Depressive Disorder, Major: all 2,805 studies
Page 14 of 29. Open to participants first (565), then studies with results posted, then the rest; newest registration first within each.
- Vulnerability Markers for DepressionCompletedNCT06402422
- Mindfulness Engaged Neurostimulation for DepressionActive, not recruitingNCT06399406Phase 2
- Peer-led Intervention for Individuals With Major Depression.CompletedNCT06398561Not applicable
- PD, PK, and Safety of ALTO-203 in Patients With MDDCompletedNCT06391593Phase 2
- Lifestyle MIND- Feasibility of Wait-list ControlWithdrawnNCT06384521Not applicable
- Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD PatientsCompletedNCT06372834Not applicable
- Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using SolriamfetolCompletedNCT06360419Phase 3
- New Investigational Stimulation Protocol for Treatment of Major Depression Disorder (MDD)CompletedNCT06357832Not applicable
- Brain Oscillation-synchronized Stimulation of the Frontal Cortex in Major Depressive DisorderStatus unknownNCT06345651Not applicable
- Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of PsilocybinActive, not recruitingNCT06341426Phase 2
- Getting Out of the House: Using Behavioral Activation to Increase Community ParticipationActive, not recruitingNCT06336616Not applicable
- Standardized Assessment in Depression Treatment in Routine Psychiatric ServicesCompletedNCT06332261
- Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent DepressionCompletedNCT06331572
- Sleep Quality, Cognitive Performance, and Computerized Cognitive TrainingWithdrawnNCT06328140
- Behavioral Activation for Depression and Habitual RuminationActive, not recruitingNCT06322420Not applicable
- Altering Default Mode Network Activity With Transcranial Focused Ultrasound to Reduce Depressive SymptomsActive, not recruitingNCT06320028Phase 1/2
- Trial of Mirtazapine for Depression in IBDCompletedNCT06309472Phase 2
- Psilocybin for Major Depressive Disorder (MDD)Active, not recruitingNCT06308653Phase 3
- Testing a Transdiagnostic TMS Treatment TargetCompletedNCT06282146Early Phase 1
- Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Venlafaxine Hydrochloride Sustained-release Tablets in Patients With Major Depression DisorderCompletedNCT06278038Not applicable
- A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive DisorderCompletedNCT06267846Phase 2
- Individualized (fMRI-guided) TMS Treatment for DepressionCompletedNCT06266390Not applicable
- Take-home Functional Electrical Stimulation for MDDActive, not recruitingNCT06261177Not applicable
- A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive DisorderCompletedNCT06254612Phase 2
- Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative ThinkingCompletedNCT06254144
- Diet and DepressionCompletedNCT06252701Not applicable
- Effects of Electroacupuncture on Cognitive Symptoms in Major Depressive DisorderCompletedNCT06239740Not applicable
- A Phase 2a Study to Evaluate the Safety and Tolerability of GM-2505 in Patients With MDDCompletedNCT06236880Phase 2
- Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant DepressionCompletedNCT06232291
- Psilocybin for Treatment-Resistant DepressionCompletedNCT06230757Phase 2
- Inter-Brain Synchrony in Psychotherapy for DepressionCompletedNCT06196346Not applicable
- Optimizing tDCS Protocol for Clinical Use in Major Depressive DisorderCompletedNCT06165445Not applicable
- Behavioral and Neuronal Correlates of Human Mood StatesCompletedNCT06159595Not applicable
- EMA-Guided Maintenance TMS for DepressionActive, not recruitingNCT06145594Not applicable
- RTMS Feasibility Study on Adolescent Depression StimulationCompletedNCT06126198Not applicable
- The Biological Specificity of Acupoints Between Major Depressive Disorder Patients and Healthy ControlsCompletedNCT06114342
- Practical Application of Accelerated iTBS for MDDCompletedNCT06113575Not applicable
- Neuromodulation of Different Doses to Treat TRD Guided by pBFS TechniqueSuspendedNCT06112652Not applicable
- Transcranial Magnetic Stimulation in Patients With Depression and Non-suicidal Self-injuryStatus unknownNCT06110585Not applicable
- Reward Processing and Depressive Subtypes: Identifying Neural BiotypesCompletedNCT06080646
- Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive DisorderCompletedNCT06058039Phase 3
- Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive DisorderCompletedNCT06058013Phase 3
- Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) NeurofeedbackCompletedNCT06050070Not applicable
- Validation of Accexible as a Tool for Screening and Monitoring Depression.CompletedNCT06044818
- Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation TherapyActive, not recruitingNCT06043401
- The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health ProblemsCompletedNCT06035159Not applicable
- Study to Assess the Safety and Effectiveness of NMRA-335140-501TerminatedNCT06029439Phase 3
- Study to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive DisorderCompletedNCT06029426Phase 3
- Self-guided Treatment for DepressionActive, not recruitingNCT06028984Not applicable
