Diffuse Intrinsic Pontine Glioma: all 122 studies
Page 1 of 2. Open to participants first (40), then studies with results posted, then the rest; newest registration first within each.
- IMPT Versus IMRT for Diffuse Intrinsic Pontine GliomaNot yet recruitingNCT07869524Phase 3
- Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of ResponseNot yet recruitingNCT07767110Phase 1/2
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).RecruitingNCT07680439Phase 2
- NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain TumorsRecruitingNCT07664176Phase 1
- Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPGNot yet recruitingNCT07644312Phase 2
- A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine GliomaRecruitingNCT07589257Phase 2
- H3K27M-specific Immune Effector Cells Targeting DMG/DIPGNot yet recruitingNCT07501156Phase 1/2
- Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid TumorNot yet recruitingNCT07331064Phase 1
- Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)Not yet recruitingNCT07206849Phase 2
- Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationRecruitingNCT07076498Phase 1
- IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)Not yet recruitingNCT06946680Phase 1
- ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade GliomasRecruitingNCT06838676Phase 2
- Atovaquone Combined With Radiation in Children With Malignant Brain TumorsRecruitingNCT06624371Phase 1
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasRecruitingNCT06465199Phase 1/2
- Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant GliomaNot yet recruitingNCT06396481Early Phase 1
- Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK FusionRecruitingNCT06333899Early Phase 1
- Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPGRecruitingNCT06221553Phase 1
- Study of Olutasidenib and Temozolomide in HGGRecruitingNCT06161974Phase 2
- xPedite: A Study to Expedite DIPG and DMG ResearchRecruitingNCT06140719
- RE-irradiation of Diffuse MIdline Glioma paTientsNot yet recruitingNCT06093165Not applicable
- Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of AgeRecruitingNCT05956821Phase 1/2
- Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantRecruitingNCT05843253Phase 2
- Targeted Pediatric High-Grade Glioma TherapyRecruitingNCT05839379
- FUS Etoposide for DMGRecruitingNCT05762419Phase 1
- Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine GliomaRecruitingNCT05717712Phase 1
- Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine GliomaRecruitingNCT05717699Phase 1
- Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0RecruitingNCT05476939Phase 3
- GD2-CAR T Cells for Pediatric Brain TumoursRecruitingNCT05298995Phase 1
- Lutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsRecruitingNCT05278208Phase 1/2
- PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent MedulloblastomaRecruitingNCT05096481Phase 2
- Combination Therapy for the Treatment of Diffuse Midline GliomasRecruitingNCT05009992Phase 2
- rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMGRecruitingNCT04943848Phase 1
- CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and LymphomaRecruitingNCT04870944Phase 1/2
- A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK FusionRecruitingNCT04655404Early Phase 1
- A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine GliomaRecruitingNCT04250064Phase 2
- Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 1
- C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)RecruitingNCT04099797Phase 1
- Immune Modulatory DC Vaccine Against Brain TumorNot yet recruitingNCT03914768Phase 1
- International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and RepositoryRecruitingNCT03101813
- Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem GliomaRecruitingNCT01106794
- Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)TerminatedNCT04804709Phase 1Results posted
- A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
- Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid TumorsCompletedNCT03709680Phase 2Results posted
- REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent GliomaTerminatedNCT03690869Phase 1/2Results posted
- Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS TumorsActive, not recruitingNCT03598244Phase 1Results posted
- MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT03566199Phase 1/2Results posted
- Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their CaregiversCompletedNCT03538587Not applicableResults posted
- Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain TumorsCompletedNCT03387020Phase 1Results posted
- A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPGTerminatedNCT03330197Phase 1/2Results posted
- H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other GliomasCompletedNCT02960230Phase 1/2Results posted
- Trial of Panobinostat in Children With Diffuse Intrinsic Pontine GliomaCompletedNCT02717455Phase 1Results posted
- A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation TherapyTerminatedNCT02607124Phase 1/2Results posted
- Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine GliomasCompletedNCT01922076Phase 1Results posted
- Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22TerminatedNCT01884740Phase 1/2Results posted
- Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT01189266Phase 1/2Results posted
- Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)TerminatedNCT01182350Phase 2Results posted
- Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine GliomaCompletedNCT00879437Phase 2Results posted
- A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine GliomasCompletedNCT00036569Phase 2Results posted
- PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and EpendymomaSuspendedNCT06639607Phase 1/2
- A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With CancerActive, not recruitingNCT06521567Phase 1/2
- Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline GliomaNo longer availableNCT06439849
- Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System TumorsActive, not recruitingNCT05768880Phase 1
- Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-alteredNo longer availableNCT05518838
- Oral AMXT 1501 Dicaprate in Combination With IV DFMOTerminatedNCT05500508Phase 1/2
- Expanded Access Use of ONC201 in a Patient With Diffuse Intrinsic Pontine GliomasNo longer availableNCT05392374
- A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPGSuspendedNCT05123534Phase 2
- 131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine GliomaWithdrawnNCT05063357Phase 1
- A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT04978727Phase 1
- Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine GliomaCompletedNCT04911621Phase 1/2
- PEACH TRIAL- Precision Medicine and Adoptive Cellular TherapyActive, not recruitingNCT04837547Phase 1
- A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)TerminatedNCT04771897Phase 1
- Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in MonotherapyActive, not recruitingNCT04758533Phase 1/2
- Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine GliomaCompletedNCT04749641Phase 1
- HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their CaregiversCompletedNCT04670016
- Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in ChildrenStatus unknownNCT04532229Phase 3
- Phase I Study of Marizomib + Panobinostat for Children With DIPGTerminatedNCT04341311Phase 1
- CED of MTX110 Newly Diagnosed Diffuse Midline GliomasCompletedNCT04264143Phase 1
- 9-ING-41 in Pediatric Patients With Refractory Malignancies.TerminatedNCT04239092Phase 1
- Gemcitabine in Newly-Diagnosed Diffuse Midline GliomaWithdrawnNCT04051047Early Phase 1
- Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGActive, not recruitingNCT04049669Phase 2
- Fimepinostat in Treating Brain Tumors in Children and Young AdultsActive, not recruitingNCT03893487Early Phase 1
- Hypofractionated Radiotherapy for Recurrent DIPGCompletedNCT03841435Not applicable
- Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline GliomasCompletedNCT03696355Phase 1
- A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With GliomasWithdrawnNCT03632317Phase 2
- Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt CoursesActive, not recruitingNCT03620032Phase 2
- A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade GliomaActive, not recruitingNCT03605550Phase 1
- Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and SarcomasActive, not recruitingNCT03478462Phase 1
- ONC201 in Pediatric H3 K27M GliomasTerminatedNCT03416530Phase 1
- Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)TerminatedNCT03396575Phase 1
- A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)CompletedNCT03355794Phase 1
- International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)Status unknownNCT03243461Phase 3
- Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine GliomasCompletedNCT03178032Phase 1
- Re-Irradiation of Progressive or Recurrent DIPGCompletedNCT03126266Not applicable
- CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)CompletedNCT03086616Phase 1
- Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPGActive, not recruitingNCT03033992Not applicable
- Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT02992015Early Phase 1
- Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor LinesStatus unknownNCT02840123Phase 1
- Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine GliomaTerminatedNCT02758366Phase 2
- A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade GliomasCompletedNCT02750891Phase 1/2
- A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG)SuspendedNCT02742883Phase 2