Hepatitis B, Chronic: all 954 studies

Page 2 of 10. Open to participants first (147), then studies with results posted, then the rest; newest registration first within each.

• Population-wide Research for HBV-related Liver Diseases in Maoming CityNot yet recruitingNCT06184347
• Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis BRecruitingNCT06154278Phase 2
• Gut Microbiome in People Living With HIV and HBVNot yet recruitingNCT06130137
• Individual Nutrition Support in HBV-ACLF Patients at Nutrition RiskRecruitingNCT06128421Not applicable
• A Clinical Trial of TQA3038 Injection in Healthy Adult SubjectsRecruitingNCT06085053Phase 1
• Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected PatientsRecruitingNCT06047093Not applicable
• A Non-invasive Model to Predict Antiviral Therapy in Gray Zone of Chronic Hepatitis BNot yet recruitingNCT06041022
• Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.RecruitingNCT06023745
• Dynamic Changes of Serum HBV RNA in Chronic Hepatitis B PatientsNot yet recruitingNCT05991531
• HBsAg Declined Patients Follow-up StudyRecruitingNCT05977283
• Chronic Hepatitis B Patients With Concurrent MAFLD: Cohort Study and Exercise Intervention.Enrolling by invitationNCT05956379Not applicable
• Real-world Study Optimizing Nucleotide-analoguesRecruitingNCT05937178
• Efficacy of NA Combined With PEG-IFN-α2b in the Continuous Versus Pulsed Treatment of Patients With Chronic Hepatitis BRecruitingNCT05922306Early Phase 1
• Clinical Efficacy and Safety of Tenofovir Disoproxil Fumarate and Entcavir in Treatment of Chronic Hepatitis B Patients in Upper EgyptRecruitingNCT05874440
• Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH)RecruitingNCT05870969
• Study of Tenofovir Alafenamide in HBV-Infected Pregnant WomenRecruitingNCT05853718Phase 4
• Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis BRecruitingNCT05808374Phase 1
• A Study to Assess the Efficacy and Safety of Burfiralimab(hzVSF-v13) and OAD (Oral Antiviral Drug)RecruitingNCT05808335Phase 2
• A Study on Antiviral Treatment of Chronic Hepatitis B in ChildrenRecruitingNCT05792761Not applicable
• A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)RecruitingNCT05771402Phase 2
• A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)RecruitingNCT05769816Phase 2
• Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLDRecruitingNCT05766449
• The Effect of Metabolic Syndrome on Antiviral Response in People With Chronic Hepatitis BNot yet recruitingNCT05705141
• Clinical Outcomes of HBeAg-negative CHB Patients With Indeterminate PhaseRecruitingNCT05661786
• Tenofovir Alafenamide Switch Therapy in Chronic Hepatitis BRecruitingNCT05583006
• Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA LoadRecruitingNCT05466071
• Clinical Characteristics, Natural Outcome and Treatment Optimization of RefractoryRecruitingNCT05376124
• Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept StudyNot yet recruitingNCT05293158Not applicable
• A Prospective/Retrospective, Observational Follow-up Study of Chronic Hepatitis B With Non-alcoholic Fatty Liver Disease.RecruitingNCT05255978
• TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.RecruitingNCT05195450Not applicable
• Peginterferon Treatment Study for Inactive Chronic Hepatitis B PatientsRecruitingNCT05182463Phase 4
• Mother-to-child Transmission of HBV in ChinaRecruitingNCT05172453
• Prospective Evaluation of a Fast-track Treatment Pathway for Patients With Chronic Hepatitis B Under Primary CareRecruitingNCT04904900
• Long-term Outcomes of Anti-viral Therapies in Patients With Chronic Viral Hepatitis BRecruitingNCT04896255
• TLR-9 Adjuvanted Vaccination for Chronic Hepatitis BRecruitingNCT04843852Phase 1
• The Effectiveness and Safety of Tenofovir Alafenamide in the Treatment of Chronic Hepatitis B Patients With Mildly Elevated Alanine Aminotransferase and Significant Liver Injury.RecruitingNCT04674423Phase 4
• Combination of DPMAS and Low Volume PE for Patients With HBV Related ACLFRecruitingNCT04597164
• User-friendly HIV Testing and Counseling ServicesRecruitingNCT04585165
• A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis BRecruitingNCT04568265Phase 2
• National Cohort of Patients Co-infected with Hepatitis B and Delta VirusesRecruitingNCT04166266
• The Establishment of Korean Hepatitis B Patients CohortRecruitingNCT04139850
• Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)RecruitingNCT03792919Phase 4
• A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis BRecruitingNCT03108794
• "Real-life" Cohort Study on Patients With Chronic HBV Infection in JiangsuRecruitingNCT03097952
• A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus InfectionNot yet recruitingNCT03038802Phase 1/2
• Therapeutic Effects and Long-term Follow-up After Ending Nucleos(t)Ide Analogs Therapy in Chronic Hepatitis bRecruitingNCT02883647
• Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver DiseaseRecruitingNCT02863757
• Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis BCompletedNCT05770895Phase 1Results posted
• A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT05763576Phase 1Results posted
• A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B InfectionCompletedNCT05612581Phase 1/2Results posted
• Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B InfectionTerminatedNCT05330455Phase 1/2Results posted
