Hearing Loss, Sudden clinical trials
The registry lists 66 studies for Hearing Loss, Sudden across more than 10 countries. 25 are recruiting or about to start. 49 of them are mainly about Hearing Loss, Sudden (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Eye & ENT Hospital of Fudan University (6) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (5) · Frequency Therapeutics (4) · Tel-Aviv Sourasky Medical Center (3) · Andrea Vambutas (2) · Yuzuncu Yıl University (2) · Assiut University (2) · Peking University People's Hospital (2)
What is being tested here
Drugs under test in Hearing Loss, Sudden studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Hyaluronic Acid | 1 | 0 | 3 |
| Methylprednisolone | 1 | 1 | 3 |
| Dexamethasone | 1 | 0 | 2 |
| Hydroxychloroquine | 1 | 0 | 1 |
| Topiramate | 1 | 0 | 1 |
| FX-322 | 0 | 0 | 4 |
| Interleukin 1 Receptor Antagonist Protein | 0 | 0 | 2 |
| Prednisone | 0 | 0 | 2 |
| NS101 | 0 | 0 | 1 |
| SENS-401 | 0 | 1 | 1 |
Drug classes tested here Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Nov 2026Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss · Dan Bing
- Dec 2026Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss · Chang Gung Memorial Hospital
- Aug 2027Intracochlear Injection of Glucocorticoid · Eye & ENT Hospital of Fudan University
- Oct 2027Intratympanic Injection of Dexamethasone With Hyaluronic Acid in Treatment of Sudden Sensorineural Hearing Loss · Assiut University
- Nov 2027Yiyuancong for the Treatment of Sudden Sensorineural Hearing Loss · Guangdong Provincial People's Hospital
Who these studies take
Of the 10 Hearing Loss, Sudden studies recruiting now, 3 (30%) set no upper age limit and 5 (50%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 8 (80%) | 8 (80%) |
| 30 | 10 (100%) | 10 (100%) |
| 40 | 10 (100%) | 10 (100%) |
| 50 | 10 (100%) | 10 (100%) |
| 65 | 8 (80%) | 8 (80%) |
| 75 | 5 (50%) | 5 (50%) |
| 85 | 4 (40%) | 4 (40%) |
Across all 66 studies, recruiting or not: 50% stop at 75 or younger and 24% at 65; 14% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Results posted1
- Oral Statins and Protection From Hearing LossOct 29, 2026NCT04826237
Newly registered2
- Autologous Circulating Extracellular Vesicles for Total-Type Sudden Sensorineural Hearing LossOct 16, 2026NCT07878559
- Expanded Access Protocol for SPI-1005Oct 14, 2026NCT07873281
Studies
Recruiting first, then most recently updated. Showing 50 of 66. Browse all 66 → or search them.
- Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing LossRecruitingNCT06467526Phase 21 country
- Autologous Circulating Extracellular Vesicles for Total-Type Sudden Sensorineural Hearing LossNot yet recruitingNCT07878559Phase 31 country
- Efficacy and Safety of Intracochlear Injection of Glucocorticoid Through the Round Window Membrane in Patients With Profound or Complete Sudden Sensorineural Hearing LossNot yet recruitingNCT07814677Phase 21 country
- Comparison of the Effectiveness of Oral and Intratympanic Corticosteroid Treatments in Patients Diagnosed With Sudden Sensorineural Hearing LossRecruitingNCT06968507Phase 41 country
- CGM-guided Patch Pump vs Basal-Bolus Injection for Steroid-Induced Hyperglycemia in Sudden Sensorineural Hearing Loss: SHIP TrialNot yet recruitingNCT07652528Not applicable
- Acupuncture Therapy for Sudden Sensorineural Hearing LossRecruitingNCT07575334Not applicable1 country
- Trans-round Window Membrane Intracochlear SteroidNot yet recruitingNCT07540728Phase 21 country
- Yiyuancong for the Treatment of Sudden Sensorineural Hearing LossRecruitingNCT07505667Not applicable1 country
- Study on the Safety and Efficacy of Intratympanic Injection of Small Extracellular Vesicles Derived From Mesenchymal Stem Cells in Severe and Profound Sudden Sensorineural Hearing LossNot yet recruitingNCT07404709Phase 1/21 country
- Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing LossEnrolling by invitationNCT07472023Early Phase 11 country
- Effect of Aspirin and Folic Acid for Sudden Sensorineural Hearing LossNot yet recruitingNCT07113158Phase 31 country
- Effectiveness of Integrative Medical Treatment in Sudden Hearing LossRecruitingNCT07235488Not applicable1 country
- Intracochlear Injection of GlucocorticoidNot yet recruitingNCT07134075Phase 21 country
