNCT04650828
• Study of Entecavir for Reducing the Risk of Hepatocellular Carcinoma in Chronic Hepatitis B PatientsStatus unknownNCT04646928
• LDT Combined With TDF to Improve EGFR Decreasing in Patients With Chronic Hepatitis B Treated With TDFStatus unknownNCT04643990
• The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D InfectionCompletedNCT04638439Phase 1
• A Study to Evaluate the Mass Balance Absorption and AME of VBRCompletedNCT04637139Phase 1
• Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis BCompletedNCT04629976Phase 1
• Clinical Trials to Compare the Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Significant Hepatic Fibrosis With Type 2 DiabetesStatus unknownNCT04584242Phase 4
• Study on Antiviral Therapy for HBeAg-positive Chronic Hepatitis B Patients Aged 1-16 YearsStatus unknownNCT04565262Phase 4
• GLS4/RTV and TAF Drug-drug InteractionCompletedNCT04551261Phase 1
• Pradefovir Treatment for the Patients With Chronic Hepatitis B Virus Infections: a Phase3 StudyStatus unknownNCT04543565Phase 3
• Clinical Trial to Evaluate the Efficacy and Safety of TenofoBell® Tablet in Chronic Hepatitis B PatientsCompletedNCT04539652Phase 4
• A Cross-sectional Study for Renal Function of Patients With Chronic Hepatitis B in ChinaStatus unknownNCT04538651
• Evaluation HEC121120 Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of StudyTerminatedNCT04536532Phase 1/2
• A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB SubjectsCompletedNCT04536337Phase 1
• Biomarkers Guided Stopping NAs TreatmentStatus unknownNCT04519359Not applicable
• Plasma Purification and Chronic Hepatitis BStatus unknownNCT04518553Not applicable
• Efficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B InfectionStatus unknownNCT04507607Early Phase 1
• The Efficacy and Safety of TAF vs Other NAs in Patients With LVLStatus unknownNCT04501224Not applicable
• Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside AnalogueActive, not recruitingNCT04496882Phase 4
• A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB SubjectsTerminatedNCT04485663Phase 1
• A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Oral HRS5091 in Healthy Subjects and Chronic Hepatitis B PatientsStatus unknownNCT04480294Phase 1
• A Study of EDP-514 in Patients With Chronic Hepatitis B Virus Infection Who Are Not Currently on TreatmentCompletedNCT04470388Phase 1
• A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B PatientsCompletedNCT04465890Phase 2
• Safety, Tolerability, Pharmacokinetics(PK), Pharmacodynamics(PD) and Food Effect of HRS9950 in Healthy and CHB SubjectsCompletedNCT04464733Phase 1
• Stopping Antiviral Treatment in Chronic Hepatitis BActive, not recruitingNCT04431245
• A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis BCompletedNCT04426968Phase 2
• A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With EntecavirCompletedNCT04365933Phase 2
• A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and CirrhosisStatus unknownNCT04301908
• Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus InfectionCompletedNCT04294498Phase 2
• A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B VaccineCompletedNCT04289987Phase 2
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers.Status unknownNCT04277897Phase 1
• A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy AdultsCompletedNCT04271592Phase 1
• A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT04248426Phase 1
• Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical TransmissionStatus unknownNCT04237376
• Maternal Therapy With TAF Versus TDF to Prevent Vertical Transmission of Hepatitis BStatus unknownNCT04211805
• Combination of ETV, TQ-A3334 and TQ-B2450 for CHB (Neptune Study)CompletedNCT04202653Phase 2
• Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)IdesStatus unknownNCT04201808Phase 4
• Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis bStatus unknownNCT04195074Not applicable
• Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) Combined With Nucleoside (Acid) Analogues in Chronic Hepatitis B PatientsStatus unknownNCT04189276Phase 2
• Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis BCompletedNCT04182321Not applicable
• A Study of TQ-A3334 Combined With Entecavir in the Treatment of Chronic Hepatitis BStatus unknownNCT04180150Phase 2
• Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) in Chronic Hepatitis B PatientsCompletedNCT04168333Phase 1
• Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated CirrhosisStatus unknownNCT04160897
• An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Tenofovir in Naive Patients With Chronic Hepatitis bStatus unknownNCT04157699Phase 2
• An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Entecavir or Tenofovir in Patients With Chronic Hepatitis b Who Have Received Nucleoside (Acid) TherapyStatus unknownNCT04157257Phase 2
• A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy AdultsCompletedNCT04142762Phase 1
• Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis BStatus unknownNCT04135235
• Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B PatientsStatus unknownNCT04133259Phase 2
• Halting Nucleoside Analogues in Chronic Hepatitis BActive, not recruitingNCT04102176Not applicable
• A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy AdultsCompletedNCT04083716Phase 1
• Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:Status unknownNCT04070079Phase 4
• Maintaining Antiviral Efficacy After Switching to Generic Entecavir 1 mg for Chronic Hepatitis BStatus unknownNCT04069858Phase 4

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