Frontotemporal Dementia: all 261 studies

Page 2 of 3. Open to participants first (75), then studies with results posted, then the rest; newest registration first within each.

• Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT MutationsCompletedNCT02676843Phase 2Results posted
• Arimoclomol Prospective Study in Participants Diagnosed With Niemann-Pick Disease Type CCompletedNCT02612129Phase 2/3Results posted
• tDCS Intervention in Primary Progressive AphasiaCompletedNCT02606422Not applicableResults posted
• Efficacy of Web-Based Social-Cognitive Interventions in Right Hemisphere Stroke and Frontotemporal DementiaCompletedNCT02506036Not applicableResults posted
• Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)TerminatedNCT02245568Phase 3Results posted
• Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1CompletedNCT02124083Phase 1/2Results posted
• Imaging Characteristics of Florbetapir 18F in Patients With Frontotemporal Dementia, Alzheimer's Disease and Normal Controls.CompletedNCT01890343Phase 2Results posted
• Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl CysteineCompletedNCT00975689Phase 1/2Results posted
• Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of MetabolismTerminatedNCT00668564Phase 2Results posted
• Effects of Tolcapone on Frontotemporal DementiaCompletedNCT00604591Phase 2Results posted
• Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal DementiaCompletedNCT00545974Phase 4Results posted
• A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's DiseaseCompletedNCT07307872
• Clinical Study of Neflamapimod in Patients With Primary Progressive AphasiaActive, not recruitingNCT07033481Phase 2
• Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical ApproachesActive, not recruitingNCT06856850
• Music, Social Attention, and DementiaActive, not recruitingNCT06768996Not applicable
• Predict to Prevent PGRN DiseaseWithdrawnNCT06711510Not applicable
• Study in Asymptomatic GRN-FTD Patients to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001CompletedNCT06705192Phase 1
• Neurological Soft Signs in Neurodegenerative DementiasCompletedNCT06354933
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy ParticipantsCompletedNCT06226064Phase 1
• Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's DiseaseCompletedNCT06224920
• Communication Bridge Pilot StudyActive, not recruitingNCT06211374Not applicable
• Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register StudyActive, not recruitingNCT06209515
• Home-Based Exercise in Primary Progressive Aphasia (HEPPA)CompletedNCT06181500Not applicable
• Continuation Study for LatozinemabTerminatedNCT06111014Phase 3
• A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) SyndromesActive, not recruitingNCT05956834
• Investigation of the Effect of Preoperative Bowel Cleansing on Postoperative Cognitive ImpairmentCompletedNCT05942404Not applicable
• Auditory Beat Stimulation and Behavioural Variant of Frontotemporal DementiaCompletedNCT05917886Not applicable
• SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and DementiaCompletedNCT05885620Not applicable
• Long-term Effect of TMS in Primary Progressive AphasiaCompletedNCT05842473Not applicable
• Digital Smartwatch Measurements as Potential Biomarkers for Remote Disease Tracking in ALSWithdrawnNCT05830214
• A Study of Caregiver Connections Via Technology in DementiaCompletedNCT05779839Not applicable
• Nabilone for Agitation in Frontotemporal DementiaTerminatedNCT05742698Phase 2
• The Care Ecosystem Consortium Effectiveness StudyCompletedNCT05669365Not applicable
• Autobiographical SpecificityCompletedNCT05642351
• Identification of Graphic Markers of Neurocognitive Disorders (MG)CompletedNCT05537688
• Better Living With Non-memory-led DementiaCompletedNCT05525377Not applicable
• Group-Based Telehealth Music Therapy Intervention for Patients With Dementia: A Pilot StudyCompletedNCT05508646Not applicable
• A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of DementiaWithdrawnNCT05497817Not applicable
• An Open-Label, Expanded Access Protocol of LAM-002A in C9ORF72-Associated Frontotemporal Dementia (FTD)No longer availableNCT05483322
• The Safety and The Efficacy Evaluation of ET-STEM in Patients With Frontotemporal DementiaActive, not recruitingNCT05315661Phase 1
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)Active, not recruitingNCT05262023Phase 1/2
• Tau Protein and SV2a Imaging in Patients With Tau Protein-related DiseasesStatus unknownNCT05260151
• Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 PathologyActive, not recruitingNCT05184569Phase 1
• Epidemiological Study in FRONtoTemporal DementiaCompletedNCT05075187
• Olfactory Deficits in Neurologic DiseaseCompletedNCT05019014
• WeCareAdvisor Study for Caregivers of People Living With DementiaCompletedNCT05012410Not applicable
• Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related DementiasStatus unknownNCT05004558Not applicable
• A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTDCompletedNCT04993755Phase 2
