Hepatitis B, Chronic: all 954 studies

Page 4 of 10. Open to participants first (147), then studies with results posted, then the rest; newest registration first within each.

• A Phase II/III of Hepenofovir Fumarate Tablets (HTS) for Chronic Hepatitis BActive, not recruitingNCT07203118Phase 2/3
• A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Treated Patients With Chronic Hepatitis BActive, not recruitingNCT07190742Phase 2
• A Clinical Study of HT-101 and/or HT-102 in Patients With Chronic Hepatitis B Virus InfectionActive, not recruitingNCT07183306Phase 1/2
• Metabolic Associated Fatty Liver Disease and Pancreatic Steatosis in Obese Versus Lean Chronic Hepatitis B PatientsCompletedNCT07175688
• A Phase II Clinical Study of BW-20507 in Combination With PEG-IFNα for the Treatment of Hepatitis BActive, not recruitingNCT07135349Phase 2
• A Study of SN2001 Dose, Safety & Immunogenicity in Healthy AdultsActive, not recruitingNCT07059403Phase 1
• A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)Active, not recruitingNCT06993480Phase 2
• A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected SubjectsWithdrawnNCT06990776Phase 2
• A Study to Evaluate the Safety and Immunogenicity of an Investigational Vaccine for Chronic Hepatitis B Virus Infection, in Healthy AdultsCompletedNCT06989788Phase 1
• A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)Active, not recruitingNCT06963710Phase 2
• Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants With Chronic Hepatitis B (CHB)Active, not recruitingNCT06829329Phase 2
• This is a Phase 1 Study in Which Healthy Volunteers and Participants with Chronic HBV Infection Will Receive HT-101 or Placebo and Will Be Assessed for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral ActivityCompletedNCT06746311Phase 1
• Phase 1 Study of HT-102 Administered Subcustaneously in Healthy Participants and Patients with Chronic Hepatitis B for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral Activity (only in Participants with Chronic HBV Infection)CompletedNCT06744686Phase 1
• Long-term Safety and Efficacy of Tenofovir Amibufenamide in Patients With CHBActive, not recruitingNCT06743438Phase 4
• Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV InfectionActive, not recruitingNCT06706310Phase 2
• Linkage to Care and Treatment of Chronic HBV PatientsCompletedNCT06658678Not applicable
• naVIGation Invitations Liver surveillANce upTakeActive, not recruitingNCT06635694
• Bioequivalence Study of Two Products of Tenofovir Alafenamide 25 mg Film Tablet in Healthy, Adult, Human SubjectsCompletedNCT06592300Phase 1
• Liver Status and Presence of MASLD/MASH in Patients With Chronic Hepatitis BCompletedNCT06573190
• Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB).CompletedNCT06550128Phase 2
• Efficacy and Safety Study of Peginterferon Alfacon-2 to Treat Chronic Hepatitis B Virus InfectionCompletedNCT06544551Phase 3
• A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)Active, not recruitingNCT06537414Phase 2
• Impact of Fatty Liver on Hepatitis B TherapyActive, not recruitingNCT06535048
• Study to Evaluate the Tolerability, Safety, Pharmacokinetics and Pharmacodynamics of TQA3810 TabletsCompletedNCT06431438Phase 1
• A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT06384131Phase 1
• Discovering Urinary Protein Biomarkers for Hepatocellular Carcinoma in Chronic Hepatitis B PopulationActive, not recruitingNCT06379334
• The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB PatientsActive, not recruitingNCT06357806Not applicable
• A Study of LW231 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus InfectionCompletedNCT06311734Phase 1
• Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV InfectionWithdrawnNCT06245291Phase 2
• Composite Probiotics Stabilize Lipid Metabolism in Chronic Hepatitis B Patients:A Clinical TrialCompletedNCT06221605Not applicable
• A Phase I, the Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002TerminatedNCT06162299Phase 1
• A Clinical Study of 162 in Subjects With Chronic Hepatitis B Virus InfectionTerminatedNCT06159062Phase 1
• A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis BActive, not recruitingNCT06150014Phase 1/2
• A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) PatientsCompletedNCT06115993Phase 1/2
• VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis BActive, not recruitingNCT06092333Phase 2
• Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide TherapyCompletedNCT06070051Phase 1
• Evaluation of the Effectiveness of the Complex of Carnitine Orotate and Biphenyl Dimethyl Dicarboxylate in the Adjuvant Therapy of Chronic Hepatitis D in Real Clinical Practice: a Prospective Cohort StudyWithdrawnNCT06068140
• Efficacy and Safety of Switching to Vemliver From Entecavir in Chronic Hepatitis B Patients Previously Treated With EntecavirCompletedNCT06000657Phase 4
• Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV PatientsCompletedNCT05970289Phase 2
• A Study of RBD1016 in CHB ParticipantsCompletedNCT05961098Phase 2
• Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.CompletedNCT05960240Phase 1
• Clinical Study to Evaluate the Efficacy and Safety of DA-2803 in Chronic Hepatitis B PatientsCompletedNCT05957380Phase 4
• Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis BActive, not recruitingNCT05905731Phase 1
• A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs)CompletedNCT05905458Phase 2
• Effects of Hepatic Fibrosis on Hepatic Steatosis Using the Ultrasound Attenuation Imaging in Chronic Hepatitis BCompletedNCT05871749
• Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV InfectionWithdrawnNCT05867056Phase 1
• Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104Active, not recruitingNCT05841095Phase 1/2
• A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase InhibitorsCompletedNCT05839639Phase 2
