Esthesioneuroblastoma, Olfactory clinical trials
The registry lists 75 studies for Esthesioneuroblastoma, Olfactory across more than 10 countries. 11 are recruiting or about to start. 9 of them are mainly about Esthesioneuroblastoma, Olfactory (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
National Cancer Institute (NCI) (14) · Memorial Sloan Kettering Cancer Center (5) · Alliance for Clinical Trials in Oncology (4) · Vanderbilt-Ingram Cancer Center (4) · Case Comprehensive Cancer Center (3) · University of Arizona (2) · M.D. Anderson Cancer Center (2) · Vanderbilt University (2)
What is being tested here
Drugs under test in Esthesioneuroblastoma, Olfactory studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cisplatin | 1 | 0 | 5 |
| Etoposide | 1 | 0 | 3 |
| Gemcitabine | 1 | 0 | 3 |
| Cyclophosphamide | 1 | 0 | 2 |
| Zanzalintinib | 1 | 0 | 1 |
| Enasidenib | 1 | 0 | 1 |
| AMG 757 | 1 | 0 | 1 |
| Lead PB-212 | 1 | 0 | 1 |
| Olaparib | 1 | 0 | 1 |
| Lutetium Lu 177 dotatate | 1 | 0 | 1 |
Drug classes tested here Antimetabolites 1 open · Tyrosine kinase inhibitors (TKIs) 1 open · Alkylating agents 1 open · Antimitotic agents 7 · Angiogenesis inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Long-Term Longitudinal QoL in Patients Undergoing EEA · Ohio State University
- Mar 2027Efficacy and Safety of Induction Chemotherapy for Olfactory Neuroblastoma (ESICON) · Hongmeng Yu
Who these studies take
Of the 11 Esthesioneuroblastoma, Olfactory studies recruiting now, 5 (45%) set no upper age limit and 1 (9%) stop at 75 or younger. 3 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (27%) | 3 (27%) |
| 18 | 11 (100%) | 11 (100%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 10 (91%) | 10 (91%) |
| 65 | 10 (91%) | 10 (91%) |
| 75 | 10 (91%) | 10 (91%) |
| 85 | 10 (91%) | 10 (91%) |
Across all 75 studies, recruiting or not: 4% stop at 75 or younger and 3% at 65; 9% take children; 1% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 75. Browse all 75 → or search them.
- A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory NeuroblastomaRecruitingNCT07527169Phase 21 country
- Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base TumorsRecruitingNCT06176989Phase 21 country
- 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.RecruitingNCT04081701Phase 41 country
- A Natural History Study of Children and Adults With Olfactory NeuroblastomaRecruitingNCT047552051 country
- Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing TumorsRecruitingNCT06814496Phase 1/21 country
- [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersRecruitingNCT06479811Phase 11 country
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy ParticipantsRecruitingNCT008986381 country
- Recurrent/Metastatic Olfactory Neuroblastoma: Evaluating the Efficacy and Safety of NivolumabRecruitingNCT07100704Phase 21 country
- An International Study on Pediatric Patients With Rare Tumors.RecruitingNCT070721431 country
- Efficacy and Safety of Induction Chemotherapy for Olfactory Neuroblastoma (ESICON)RecruitingNCT06255210Phase 21 country
- Long-Term Longitudinal QoL in Patients Undergoing EEAActive, not recruitingNCT040879021 country
- Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).CompletedNCT05012098Phase 21 country
- A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal PassagesCompletedNCT03274414Phase 21 country
- A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory NeuroblastomaWithdrawnNCT06308575Phase 2
- Intensity-Modulated or Proton Radiation Therapy for Sinonasal MalignancyActive, not recruitingNCT01586767Not applicable1 country
- Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerCompletedNCT00002520Not applicable1 country
- Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck CancerCompletedNCT00470496Phase 11 country
- Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck CancerCompletedNCT00006799Phase 31 country
- GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck CancerCompletedNCT00293462Phase 31 country
- Esthesioneuroblastoma: Outcomes After TreatmentWithdrawnNCT025801361 country
- Liposomal Lurtotecan Plus Cisplatin in Treating Patients With Advanced or Metastatic Solid TumorsCompletedNCT00006036Phase 11 country
- 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis TherapyCompletedNCT01806675Phase 1/21 country
- MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck CancerCompletedNCT009840741 country
- Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 11 country
- Gemcitabine and Doxorubicin in Treating Patients With Recurrent or Progressive Head and Neck CancerCompletedNCT00509665Phase 21 country
- Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without ChemotherapyCompletedNCT01156142Phase 31 country
- Studying DNA in Tissue Samples From Caucasian and African-American Cancer Patients Who Received Docetaxel on Clinical Trial CLB-9871CompletedNCT01015963
- S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid TumorsWithdrawnNCT00937417Phase 1
- High-dose ICE With AmifostineCompletedNCT00003657Phase 21 country
- Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck CancerCompletedNCT00002533Phase 2/31 country
- Oxaliplatin and Capecitabine in Treating Patients With Relapsed or Metastatic Head and Neck CancerCompletedNCT00448552Phase 21 country
- Docetaxel in Treating Patients With Solid TumorsCompletedNCT00003565Phase 23 countries
- Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By SurgeryWithdrawnNCT00041171Phase 3
- Head & Neck Cancer Survivorship: Physical and Functional StatusCompletedNCT007518161 country
- Pemetrexed Disodium and Docetaxel in Treating Patients With Advanced Solid TumorsCompletedNCT01172028Phase 11 country
- Collecting and Storing Tissue Samples From Patients With Head and Neck CancerCompletedNCT008983002 countries
- Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck CancerCompletedNCT00415025
- Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal CancerCompletedNCT00397384Phase 11 country
- Vaccine Therapy in Treating Patients With Advanced or Recurrent CancerCompletedNCT00019110Phase 11 country
- Customized Headrest or Standard Headrest in Holding Patients Still While Undergoing Radiation Therapy for Head and Neck CancerCompletedNCT00973947Not applicable1 country
- Indium In 111 Pentetreotide in Treating Patients With Refractory CancerTerminatedNCT00002947Phase 11 country
- Insomnia in Patients Undergoing Chemotherapy and Radiation Therapy for Head and Neck CancerWithdrawnNCT006165901 country
- Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung CancerCompletedNCT00101348Phase 1/21 country
- Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck CancerCompletedNCT00492089Phase 21 country
- Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 31 country
- 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)CompletedNCT00031681Phase 11 country
- Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid TumorsCompletedNCT00014456Phase 11 country
- External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain MetastasesStatus unknownNCT00637637Phase 21 country
- Chemotherapy in Treating Patients With Solid TumorsCompletedNCT00003103Phase 1/21 country