Depressive Disorder, Treatment-Resistant: all 472 studies
Page 1 of 5. Open to participants first (151), then studies with results posted, then the rest; newest registration first within each.
- Effect of Neurofeedback and TMSNot yet recruitingNCT07892287Not applicable
- Sensation Seeking and TMS Response in TRDRecruitingNCT07889739
- French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy ControlsRecruitingNCT07881016Not applicable
- SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant DepressionRecruitingNCT07876908Not applicable
- EEG-Guided Transcranial Magnetic Stimulation for Adults With DepressionNot yet recruitingNCT07862205Not applicable
- Dehydroepiandrosterone (DHEA) as Augmentation of Standard Antidepressants in Treatment-resistant Depression.RecruitingNCT07843927Phase 3
- Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant DepressionNot yet recruitingNCT07834762Not applicable
- Ketamine Treatment for Treatment-Resistant Depression - the Role of FramingNot yet recruitingNCT07824973Not applicable
- The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.Not yet recruitingNCT07810738Phase 2
- Behavioural Activation Therapy and Ketamine for Treatment-Resistant DepressionNot yet recruitingNCT07801703Phase 2/3
- Maintenance Individualized Neuromodulation and Depression-detection Via Sensors for Early TreatmentNot yet recruitingNCT07779330Not applicable
- Study of rTMS in Maintenance in Treatment Resistant DepressionNot yet recruitingNCT07760168Phase 3
- One-Day cTBS Over the PrecuneusRecruitingNCT07758010Not applicable
- EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorder Receiving ECTRecruitingNCT07748091
- Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to TreatmentRecruitingNCT07741981Not applicable
- EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECTRecruitingNCT07740694
- Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant DepressionEnrolling by invitationNCT07737990Not applicable
- A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant DepressionRecruitingNCT07716098Phase 3
- Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD ClientsRecruitingNCT07706478
- Cannabidiol Oil for Treatment-Resistant Major DepressionRecruitingNCT07696871Phase 1/2
- Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium - MaintenanceNot yet recruitingNCT07684794Not applicable
- Biomarker-Guided Antidepressant SelectionRecruitingNCT07680140Phase 4
- Relationship of Peripheral Inflammatory and Neuroprotective Biomarkers With Response to Intermittent Theta Burst Stimulation in Treatment-Resistant DepressionRecruitingNCT07673913Not applicable
- Lumateperone for Late-Life DepressionRecruitingNCT07623135Phase 3
- Accelerated iTBS for Major DepressionRecruitingNCT07603804Not applicable
- Regulated Stimulation for Optimized Network Activity and Therapeutic EquilibriumRecruitingNCT07594483Not applicable
- Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)RecruitingNCT07569198Phase 2
- Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant DepressionRecruitingNCT07563868Not applicable
- ALTO-207 in Adults With Treatment-resistant Depression (TRD)RecruitingNCT07553637Phase 2
- Transcranial Photobiomodulation (tPBM) for Somatic Symptoms in Treatment-Resistant DepressionRecruitingNCT07543328Not applicable
- Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant DepressionNot yet recruitingNCT07528157Not applicable
- ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1RecruitingNCT07528014
- Mindfulness Engaged Neurostimulation for Depression (MEND II)RecruitingNCT07512284Phase 2
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use DisorderNot yet recruitingNCT07499583Phase 1/2
- ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive DisorderRecruitingNCT07474974Not applicable
- Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant DepressionRecruitingNCT07422519Not applicable
- Mitochondrial Function After KetamineNot yet recruitingNCT07399756
- Ketogenic Diet and Neuromodulation in Treatment Resistant DepressionNot yet recruitingNCT07376018Not applicable
- Understanding Music and Mindfulness Preferences in Psilocybin-Assisted PsychotherapyNot yet recruitingNCT07373535Phase 2
- Esketamine With or Without Integration Therapy for Treatment-Resistant DepressionRecruitingNCT07369102Phase 4
- Neuronavigated aiTBS for TRDNot yet recruitingNCT07329153Not applicable
- Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant DepressionRecruitingNCT07324070Not applicable
- Vagus Nerve Stimulation (VNS) Electroencephalogram (EEG) Protocol SupplementNot yet recruitingNCT07310381Not applicable
- Parcel-guided rTMS for Major Depressive DisorderNot yet recruitingNCT07287839Phase 2
- ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant ResponseRecruitingNCT07284667Phase 2
- Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst Stimulation in Patients With Treatment-Resistant DepressionRecruitingNCT07264452Not applicable
- Sustained Mood Improvement With Laughing Gas ExposureNot yet recruitingNCT07262008Phase 3
- Ketamine-Assisted Psychotherapy for Treatment-Resistant DepressionNot yet recruitingNCT07247006Phase 2
