Eosinophilia clinical trials
The registry lists 52 studies for Eosinophilia across more than 10 countries. 9 are recruiting or about to start. 12 of them are mainly about Eosinophilia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29. Counting its 3 narrower conditions too, such as Eosinophilic Esophagitis: 316 studies, 67 open.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (8) · Ellodi Pharmaceuticals, LP (4) · GlaxoSmithKline (3) · Children's Hospital Medical Center, Cincinnati (3) · Novartis Pharmaceuticals (2) · Celgene (2) · Stanford University (2) · Second Affiliated Hospital, School of Medicine, Zhejiang University (2)
What is being tested here
Drugs under test in Eosinophilia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ketotifen | 1 | 1 | 1 |
| Baricitinib | 1 | 0 | 1 |
| Mepolizumab | 0 | 4 | 6 |
| APT-1011 | 0 | 3 | 3 |
| Benralizumab | 0 | 2 | 3 |
| Cendakimab | 0 | 2 | 2 |
| Dexpramipexole | 0 | 0 | 2 |
| Fevipiprant | 0 | 0 | 2 |
| Ruxolitinib | 0 | 0 | 1 |
| Dupilumab | 0 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Apr 2027Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia · Phase 3 · Craig A. Friesen, MD
- Dec 2026Association Between Disease Severity and Clinical, Histopathological, and Eosinophilic Markers in Patients With Bullous Pemphigoid (BP-EPIC) · Istanbul Training and Research Hospital
- Dec 2026Efficacy and Safety of Stapokibart in Non-Allergic Rhinitis With Eosinophilia Syndrome · Huazhong University of Science and Technology
Who these studies take
Of the 8 Eosinophilia studies recruiting now, 3 (38%) set no upper age limit and 3 (38%) stop at 75 or younger. 5 (63%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (63%) | 5 (63%) |
| 18 | 7 (88%) | 7 (88%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 6 (75%) | 6 (75%) |
| 75 | 5 (63%) | 5 (63%) |
| 85 | 5 (63%) | 5 (63%) |
Across all 52 studies, recruiting or not: 38% stop at 75 or younger and 23% at 65; 44% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 52. Browse all 52 → or search them.
- A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease ProgressionRecruitingNCT000918711 country
- Activation and Function of Eosinophils in Conditions With Blood or Tissue EosinophiliaRecruitingNCT000014061 country
- Study of Gastric Motility in Eosinophilic GastritisRecruitingNCT052294321 country
- Natural History of Hypereosinophilia and Hypereosinophilic SyndromesRecruitingNCT040181181 country
- Ketotifen for Children With Functional Dyspepsia in Association With Duodenal EosinophiliaRecruitingNCT02484248Phase 31 country
- Efficacy and Safety of Stapokibart in Non-Allergic Rhinitis With Eosinophilia SyndromeNot yet recruitingNCT07240376Not applicable1 country
- Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic DisordersRecruitingNCT002675011 country
- Specific Versus Empirical Anthelminthic Treatment in EosinophiliaRecruitingNCT06265870Not applicable1 country
- Baricitinib Plus Glucocorticoid for Eosinophilia in IgG4-RDRecruitingNCT05781516Not applicable1 country
- Home Air Purification for Eosinophilic COPDCompletedNCT04252235Not applicable1 country
- Natural History of Severe Allergic Inflammation and ReactionsCompletedNCT011642411 country
- Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic DisordersActive, not recruitingNCT03801434Phase 21 country
- Dupilumab in Type 2-Inflamed COPD Across the Full Spectrum of Airflow Limitation: An Italian Multicentre Retrospective Cohort StudyCompletedNCT077880921 country
- New Cases of EoE in Children in Poland.CompletedNCT077723881 country
- Association Between Disease Severity and Clinical, Histopathological, and Eosinophilic Markers in Patients With Bullous Pemphigoid (BP-EPIC)Active, not recruitingNCT076494861 country
- Mepolizumab for COPD Hospital Eosinophilic Admissions Pragmatic TrialCompletedNCT04075331Phase 2/31 country
- Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic EsophagitisCompletedNCT04991935Phase 315 countries
- A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)CompletedNCT03011372Phase 211 countries
- Expanded Access Protocol for Patients With Eosinophilic EsophagitisNo longer availableNCT050951161 country
- 24-Week Induction Study of APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE 3)CompletedNCT05634746Phase 32 countries
- A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal PolypsActive, not recruitingNCT05942222Phase 41 country
- A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic EsophagitisCompletedNCT04753697Phase 315 countries
- A Study to Investigate the Use of Benralizumab in Patients With Bullous Pemphigoid.TerminatedNCT04612790Phase 311 countries
- Gastrointestinal STRING Test With Oral ImmunotherapyTerminatedNCT04943744Early Phase 11 country
- Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)Active, not recruitingNCT04149470Phase 41 country
- Mepolizumab in Episodic Angioedema With EosinophiliaTerminatedNCT04128371Phase 21 country
- Efficacy and Safety APT-1011 in Adolescent Subjects With Eosinophilic Esophagitis (EoE) - A Sub-Study of the FLUTE-2 TrialCompletedNCT05083312Phase 32 countries
- Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)CompletedNCT04281108Phase 33 countries
- Treatment of Asymptomatic Toxocariasis With Albendazole in ChildrenActive, not recruitingNCT00755560Phase 31 country
- Relationship Between Cardiovascular Disease in Asthma and Eosinophil Subtypes and Biomarkers of Bronchial Remodeling.Status unknownNCT05589779
- Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and Eosinophilia Among Primary Care PatientsCompletedNCT030188081 country
- Steroid Treatment for Hypereosinophilic SyndromeCompletedNCT01524536Phase 41 country
- Study to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic SyndromeStatus unknownNCT02130882Phase 2/31 country
- A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With EosinophiliaTerminatedNCT03810183Phase 22 countries
- Drivers of Eosinophilic COPD ExacerbationsStatus unknownNCT049610601 country
- Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and EosinophiliaCompletedNCT02217332Phase 21 country
- Phase II Gleevec Idiopathic Hypereosinophilic SyndromeTerminatedNCT00230334Phase 21 country
- Effect of OC459 on the Response to Rhinovirus Challenge in AsthmaCompletedNCT02660489Phase 21 country
- Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic PolyposisCompletedNCT03450083Phase 21 country
- Research for Angiostrongylus Cantonensis and Costaricensis in French West Indies and French GuianaStatus unknownNCT033788821 country
- Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant AsthmaCompletedNCT032372211 country
- Registry for Eosinophilic Gastrointestinal Disorders (REGID)CompletedNCT013825631 country
- Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.WithdrawnNCT03989635Phase 2
- Clinical Characteristics and Treatment of Chest Tightness Variant AsthmaStatus unknownNCT04322422Not applicable1 country
- Intravenous Mepolizumab In Subjects With Hypereosinophilic Syndromes (HES)CompletedNCT00086658Phase 38 countries
- Identifying Serum Cytokine Profiles of Distinct Inflammatory Phenotypes in Severe AsthmaCompletedNCT035635211 country
- Functional Dyspepsia (FD) - Clinical Response to Montelukast in ChildrenCompletedNCT023606961 country
- Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic SyndromeStatus unknownNCT02101138Phase 21 country
- Open-Label Extension Of Intravenous Mepolizumab In Patients With Hypereosinophilic SyndromeTerminatedNCT00097370Phase 37 countries
- Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity IndexStatus unknownNCT009392634 countries