Gastrointestinal Stromal Tumors: all 345 studies

Page 1 of 4. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.

• A Legacy Study in Participants With Gastrointestinal Stromal Tumors (GIST)Not yet recruitingNCT07843641Phase 2
• Individual Patient Expanded Access for Velzatinib (GSK6042981) in Patients With Gastrointestinal Stromal Tumours With KIT MutationsAvailableNCT07825701
• Hyperpolarized MRI for GIST on ImatinibNot yet recruitingNCT07724626
• LRG GIST Patient RegistryRecruitingNCT07697248
• A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and PimitespibRecruitingNCT07689201Phase 2
• Clinical Utility of ctDNA in Detecting Resistance Mechanisms and Delivering Precision Medicine to Cancer PatientsRecruitingNCT07673861Not applicable
• Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal TumorsNot yet recruitingNCT07647068Phase 2
• Study of DCC-2618 in Patients With GIST After at Least 3 Prior TreatmentsRecruitingNCT07618377Phase 1
• A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)RecruitingNCT07585266Phase 3
• A Novel Two-Tooth Clip for ESD and EFTR of GISTRecruitingNCT07581977Not applicable
• Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard TreatmentRecruitingNCT07559864Phase 2
• Mesenteric Vascular Preconditioning Combined With Laparoscopic and Endoscopic Cooperative Surgery for Submucosal Tumor at the Gastroesophageal JunctionEnrolling by invitationNCT07550582Phase 2
• Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational StudyRecruitingNCT07522762
• PH 2 Pemigatinib in SDH-deficient GISTRecruitingNCT07434843Phase 2
• KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)RecruitingNCT07406633Phase 2
• Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)RecruitingNCT07379047Phase 2/3
• A Comprehensive, Multinational GIST RegistryNot yet recruitingNCT07273045
• A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib TherapyRecruitingNCT07218926Phase 3
• Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal TumorRecruitingNCT07171203Phase 1
• DESTINY-PANTUMOUR04RecruitingNCT07124000
• Resistance Profiling Using Functional Imaging and Next Generation Sequencing in Refractory Gastrointestinal Stomal Tumors (GIST)Not yet recruitingNCT07109024
• CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled StudyNot yet recruitingNCT07106411
• Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor DiagnosisRecruitingNCT07078136
• An International Study on Pediatric Patients With Rare Tumors.RecruitingNCT07072143
• Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal TumorsAvailableNCT06948955
• Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic SurgeryRecruitingNCT06926374Not applicable
• A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-KitRecruitingNCT06805825Phase 1
• A Study of Regorafenib Combined With Envafolimab for Metastatic Gastrointestinal Stromal Tumors With Kit Gene Exon 17 Mutation That Failed Standard TreatmentNot yet recruitingNCT06772233Phase 2
• A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)RecruitingNCT06760819Phase 2
• A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)RecruitingNCT06655246Phase 1
• A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)RecruitingNCT06630234Phase 1/2
• Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT06523582
• Evaluate the Efficacy and Safety of Radiotherapy Combined With Ripretinib in the Treatment of Unresectable Advanced GISTRecruitingNCT06507683Not applicable
• The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients with Advanced GISTsRecruitingNCT06431451
• GIST Oral Paclitaxel(Liporaxel)RecruitingNCT06326346Phase 2
• Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GISTNot yet recruitingNCT05970900Phase 3
• A Cohort Study on the Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal TumorsRecruitingNCT05938309
• Rivoceranib Plus Paclitaxel in Patients With Gastrointestinal Stromal TumorRecruitingNCT05905887Phase 2
• Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GISTRecruitingNCT05751733Not applicable
• The Efficacy and Safety of Temozolomide in SDH-deficient GISTRecruitingNCT05661643Phase 2
• A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF AlterationsRecruitingNCT05503797Phase 2
• Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote MonitoringRecruitingNCT05500391Phase 2
• Imatinib TDM in GISTRecruitingNCT05493215Phase 2
• A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal TumorsRecruitingNCT05464875
• Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRARecruitingNCT05461664
• Endoscopic Ultrasound Radiofrequency Ablation for GISTsRecruitingNCT05453292Not applicable
• Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: a Real-world StudyRecruitingNCT05440357
• Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRDRecruitingNCT05408897
• 5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High RiskRecruitingNCT05385549Phase 2
• ctDNA-Guided Sunitinib And Regorafenib Therapy for GISTRecruitingNCT05366816Phase 2
• (Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal TumorsRecruitingNCT05208047Phase 3
• Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)RecruitingNCT05009927Phase 2
• Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal TumorsRecruitingNCT04933669Phase 2
• Liver Transplantation for Unresectable GIST Liver MetastasesNot yet recruitingNCT04825470Not applicable
• Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic AnalysisRecruitingNCT04557969
• Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORKRecruitingNCT04181970
• Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable SiteRecruitingNCT03716089
• A Study of HQP1351 in Patients With GIST or Other Solid TumorsRecruitingNCT03594422Phase 1
• Integrated Cancer Repository for Cancer ResearchRecruitingNCT02012699
• Clinical & Pathological Studies of Upper Gastrointestinal CarcinomaRecruitingNCT01048281
• A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)TerminatedNCT05160168Phase 1/2Results posted
• Study for Patients Previously Treated in Avapritinib Clinical TrialsCompletedNCT04825574Phase 4Results posted
• A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With ImatinibCompletedNCT04633122Phase 2Results posted
• A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)CompletedNCT04282980Phase 2Results posted
• DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)TerminatedNCT04276415Phase 1Results posted
• A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With ImatinibActive, not recruitingNCT03673501Phase 3Results posted
• Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)CompletedNCT03556384Phase 2Results posted
• (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GISTCompletedNCT03465722Phase 3Results posted
• Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer TherapiesCompletedNCT03353753Phase 3Results posted
• Epacadostat and Pembrolizumab in Patients With GISTTerminatedNCT03291054Phase 2Results posted
• A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney CancerTerminatedNCT03165721Phase 2Results posted
• Efficacy of Ferric Carboxymaltose in Gastrointestinal Stromal Tumor (GIST) Patients With Iron Deficiency Anemia (IDA) Receiving Systemic TherapyTerminatedNCT02949947Phase 2Results posted
• (NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid TumorsCompletedNCT02508532Phase 1Results posted
• Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by SurgeryCompletedNCT02500797Phase 2Results posted
• A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid TumorsTerminatedNCT02452424Phase 1/2Results posted
• CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid TumorsCompletedNCT02401815Phase 1/2Results posted
• BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)CompletedNCT02257541Phase 1/2Results posted
• Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GISTCompletedNCT02164240Phase 1Results posted
• Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal TumorsCompletedNCT02015065Phase 2Results posted
• Efficacy and Safety of PD-0332991 in Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and SunitinibCompletedNCT01907607Phase 2Results posted
• A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal TumorCompletedNCT01874665Phase 2Results posted
• Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib TreatmentCompletedNCT01863745Phase 2Results posted
• Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy NeedleCompletedNCT01769248Not applicableResults posted
• Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored StudyCompletedNCT01735955Phase 4Results posted
• Linsitinib in Treating Patients With Gastrointestinal Stromal TumorsCompletedNCT01560260Phase 2Results posted
• Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to ImatinibCompletedNCT01478373Phase 2Results posted
• Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258CompletedNCT01440959Phase 2Results posted
• Study of Hsp90 Inhibitor AUY922 for the Treatment of Patients With Refractory Gastrointestinal Stromal TumorCompletedNCT01404650Phase 2Results posted
• A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal TumorCompletedNCT01396148Phase 2Results posted
• Pazopanib in Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors (GIST)TerminatedNCT01391611Phase 2Results posted
• A Study of Olaratumab (IMC-3G3) in Previously Treated Participants With Unresectable and/or Metastatic Gastrointestinal Stromal TumorsTerminatedNCT01316263Phase 2Results posted
• Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib.CompletedNCT01289028Phase 3Results posted
• Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal TumorsCompletedNCT01275222Phase 1/2Results posted
• Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)CompletedNCT01271712Phase 3Results posted
• Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1/2Results posted
• Rechallenge of Imatinib in GIST Having no Effective Treatment: RIGHTCompletedNCT01151852Phase 3Results posted
• Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal TumorCompletedNCT01068769Phase 2Results posted
• A Study Evaluating STA-9090 in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST)CompletedNCT01039519Phase 2Results posted
• Advanced Gastrointestinal Endoscopic ImagingTerminatedNCT01034670Not applicableResults posted
• Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) PatientsTerminatedNCT01031628Phase 3Results posted

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