Hepatic Veno-Occlusive Disease clinical trials

The registry lists 23 studies for Hepatic Veno-Occlusive Disease across more than 10 countries. 3 are recruiting or about to start. 20 of them are mainly about Hepatic Veno-Occlusive Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Status

Completed: 12
Status unknown: 5
Recruiting: 2
Not yet recruiting: 1
Withdrawn: 1
Terminated: 1

Phase

Phase 2: 6
Phase 3: 4
Phase 4: 1

Where

United States: 12
Italy: 5
France: 4
United Kingdom: 3
Israel: 2
Canada: 2

Who runs them

Jazz Pharmaceuticals (4) · Children's Mercy Hospital Kansas City (4) · Maastricht University Medical Center (1) · Central Hospital, Nancy, France (1) · Indiana University (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Loyola University (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1)

What is being tested here

Drugs under test in Hepatic Veno-Occlusive Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Defibrotide	1	4	6
S-Adenosylmethionine	1	0	1
Acetylcysteine	0	0	1
Glutamine	0	0	1

Coming up

0phase 3 studies under way

2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Dec 2026Cell Free DNA Profiling As a Tool to Monitor Clinically-Relevant Events in Allogeneic Hematopoietic Stem Cell Transplantation · University of Turin, Italy
Aug 2027Defibrotide Dose-escalation for SOS Post-HSCT · New York Medical College

Who these studies take

Of the 2 Hepatic Veno-Occlusive Disease studies recruiting now, 1 (50%) set no upper age limit and 1 (50%) stop at 75 or younger. 1 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 2
Age	Women	Men
10	1 (50%)	1 (50%)
18	2 (100%)	2 (100%)
30	2 (100%)	2 (100%)
40	2 (100%)	2 (100%)
50	2 (100%)	2 (100%)
65	2 (100%)	2 (100%)
75	2 (100%)	2 (100%)
85	1 (50%)	1 (50%)

Across all 23 studies, recruiting or not: 43% stop at 75 or younger and 30% at 65; 70% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 23 of 23. search them.