Death, Sudden, Cardiac clinical trials
The registry lists 363 studies for Death, Sudden, Cardiac across more than 10 countries. 84 are recruiting or about to start. 149 of them are mainly about Death, Sudden, Cardiac (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (14) · Abbott Medical Devices (8) · University College, London (8) · Zoll Medical Corporation (7) · Johns Hopkins University (6) · Boston Scientific Corporation (6) · Medtronic Cardiac Rhythm and Heart Failure (6) · Technical University of Munich (4)
What is being tested here
Drugs under test in Death, Sudden, Cardiac studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Epinephrine | 1 | 0 | 1 |
| Tideglusib | 1 | 0 | 1 |
| Carvedilol | 1 | 0 | 1 |
| Eleclazine | 0 | 1 | 2 |
| Omega-3 fatty acid | 0 | 1 | 2 |
| Amiodarone | 0 | 1 | 2 |
| Mycophenolic Acid | 0 | 1 | 1 |
| Lumacaftor | 0 | 0 | 1 |
| Ivacaftor | 0 | 0 | 1 |
| Regadenoson | 0 | 0 | 1 |
Drug classes tested here Beta blockers 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026PRE-DETERMINE Cohort Study · Brigham and Women's Hospital
- Dec 2026Gene Therapy for ACM Due to a PKP2 Pathogenic Variant · Lexeo Therapeutics
- Dec 2026IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry · University of California, Los Angeles
- Dec 2026AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM) · Idoven 1903 S.L.
- Dec 2026PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) · Singapore General Hospital
- Dec 2026Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors · Northwell Health
- Dec 2026Image-Based Prediction of Ventricular Tachycardias in Post-Myocarditis Patients: an International Multicenter Case-control Study · Centro Medico Teknon
- Dec 2026International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry · SCAD Alliance
- Dec 2026Prediction of ARrhythmic Events With Positron Emission Tomography II · State University of New York at Buffalo
- Dec 2026FEMART-1 Pilot Study · Emergency Medical Service, Prague
Who these studies take
Of the 63 Death, Sudden, Cardiac studies recruiting now, 41 (65%) set no upper age limit and 11 (17%) stop at 75 or younger. 21 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (24%) | 15 (24%) |
| 18 | 61 (97%) | 61 (97%) |
| 30 | 60 (95%) | 60 (95%) |
| 40 | 57 (90%) | 57 (90%) |
| 50 | 57 (90%) | 57 (90%) |
| 65 | 56 (89%) | 56 (89%) |
| 75 | 54 (86%) | 54 (86%) |
| 85 | 47 (75%) | 47 (75%) |
Across all 363 studies, recruiting or not: 16% stop at 75 or younger and 9% at 65; 24% take children; 1% are for women only and 3% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Death, Sudden, Cardiac studies take
Of 85 observational studies under Death, Sudden, Cardiac, half reached primary completion within 63 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 42 mo17–83 · 56 studies | — | 42 mo22–86 · 47 studies |
| Observational | 63 mo40–… · 85 studies | — | 74 mo42–… · 69 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
Studies
Recruiting first, then most recently updated. Showing 50 of 363. Browse all 363 → or search them.