- Evaluation of Oral Corticosteroid Therapy in Idiopathic Sudden Unilateral Hearing Loss.Not yet recruitingNCT07067801Phase 31 country
- 'Inner Ear Support' Oral Capsule in Patients With Sudden Sensorineural Hearing LossNot yet recruitingNCT06997406Not applicable1 country
- Effect of Hyperbaric Oxygen Therapy(HBOT) on Patients With Sudden Sensorineural Hearing Loss(SSNHL) and Coagulation FunctionNot yet recruitingNCT068192021 country
- Sudden Sensorineural Hearing Loss in Wonju Severance Christian HospitalRecruitingNCT054749631 country
- Intratympanic Injection of Dexamethasone With Hyaluronic Acid in Treatment of Sudden Sensorineural Hearing LossNot yet recruitingNCT06878599Phase 41 country
- Autologous Blood Monocyte Vesicles for the Treatment of Sudden DeafnessNot yet recruitingNCT06707389Early Phase 1
- The Development of Tinnitus in Patients With SSNHL: Insights From fMRI and MetabolomicsEnrolling by invitationNCT063551021 country
- Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing LossNot yet recruitingNCT06365775
- Evaluation of the Diagnostic and Prognostic Efficacy of MRI in Acute Sensorineural Hearing Loss and Ménière's DiseaseRecruitingNCT062781291 country
- The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing LossRecruitingNCT05403229Phase 21 country
- The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With TinnitusRecruitingNCT05964725Not applicable1 country
- The Effect of PAP on ISSHL Comorbided With OSARecruitingNCT04192656Phase 41 country
- A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL PatientsCompletedNCT06249919Phase 1/21 country
- Oral Statins and Protection From Hearing LossTerminatedNCT04826237Phase 41 country
- Expanded Access Protocol for SPI-1005Temporarily not availableNCT07873281
- Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing LossWithdrawnNCT06437054Phase 1/2
- Use of Vibration Anesthesia Device in Intratympanic InjectionsCompletedNCT06885723Not applicable1 country
- Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing LossCompletedNCT04766853Phase 1/21 country
- High Dose Oral Steroids in Sudden Sensorineural Hearing LossWithdrawnNCT03255473Phase 21 country
- Correlation MRI - Paraclinical Examination in Sudden Deafness Associated With VertigoCompletedNCT056614871 country
- Single-sided Deafness and Cochlear ImplantationCompletedNCT050529441 country
- Small Sample,Unicentric,Randomized, Controlled Clinical Study of Coenzyme I for Injection in the Treatment of Sudden Sensorineural Hearing LossStatus unknownNCT05849519Early Phase 11 country
- FX-322 in Adults With Stable Sensorineural Hearing LossCompletedNCT04120116Phase 21 country
- FX-322 in Adults With Acquired Sensorineural Hearing LossCompletedNCT05086276Phase 21 country
- Assessment of The Efficacy of Intratympanic Platelet Rich Plasma for Treatment of Sensorineural Hearing Loss.Status unknownNCT05786378Phase 2/31 country
- Efficacy of SENS 401 in Subjects With Severe or Profound Sudden Sensorineural Hearing LossCompletedNCT03603314Phase 2/310 countries
- Effect of Ultrasound-guided Stellate Ganglion Block Combined With Facial Nerve and Glossopharyngeal Nerve Block on the Treatment of Sudden DeafnessStatus unknownNCT05623384Not applicable1 country
- Speech Perception Impairment Follow Complete Recovery of Sudden Sensorineural Hearing LossStatus unknownNCT05608161
- Prognosis of Vestibular Dysfunction in Patients With Idiopathic Sudden Sensorineural Hearing LossCompletedNCT039515841 country
- Establishment of a Trans-round Window Inner Ear Continuous Drug Delivery System for the Treatment of Severe-to-profound Sudden Sensorineural Hearing LossStatus unknownNCT05455398Not applicable1 country
- FX-322 in Adults With Age-Related Sensorineural Hearing LossCompletedNCT04601909Phase 11 country
- FX-322 in Adults With Severe Sensorineural Hearing LossCompletedNCT04629664Phase 11 country
- Phase I Clinical Study of HY01 in PatientsStatus unknownNCT04961099Phase 11 country
- What is the Tympanic Membrane Healing Time After Insertion of a Gelfoam PE Tube?CompletedNCT04902963Not applicable
- Blood Markers in Adult Patients With Sudden Sensorineural Hearing Loss (SSNHL)CompletedNCT039194741 country
- The Effect of Patient's Position After Intra-tympanic Injection on the Amount of Fluid in the Middle EarStatus unknownNCT04449848Not applicable
- OSA and Sudden Sensorineural Hearing LossCompletedNCT03747874Not applicable1 country