• Mindfulness-Based Stress Reduction in Dementia CaregiversCompletedNCT04977245Not applicable
• Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric DisordersCompletedNCT04939818
• Dopaminergic Therapy for Frontotemporal Dementia PatientsCompletedNCT04937452Phase 2
• Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)TerminatedNCT04931862Phase 1/2
• EEG and TMS-based Biomarkers of ALS, MS and FTDStatus unknownNCT04918251
• tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility StudyWithdrawnNCT04883229Not applicable
• Treatment for Speech and Language in Primary Progressive AphasiaActive, not recruitingNCT04881617Not applicable
• Phenotype, Genotype and Biomarkers 2Active, not recruitingNCT04875416
• Phase 3 Study to Evaluate Intravenous Trappsol(R) Cyclo(TM) in Pediatric and Adult Patients With Niemann-Pick Disease Type C1Active, not recruitingNCT04860960Phase 3
• Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept StudyActive, not recruitingNCT04828434Not applicable
• A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 GenesActive, not recruitingNCT04747431Phase 1/2
• Clinical Evaluation of Florbetapir in Primary Progressive AphasiaCompletedNCT04726527
• Florbetaben PET Imaging in PPACompletedNCT04720001
• Assessment of Empathetic Process by Scanpath Study of an ArtworkCompletedNCT04665622Not applicable
• Metacognition in Semantic Dementia: Comparison With Alzheimer's DiseaseCompletedNCT04597827
• Neurofilament Surveillance Project (NSP)Active, not recruitingNCT04516499
• Palmitoylethanolamide Combined With Luteoline in Frontotemporal Dementia Patients. A Randomized Controlled TrialCompletedNCT04489017Phase 2
• Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive AphasiaWithdrawnNCT04486586Not applicable
• Health Insurance Literacy and Challenges in Accessing Health Services in Niemann-PickCompletedNCT04469894
• rTMS Treatment of Primary Progressive AphasiaCompletedNCT04431401Not applicable
• Feasibility of Passive Data Collection in Dementia Subjects With AgitationCompletedNCT04413851
• PPA Tele-Savvy: A Pilot Study of an Online Intervention for Caregivers of Persons Living With PPACompletedNCT04412083Not applicable
• Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)Active, not recruitingNCT04408625Phase 1/2
• Can Magnetic Brain Stimulation Improve Language Function in Primary Progressive AphasiaStatus unknownNCT04193267Not applicable
• The Effects of a Multimodal Approach for the Treatment of PPACompletedNCT04187391Not applicable
• The Music, Sleep and Dementia StudyCompletedNCT04157244Not applicable
• The Ontario Neurodegenerative Disease Research InitiativeCompletedNCT04104373
• Voices Of Individuals: Challenges and Experiences Of bvFTDCompletedNCT04060082
• Network Modulation in Alzheimer's DiseaseCompletedNCT04045990Not applicable
• Connectomics in Psychiatric ClassificationCompletedNCT03967535
• RHAPSODY-plus: Online Counseling for Family Caregivers of Patients With Young Onset DementiaCompletedNCT03923517Not applicable
• TRIAL READY (Clinical Trial Readiness)Active, not recruitingNCT03912987
• Open-Label Study of Long-Term Safety and Efficacy of Intravenous Trappsol Cyclo (HPβCD) in Niemann-Pick Disease Type CStatus unknownNCT03893071Phase 1
• Induced Pluripotent Stem Cells for Niemann Pick DiseaseCompletedNCT03883750
• Multimodal Ocular Imaging in NeurodegenerationCompletedNCT03699644
• BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TESTerminatedNCT03658135Phase 1
• A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) MutationCompletedNCT03636204Phase 1
• 18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal ControlsCompletedNCT03625128Early Phase 1
• Transcranial Magnetic Stimulation in Primary Progressive AphasiaCompletedNCT03580954Not applicable
• Human CNS Tau Kinetics in TauopathiesCompletedNCT03545126
• Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the BrainCompletedNCT03510572Early Phase 1
• Evaluation of a Transcranial Stimulation With Direct Current on Language Disorders in Semantic DementiaStatus unknownNCT03481933Not applicable
• Cognitive Impairement In Frontotemporal DementiaCompletedNCT03452956
• rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled TrialWithdrawnNCT03448133Not applicable
• rTMS as a Treatment for PPACompletedNCT03406429Early Phase 1
• Tau PET Imaging in Atypical DementiasCompletedNCT03283449Phase 1
• Intranasal Oxytocin for Frontotemporal DementiaActive, not recruitingNCT03260920Phase 2
• A 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive AphasiaStatus unknownNCT03174886Phase 1
• Transcranial Magnetic Stimulation in Nonfluent/Agrammatic Variant Primary Progressive AphasiaTerminatedNCT03153540Not applicable
• Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural NetworksCompletedNCT03153371
• Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)CompletedNCT03088956
• More Than a Movement Disorder: Applying Palliative Care to Parkinson's DiseaseCompletedNCT03076671Not applicable

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