• An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B ParticipantsCompletedNCT05275023Phase 2Results posted
• A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT05005507Phase 2Results posted
• Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B InfectionCompletedNCT04980482Phase 2Results posted
• Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)CompletedNCT04891770Phase 2Results posted
• A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B InfectionTerminatedNCT04820686Phase 2Results posted
• A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT04781647Phase 2Results posted
• Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT04749368Phase 2Results posted
• HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)TerminatedNCT04684914Phase 2Results posted
• Study of Sequential GSK3228836 and Peginterferon Treatment in Participants With Chronic Hepatitis B (CHB)CompletedNCT04676724Phase 2Results posted
• A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus InfectionCompletedNCT04667104Phase 2Results posted
• A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus InfectionCompletedNCT04585789Phase 2Results posted
• Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland ChinaCompletedNCT04507269Phase 2Results posted
• Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)TerminatedNCT04465916Phase 2Results posted
• A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase InhibitorsTerminatedNCT04454567Phase 2Results posted
• A Study of GSK3228836 in Participants With Chronic Hepatitis B (CHB)CompletedNCT04449029Phase 2Results posted
• A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT04439539Phase 2Results posted
• Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus InfectionCompletedNCT04423393Phase 1Results posted
• Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus InfectionCompletedNCT04412863Phase 2Results posted
• A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT04398134Phase 2Results posted
• A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis BCompletedNCT04225715Phase 2Results posted
• A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus InfectionCompletedNCT04129554Phase 2Results posted
• Chronic HBV Management for Asian AmericanCompletedNCT04082338Not applicableResults posted
• A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus InfectionCompletedNCT03982186Phase 2Results posted
• Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis BCompletedNCT03905655Phase 2Results posted
• Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B InfectionTerminatedNCT03866187Phase 1/2Results posted
• A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B PatientsTerminatedNCT03780543Phase 2Results posted
• A Study of RO7239958 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT03762681Phase 1Results posted
• Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis BCompletedNCT03672188Phase 1/2Results posted
• Study to Evaluate the Safety, Tolerability, and Antiviral Activity of Selgantolimod (Formerly GS-9688) in Viremic Adult Participants With Chronic Hepatitis B (CHB) Who Are Not Currently on TreatmentCompletedNCT03615066Phase 2Results posted
• A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)CompletedNCT03577171Phase 2Results posted
• A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B InfectionCompletedNCT03576066Phase 2Results posted
• Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis BCompletedNCT03491553Phase 2Results posted
• Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)CompletedNCT03471624Phase 4Results posted
• Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)TerminatedNCT03434353Phase 2Results posted
• An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus InfectionCompletedNCT03361956Phase 2Results posted
• A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis BCompletedNCT03258710Phase 4Results posted
• Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)CompletedNCT03180619Phase 2Results posted
• A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis BCompletedNCT03038113Phase 1Results posted
• A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3389404 in Chronic Hepatitis B (CHB) SubjectsCompletedNCT03020745Phase 2Results posted
• Safety, Tolerability, Pharmacokinetics and Antiviral Activity of IONIS-HBVRx in Treatment-Naïve Patients With Chronic HBV InfectionCompletedNCT02981602Phase 2Results posted
• Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically SuppressedCompletedNCT02979613Phase 3Results posted
• A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )CompletedNCT02964910Phase 4Results posted
• A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531CompletedNCT02956850Phase 1Results posted
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected ParticipantsCompletedNCT02952924Phase 1Results posted
• Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agentCompletedNCT02888106Phase 2Results posted
• Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis BCompletedNCT02881008Phase 1/2Results posted
• Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver TransplantCompletedNCT02862548Phase 2Results posted
• Second Stage:Open-label Study of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis BCompletedNCT02862106Phase 2Results posted
• A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access ProgramCompletedNCT02791269Phase 4Results posted

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