- Evaluation of A Clinical Diagnostic Test for CRDSRecruitingNCT06188689Not applicable7 countries
- AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)RecruitingNCT058907162 countries
- Genetic Markers of Cardiovascular Disease in EpilepsyRecruitingNCT028248221 country
- Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or VenetoclaxRecruitingNCT057241211 country
- Cardiovascular Pre-participation Screening in Children and AdolescentsNot yet recruitingNCT078625041 country
- Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the AortaRecruitingNCT06705751Not applicable1 country
- Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data RepositoryRecruitingNCT051004201 country
- Epinephrine Dose: Optimal Versus Standard Evaluation TrialRecruitingNCT03826524Phase 41 country
- Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural AmericaRecruitingNCT06229418Not applicable1 country
- Mitral Valve Prolapse Arrhythmic RiskRecruitingNCT078308881 country
- Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective RegisterRecruitingNCT066421681 country
- Validation of Sudden Cardiac Arrest Risk Factors in Patients With CADRecruitingNCT074449313 countries
- Tampere Coronary Artery Disease and Sudden Cardiac Arrest StudyRecruitingNCT068044991 country
- Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care PathwaysEnrolling by invitationNCT077759761 country
- HeartStart HS1 Defibrillator* Event RegistryRecruitingNCT048407971 country
- HeartStart FRx Defibrillator Event RegistryRecruitingNCT042508571 country
- Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifesting as Aborted Sudden Cardiac DeathRecruitingNCT02845531Phase 41 country
- FEMART-1 Pilot StudyRecruitingNCT07596446Not applicable1 country
- National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter RegistryRecruitingNCT065461371 country
- PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)RecruitingNCT07421882Not applicable1 country
- Mayo AVC Registry and BiobankRecruitingNCT030492542 countries
- Developing a Digital Aid to Improve ICD DecisionsRecruitingNCT07084142Not applicable1 country
- A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)RecruitingNCT05885412Phase 11 country
- Digital MEDIcal TWIN for the Prediction of Arrhythmic Sudden Cardiac Death After a Myocardial InfarctionNot yet recruitingNCT07527494Not applicable1 country
- Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated CardiomyopathyRecruitingNCT075277151 country
- Early Evaluation of Exosome Multiomics and Clinical Prognosis in Patients With Sudden DeathRecruitingNCT068569931 country
- Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator ImplantationRecruitingNCT05665608Not applicable13 countries
- Functional Substrate-Only Guided VT AblationEnrolling by invitationNCT06464315Not applicable1 country
- Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac DeathNot yet recruitingNCT074764561 country
- AI-guided Prediction and Treatment of Cardiac ArrestNot yet recruitingNCT07452016Not applicable1 country
- Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic CardiomyopathyRecruitingNCT06174220Phase 21 country
- Loop Recorder Implantation in Patients With Mitral Annular DisjunctionRecruitingNCT07436962Not applicable1 country
- Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardioverter-Defibrillators (DUTCH-ICD)Not yet recruitingNCT07415642Not applicable1 country
- Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After MyectomyRecruitingNCT07372196Not applicable1 country
- Left Ventricular Structural Predictors of Sudden Cardiac DeathRecruitingNCT010766601 country
- Prospective Observational Study of the ICD in Sudden Cardiac Death PreventionRecruitingNCT007335901 country
- Imaging Techniques for Identifying Factors of Sudden Cardiac Death RiskRecruitingNCT001812331 country
- IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation RegistryEnrolling by invitationNCT045203477 countries
- Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic VariantEnrolling by invitationNCT070501601 country
- Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase InhibitorsRecruitingNCT05643235Not applicable1 country
- Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter DefibrillatorRecruitingNCT06964464Phase 41 country
- ASSURE WCD Clinical Evaluation - Post Approval Study (ACE-PAS)RecruitingNCT051354031 country
- Cardiac Magnetic Resonance - PROgnostic HEart Scar for Sudden Cardiac Death Prediction StudYRecruitingNCT071379361 country
- Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary SyndromeNot yet recruitingNCT071125471 country
- S-ICD Implantation: US Based Pilot StudyRecruitingNCT06771700Not applicable1 country
- Surgical Treatment of the Patients With Restrictive Phenotype of the Hypertrophic Cardiomyopathy Without LVOT ObstructionEnrolling by invitationNCT069776461 country
- Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active PeopleNot yet recruitingNCT070145791 country
- A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACMRecruitingNCT069766061 country
- Mechanisms And Prognosis of Stroke-Heart SyndromeRecruitingNCT069541031 country
- DNA Methylation in Brugada Syndrome and Risk of Sudden Cardiac DeathNot yet recruitingNCT06888271