Germinoma clinical trials
The registry lists 16 studies for Germinoma across more than 10 countries. 6 are recruiting or about to start. 3 of them are mainly about Germinoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Seminoma too: 76 studies, 20 open.
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A study of drug A after surgery for early breast cancer
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Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Children's Oncology Group (3) · National Cancer Institute (NCI) (3) · Harry T Whelan, MD (2) · Alliance for Clinical Trials in Oncology (1) · Samsung Medical Center (1) · National Cancer Center, Korea (1) · N.N. Petrov National Medical Research Center of Oncology (1) · Cheng sen (1)
What is being tested here
Drugs under test in Germinoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Carboplatin | 0 | 1 | 2 |
| Etoposide | 0 | 1 | 2 |
| Tremelimumab | 0 | 0 | 1 |
| Cisplatin | 0 | 1 | 1 |
| Etoposide phosphate | 0 | 1 | 1 |
| Dihematoporphyrin Ether | 0 | 0 | 1 |
| Cyclophosphamide | 0 | 0 | 1 |
| Bleomycin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Nov 2026Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors · Memorial Sloan Kettering Cancer Center
- Jun 2027Molecular Epidemiology of Pediatric Germ Cell Tumors · Children's Oncology Group
Who these studies take
Of the 5 Germinoma studies recruiting now, 4 (80%) set no upper age limit and 1 (20%) stop at 75 or younger. 3 (60%) take children under 18. 0 (0%) are for women only and 1 (20%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (60%) | 3 (60%) |
| 18 | 4 (80%) | 5 (100%) |
| 30 | 3 (60%) | 4 (80%) |
| 40 | 3 (60%) | 4 (80%) |
| 50 | 3 (60%) | 4 (80%) |
| 65 | 3 (60%) | 4 (80%) |
| 75 | 3 (60%) | 4 (80%) |
| 85 | 3 (60%) | 4 (80%) |
Across all 16 studies, recruiting or not: 56% stop at 75 or younger and 50% at 65; 69% take children; 0% are for women only and 13% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 16 of 16. search them.
- Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncologyRecruitingNCT046484621 country
- A Study of Lower Radiotherapy Dose to Treat Children With CNS GerminomaRecruitingNCT06368817Phase 23 countries
- Safety and Efficacy of Vertebral Body-Sparing Craniospinal Irradiation With Proton Therapy in Pediatric TumorsNot yet recruitingNCT07589361
- Molecular Epidemiology of Pediatric Germ Cell TumorsRecruitingNCT055640261 country
- High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell TumorsRecruitingNCT06418789Phase 21 country
- Development of Asian Consortium for Data Collection and Clinical Trial of CNS TumorsRecruitingNCT059826911 country
- Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System TumorsCompletedNCT014452881 country
- China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial AneurysmActive, not recruitingNCT078091781 country
- Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell TumorsActive, not recruitingNCT03158064Phase 21 country
- Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell TumorsActive, not recruitingNCT02375204Phase 312 countries
- Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell TumorsCompletedNCT01602666Phase 25 countries
- Photodynamic Therapy (PDT) For Recurrent High Grade GliomasTerminatedNCT01966809Phase 21 country
- Photodynamic Therapy (PDT) for Recurrent Pediatric Brain TumorsCompletedNCT01682746Phase 11 country
- Chemotherapy Plus Reduced Radiotherapy in Intracranial GerminomaStatus unknownNCT02782754Phase 21 country
- Sunitinib in Treating Young Patients With Refractory Solid TumorsCompletedNCT00387920Phase 12 countries
- Combination Chemotherapy in Treating Young Patients With Advanced Solid TumorsCompletedNCT00281944Phase 11 country