- Positive Feedback vs. No-Feedback Games for Behavioral ChangeCompletedNCT06025838Not applicable
- Low-Intensity Focused Ultrasound for Treatment-Resistant DepressionSuspendedNCT06013384Not applicable
- Brain Network Dynamics of Depression During Esketamine TreatmentCompletedNCT06012916
- Individual Patient Esmethadone (REL-1017) Expanded Access ProgramNo longer availableNCT06009003
- Rise Study for DepressionCompletedNCT06003361Not applicable
- Frequency and E-field Enhancement of ITBS for Depression (FREED)CompletedNCT06003309Not applicable
- Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population.Active, not recruitingNCT05989412Not applicable
- Efficacy of Mirtazapine in Major Depressive Disorder With InsomniaCompletedNCT05978219Phase 4
- Imagery Rescripting as Treatment for DepressionActive, not recruitingNCT05976945Not applicable
- Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With DepressionActive, not recruitingNCT05966532
- Study to Assess Accuracy of Rapid Mood Screener in Adult Participants With Unipolar Major Depressive Disorder or Bipolar 1 Disorder in Real World SettingCompletedNCT05956483
- Comparative Responses to 15 Different Antidepressants in Major Depressive DisorderCompletedNCT05952713
- Ketamine-Assisted Mindfulness-Based Cognitive Therapy for Depression: A Pilot StudyActive, not recruitingNCT05950711Phase 4
- Sertraline Versus Escitalopram in South Asian Participants With Moderate to Severe Major Depressive DisorderCompletedNCT05950061Phase 3
- Relationship Between Major Depression and Periodontal DiseasesStatus unknownNCT05950009
- Two Doses of Psilocybin for the Treatment of MDD in Adults With CancerActive, not recruitingNCT05947383Phase 2
- Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in DepressionSuspendedNCT05933148Not applicable
- Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment ResponseCompletedNCT05930509Not applicable
- First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM)WithdrawnNCT05921929Phase 1
- Multi-Omic, Clinomic and Digitomic Attributes of Major Depression for Integrative AnalyticsActive, not recruitingNCT05910957
- Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)CompletedNCT05905120Phase 1
- Trans Care: An Online Intervention to Reduce Symptoms of Gender DysphoriaCompletedNCT05903911Not applicable
- Repetitive Versus Deep Transcranial Magnetic Stimulation for Major DepressionActive, not recruitingNCT05902312Not applicable
- Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Sleep DeprivationCompletedNCT05893173
- Trans Care: An Online Intervention to Reduce Symptoms of Gender DysphoriaCompletedNCT05884307Not applicable
- Synaptic Imaging and Network Activity in Treatment Resistant DepressionCompletedNCT05870501Not applicable
- Boosting Psychotherapy Effects by Means of Transcranial Direct Current StimulationCompletedNCT05866042Not applicable
- Deep rTMS for Depression in Older AdultsCompletedNCT05855850Not applicable
- A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)CompletedNCT05841030
- Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective DisordersStatus unknownNCT05840861
- The CARE (Collaborative Adolescent Running Experience) ProjectCompletedNCT05837351Not applicable
- Open Label Optimization StudyActive, not recruitingNCT05819021
- Mobile Observation Of DepressionCompletedNCT05815459
- RESILIENT : A Self-Managed Online Platform for Victims of Sexual AssaultActive, not recruitingNCT05811897Not applicable
- Glutamate Emotion Memory StudyStatus unknownNCT05809609Not applicable
- Cognition in Mindfulness: Negativity and DepressionTerminatedNCT05802966
- A Trial of GH001 in Patients With Treatment-resistant DepressionCompletedNCT05800860Phase 2
- Potential Predictive Biological Markers of Major Depression Response to Citalopram Therapy in Anorexia Nervosa.Status unknownNCT05795283
- Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive DisordersCompletedNCT05792540Phase 2
- TaKeTiNa in the Treatment of Depression: a Pilot Study.Status unknownNCT05778643Not applicable
- Specialized Pro-resolving Lipid Mediators and Treatment Resistant DepressionActive, not recruitingNCT05774665Phase 2
- The Role of Social Determinants in Cardiovascular Health and Vascular FunctionCompletedNCT05772221Not applicable
- Clinical Validation of Samsung SmartwatchActive, not recruitingNCT05767593
- The Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With DepressionStatus unknownNCT05762458Phase 2
- Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD)CompletedNCT05757791Phase 2
- A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive DisorderActive, not recruitingNCT05733546Phase 2
- D-Cycloserine+iTBS PK StudyCompletedNCT05731323Phase 1
- Technology-Assisted Implementation of a Mobile Health Program for Serious Mental IllnessCompletedNCT05725785Not applicable
- Alexithymia Intervention for SuicideTerminatedNCT05724953Phase 1
- The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive DisorderCompletedNCT05720637Not applicable
- Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSDCompletedNCT05717439