Corneal Dystrophies, Hereditary clinical trials
The registry lists 31 studies for Corneal Dystrophies, Hereditary across more than 10 countries. 9 are recruiting or about to start. 16 of them are mainly about Corneal Dystrophies, Hereditary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 2 narrower conditions too, such as Fuchs' Endothelial Dystrophy: 142 studies, 43 open.
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Who runs them
Netherlands Institute for Innovative Ocular Surgery (2) · Vissum, Instituto Oftalmológico de Alicante (2) · Oregon Health and Science University (2) · Alcon Research (2) · National Eye Institute (NEI) (2) · Medical University of Vienna (1) · Icare Finland Oy (1) · Wenzhou Medical University (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy · Oregon Health and Science University
- Jul 2027High Resolution, High-speed Multimodal Ophthalmic Imaging · Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Aug 2027Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal Dystrophy · GenEditBio Limited
Who these studies take
Of the 7 Corneal Dystrophies, Hereditary studies recruiting now, 4 (57%) set no upper age limit and 1 (14%) stop at 75 or younger. 2 (29%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (14%) | 1 (14%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 6 (86%) | 6 (86%) |
| 75 | 6 (86%) | 6 (86%) |
| 85 | 6 (86%) | 6 (86%) |
Across all 31 studies, recruiting or not: 26% stop at 75 or younger and 19% at 65; 19% take children; 3% are for women only and 0% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic DiseasesRecruitingNCT064916151 country
- Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal DystrophyNot yet recruitingNCT07750678Phase 1/22 countries
- Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile SurgeryEnrolling by invitationNCT04642729Not applicable1 country
- Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in FranceRecruitingNCT057423211 country
- High Resolution, High-speed Multimodal Ophthalmic ImagingRecruitingNCT04129021Not applicable1 country
- OCT in Diagnosis of Irregular CorneasRecruitingNCT035048001 country
- Microsurgical Robot-assisted Corneal TransplantRecruitingNCT06844123Not applicable1 country
- FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United KingdomRecruitingNCT068817711 country
- Optical Coherence Tomography Guided Transepithelial Phototherapeutic KeratectomyRecruitingNCT01243931Not applicable1 country
- Correlation Between In-vivo Anatomy of Corneal Dystrophies as Assessed by High- Resolution Optical Coherence Tomography (OCT) Measurement and Histological ExaminationCompletedNCT03461991Not applicable1 country
- Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) Laser Treatment for Granular Corneal DystrophyTerminatedNCT06202651Not applicable1 country
- Air Optix® Night and Day® Aqua Therapeutic WearCompletedNCT059565351 country
- AONDA Therapeutic Indication Study ICompletedNCT058911061 country
- The Efficacy of Hyperemesis Gravidarum on Macular Thickness, Corneal Thickness and Intraocular Pressure in PregnancyCompletedNCT05927740Not applicable1 country
- Autologous Adipose-Derived Adult Stem Cell Implantation for Corneal Diseases (ADASCs-CT-CD)CompletedNCT05279157Phase 21 country
- Descemet Stripping (Automated) Endothelial Keratoplasty (DSEK or DSAEK)CompletedNCT00543660Not applicable1 country
- Descemet Membrane Endothelial Keratoplasty (DMEK)CompletedNCT00521898Not applicable1 country
- Keratoconus, Corneal Diseases and Transplant RegistryStatus unknownNCT041644071 country
- Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular DystrophyCompletedNCT00346853Phase 11 country
- Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem CellsCompletedNCT04484402Phase 1/21 country
- Defining the Operating Parameters for a Rebound-esthesiometerStatus unknownNCT04384094
- Comparative Results After DSAEK, UT-DSAEK and DMEK for Fuchs Endothelial Corneal DystophyCompletedNCT044245501 country
- Studies in Families With Corneal Dystrophy or Other Inherited Corneal DiseasesCompletedNCT003574353 countries
- Evaluation of Tomographic and Genetic Aspects of Keratoconus Patients Compared to Sounds CorneasCompletedNCT03071302Not applicable1 country
- Autologous Adipose-Derived Adult Stem Cell Transplantation for Corneal DiseasesStatus unknownNCT02932852Early Phase 11 country
- Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKPStatus unknownNCT02826174Not applicable1 country
- Study of the Prevalence of TGFBI Corneal DystrophiesStatus unknownNCT02746055
- Corneal Transplantation Guided by OCT RESCANStatus unknownNCT02736877Not applicable
- Laser Assisted Procedures in Penetrating KeratoplastyCompletedNCT02173847Not applicable1 country
- DSAEK- Postoperative Positioning and Transplant DislocationStatus unknownNCT01206127Not applicable1 country
- Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal SubjectsStatus unknownNCT010848501 country