- A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS TrialRecruitingNCT07227103Phase 2/3
- Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety StudyRecruitingNCT07217223Not applicable
- Accelerated Neuromodulation of Anterior Cingulate Cortex for DepressionRecruitingNCT07212465Not applicable
- Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant DepressionRecruitingNCT07211438Phase 2
- Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)RecruitingNCT07210112Phase 2
- Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods.Enrolling by invitationNCT07207239Not applicable
- Mental Health Mission Mood Disorder Cohort StudyNot yet recruitingNCT07189689
- Randomized Controlled Trial Testing the Efficacy of Transcranial Magnetic Stimulation by Accelerated & High-dose Theta-burst, Functional Imaging Guided, in the Treatment of Depression in Elderly Subjects With Cognitive ImpairmentNot yet recruitingNCT07188753Not applicable
- Psilocybin Microdosing With Psychotherapy for Treatment-Resistant DepressionRecruitingNCT07183748Phase 2
- Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant DepressionRecruitingNCT07166289Not applicable
- Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant DepressionRecruitingNCT07146503
- Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar DepressionRecruitingNCT07108257Not applicable
- Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant DepressionRecruitingNCT07094789Not applicable
- Ketamine Augmentation of ECT in Treatment-Resistant DepressionRecruitingNCT07088380Phase 3
- Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant DepressionRecruitingNCT07080723Phase 4
- Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan TrialNot yet recruitingNCT07043738Not applicable
- Maintenance rTMS for Depression (Maitr-De)RecruitingNCT06938841Not applicable
- COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant DepressionRecruitingNCT06895863Not applicable
- Comparison of Different Acceleration Modes of Transcranial Magnetic StimulationNot yet recruitingNCT06881030Not applicable
- Accelerated vs. Conventional Theta Burst Stimulation for Late-life DepressionRecruitingNCT06854367Not applicable
- TACS on High-inflammatory and Refractory DepressionRecruitingNCT06812923Not applicable
- Personalized DBS Targeting for Treating DepressionRecruitingNCT06784388Early Phase 1
- InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpressionRecruitingNCT06781697Phase 3
- Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat DepressionRecruitingNCT06773949Not applicable
- Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot StudyRecruitingNCT06732089
- Intravenous Ketamine for Treatment-Resistant DepressionRecruitingNCT06668571Phase 2
- Efficacy of Deep Brain Stimulation(DBS) for Treatment-Resistant Depression(TRD)Not yet recruitingNCT06542900Not applicable
- Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain StimulationRecruitingNCT06542094Not applicable
- A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)RecruitingNCT06524830Phase 2
- Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)RecruitingNCT06518720Phase 2
- Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)RecruitingNCT06512220Phase 2
- Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionRecruitingNCT06511908Phase 2
- rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant DepressionRecruitingNCT06511544Not applicable
- IV Ketamine Vs. in Esketamine for MDD TRDRecruitingNCT06488586
- Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant DepressionRecruitingNCT06480201Phase 1
- Natural History of Depression, Bipolar Disorder and Suicide RiskRecruitingNCT06462196
- Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)RecruitingNCT06423430Not applicable
- Physical Activity Program for TRDRecruitingNCT06404320Not applicable
- Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant DepressionNot yet recruitingNCT06391723Not applicable
- Psilocybin for Hospitalized Patients with Treatment-resistant DepressionRecruitingNCT06378229Phase 2
- pBFS-guided rTMS Over DMPFC for Treatment-Resistant DepressionRecruitingNCT06350396Not applicable
- Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple SclerosisRecruitingNCT06329414
- Accelerated Bilateral Sequential Theta Burst Stimulation in Older Adults With Treatment-resistant DepressionRecruitingNCT06323486Not applicable
- Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant DepressionRecruitingNCT06278779Phase 4
- pBFS Guided rTMS Over Different Targets for Treatment-Resistant DepressionNot yet recruitingNCT06255561Not applicable
- Transcranial Alternating Current Stimulation for Treatment-Resistant DepressionNot yet recruitingNCT06172413Not applicable
- The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant DepressionRecruitingNCT06163625Not applicable
- Psilocybin rTMS for Treatment Resistant DepressionRecruitingNCT06132178Phase 2
- Chronic Anergic-anhedonic Depression Open TrialRecruitingNCT06110507
- Studying Patterns in Patient Engagement Among Treatment Resistant Depression PatientsNot yet recruitingNCT06101914
- DBS for DepressionRecruitingNCT06096207Phase 1
- rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFSRecruitingNCT06095778Not applicable