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis BCompletedNCT05828745Phase 1
• The Effectiveness and Safety of TMF in the Treatment of Chronic Hepatitis B Patients With Normal ALT.Active, not recruitingNCT05797714Not applicable
• Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis BActive, not recruitingNCT05793268Not applicable
• Study of COVID-19 Infection and Its Clinical Prognosis in Chronic Hepatitis B Patients With Antiviral TherapyStatus unknownNCT05792878
• Comparison of Hepatus and FibroScan for Evaluation of Fibrosis and SteatosisStatus unknownNCT05786963
• To Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis BTerminatedNCT05760781Phase 2
• Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis BTerminatedNCT05760703Phase 2
• The Efficacy and Safety of Tenofovir Amibufenamide to Treat Low-level Viraemia After Entecavir TreatmentStatus unknownNCT05755776
• Effect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHBCompletedNCT05753280Phase 4
• A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level ViremiaCompletedNCT05734807Phase 2
• A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine CandidateCompletedNCT05727267Phase 1
• Study on Screening, Verification and Intervention of High-risk Patients With Liver CancerStatus unknownNCT05721300Not applicable
• A Study Evaluating AHB-137 in Healthy Participants and Participants with Chronic Hepatitis BCompletedNCT05717686Phase 1
• Relationship Between MAFLD and Liver Fibrosis Progression in Patients With Chronic Hepatitis B: a Multicenter Retrospective Cohort StudyStatus unknownNCT05708560
• Hepatic Steatosis and Chronic Hepatitis B VirusCompletedNCT05678582
• A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With Chronic Hepatitis B and Hepatitis D Co-infectionTerminatedNCT05674448Phase 2
• A Prospective Study to Evaluate Peginterferon in Reducing the Incidence of HCC in CHB PatientsStatus unknownNCT05671315Not applicable
• Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 TabletsCompletedNCT05637541Phase 2
• Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 2)CompletedNCT05630820Phase 3
• Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)CompletedNCT05630807Phase 3
• Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)CompletedNCT05621304
• A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy SubjectsCompletedNCT05569941Phase 1
• Platelets Indices and Its Role to Predict Liver Fibrosis in Patients With Chronic Hepatitis B InfectionStatus unknownNCT05567614
• A Study of ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB SubjectsTerminatedNCT05561530Phase 1
• A Nomogram for Evaluating Significant Liver Fibrosis in Patients With Chronic Hepatitis B Virus InfectionCompletedNCT05560503
• A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) TreatmentWithdrawnNCT05550519Early Phase 1
• Clinical Effects of Ganshuang Combined TDF to Treat CHB and NAFLDCompletedNCT05523648Early Phase 1
• Comparing P1101 to Entecavir in Patients With HBeAg(-) Hepatitis B Under Long-term Nucleos(t)Ide Analogue TherapyStatus unknownNCT05494528Not applicable
• Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB PatientsCompletedNCT05490836Not applicable
• A Study to Evaluate the Efficacy and Safety of ZM-H1505R in Combination With ETV Compared With ETV Monotherapy in Patients With CHBStatus unknownNCT05484466Phase 2
• Prevalence of Significant Liver Fibrosis and Inflammation in Chronic HBV Infected Patients in Grey ZoneStatus unknownNCT05483049
• Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 DiabetesStatus unknownNCT05473806Phase 4
• A Multiple-dose Study in Chinese Subjects to Evaluate Safety,Tolerability,PK and PD of ZM-H1505RCompletedNCT05470829Phase 1
• Study on Clinical Program Optimization of Inactive Hepatitis B Surface Antigen (HBsAg) Carriers (IHCs)Status unknownNCT05457920Not applicable
• Inactive HBsAg Carriers (IHCs) Treated With Pegylated Interferon α2b Based Intervention TherapyCompletedNCT05451420Not applicable
• Serum Regucalcin Level and Chronic Hepatitis BCompletedNCT05435599Not applicable
• Chronic Kidney Disease Progression in Chronic Hepatitis B Patients on Tenofovir Alafenamide (TAF) Versus EntecavirActive, not recruitingNCT05423834
• A Single and Multiple Ascending Dose Study of JNJ-64457744TerminatedNCT05423106Phase 1
• A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT05414981Phase 1
• Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV InfectionActive, not recruitingNCT05410496Phase 4
• An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV TreatmentStatus unknownNCT05398393Not applicable
• Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of StudyCompletedNCT05391360Phase 1
• Antiviral Therapy for Patients With Chronic Hepatitis B InfectionStatus unknownNCT05382351Phase 2
• Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS TreatmentStatus unknownNCT05382013Phase 4
• The Study on Optimal Treatment and Clinical Outcome of Chronic Hepatitis B Patients With Inactive HypoviremiaStatus unknownNCT05357235
• The Study on Clinical Outcome and Treatment Optimization of Chronic Hepatitis B Patients With HypoviremiaStatus unknownNCT05357183
• Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in SerumCompletedNCT05355467Phase 4
• Treatment of Patients With Chronic Hepatitis B With Hepatitis B ImmunoglobulinsTerminatedNCT05345990Phase 2
• Efficacy of VTP-300 in Chronic Hepatitis B InfectionCompletedNCT05343481Phase 2
• Discontinuation of Antiviral Therapy as a Strategy to Cure Hepatitis BActive, not recruitingNCT05328427Not applicable
• Steatohepatitis in Chronic Hepatitis BCompletedNCT05317260
• The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDFCompletedNCT05313477Phase 4

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