Dermatofibrosarcoma clinical trials
The registry lists 41 studies for Dermatofibrosarcoma across more than 10 countries. 9 are recruiting or about to start. 9 of them are mainly about Dermatofibrosarcoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Cancer Institute (NCI) (8) · Memorial Sloan Kettering Cancer Center (3) · Children's Oncology Group (2) · Brown University (2) · Oslo University Hospital (2) · Novartis Pharmaceuticals (2) · City of Hope Medical Center (1) · St. Jude Children's Research Hospital (1)
What is being tested here
Drugs under test in Dermatofibrosarcoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Doxorubicin | 1 | 3 | 5 |
| Pazopanib | 1 | 1 | 4 |
| Toripalimab | 1 | 0 | 1 |
| Anlotinib | 1 | 0 | 1 |
| Liposomal doxorubicin | 1 | 0 | 1 |
| Peposertib | 1 | 0 | 1 |
| Selinexor | 1 | 0 | 1 |
| Pembrolizumab | 1 | 0 | 1 |
| Imatinib | 0 | 0 | 5 |
| Ifosfamide | 0 | 3 | 3 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Immune checkpoint inhibitors 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Jan 2027Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma · Jonsson Comprehensive Cancer Center
- Apr 2027A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg · Memorial Sloan Kettering Cancer Center
- May 2027Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma · National Cancer Institute (NCI)
Who these studies take
Of the 6 Dermatofibrosarcoma studies recruiting now, 5 (83%) set no upper age limit and 1 (17%) stop at 75 or younger. 2 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (17%) | 1 (17%) |
| 18 | 6 (100%) | 6 (100%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 5 (83%) | 5 (83%) |
| 50 | 5 (83%) | 5 (83%) |
| 65 | 5 (83%) | 5 (83%) |
| 75 | 5 (83%) | 5 (83%) |
| 85 | 5 (83%) | 5 (83%) |
Across all 41 studies, recruiting or not: 17% stop at 75 or younger and 15% at 65; 44% take children; 2% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 41 of 41. search them.
- Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced SarcomaRecruitingNCT05711615Phase 11 country
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)RecruitingNCT06239272Phase 1/21 country
- Exploratory Study on Toripalimab and Anlotinib Combined With Standard Chemotherapy for Refractory Dermatofibrosarcoma ProtuberansNot yet recruitingNCT07646080Phase 2
- A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid TumorsRecruitingNCT06789172Phase 13 countries
- A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or LegRecruitingNCT04332874Phase 21 country
- Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue SarcomaRecruitingNCT07169344Phase 21 country
- Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.RecruitingNCT07173972Phase 21 country
- NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG TechniqueNot yet recruitingNCT06610071Phase 1
- Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue SarcomaNot yet recruitingNCT06526897Not applicable
- Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib MesylateCompletedNCT01046487Phase 11 country
- Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryCompletedNCT02180867Phase 2/33 countries
- Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue SarcomaActive, not recruitingNCT04420975Phase 11 country
- CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With SarcomaCompletedNCT03425279Phase 1/23 countries
- Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic SarcomasCompletedNCT04242238Phase 11 country
- A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With LeiomyosarcomaTerminatedNCT04996004Phase 21 country
- Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue SarcomaWithdrawnNCT06370871Phase 3
- ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or MyxofibrosarcomaActive, not recruitingNCT04480502Phase 22 countries
- Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue SarcomaCompletedNCT02584309Phase 21 country
- Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by SurgeryCompletedNCT03009201Phase 11 country
- Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic SarcomaTerminatedNCT02601209Phase 1/21 country
- Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 35 countries
- Phase 2 Study of 9-ING-41 With Chemotherapy in SarcomaWithdrawnNCT05116800Phase 21 country
- A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced SarcomasWithdrawnNCT04906876Phase 21 country
- Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk WallStatus unknownNCT03651375Phase 21 country
- Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and YoungerCompletedNCT03381846Not applicable1 country
- Spanish Registry of Mohs SurgeryCompletedNCT023105031 country
- Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid TumorsCompletedNCT01962103Phase 1/27 countries
- Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1/21 country
- AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue SarcomaCompletedNCT00659360Phase 22 countries
- Alisertib in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01653028Phase 21 country
- Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase EnzymesCompletedNCT00171912Phase 21 country
- Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare DiseasesCompletedNCT00154388Phase 2
- Phase II Pazopanib Study in Advanced DermatofibrosarcomasTerminatedNCT01059656Phase 21 country
- Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue SarcomaCompletedNCT00720174Phase 11 country
- Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent SarcomasCompletedNCT00474994Phase 21 country
- Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue SarcomaTerminatedNCT00740597Phase 21 country
- Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue SarcomaStatus unknownNCT00334854Phase 39 countries
- Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for SarcomaWithdrawnNCT00334984Not applicable
- Imatinib Mesylate in Treating Patients With Locally Recurrent or Metastatic Dermatofibrosarcoma ProtuberansCompletedNCT00084630Phase 21 country
- Neoadjuvant Imatinib in Dermatofibrosarcoma ProtuberansCompletedNCT00243191Phase 21 country
- Imatinib in Dermatofibrosarcoma Protuberans (DFSP)CompletedNCT00122473Phase 1/21 country