Cone-Rod Dystrophies clinical trials
The registry lists 39 studies for Cone-Rod Dystrophies across more than 10 countries. 14 are recruiting or about to start. 10 of them are mainly about Cone-Rod Dystrophies (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
SparingVision (5) · National Eye Institute (NEI) (2) · Science Corporation (2) · MD Stem Cells (2) · Ascidian Therapeutics, Inc (2) · University Hospital, Lille (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · GenSight Biologics (1)
What is being tested here
Drugs under test in Cone-Rod Dystrophies studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cholesterol | 1 | 0 | 1 |
| Recombinant human nerve growth factor | 0 | 0 | 1 |
| Botulinum toxin type A | 0 | 1 | 1 |
| Interferon gamma-1b | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Dec 2026EyeConic: Qualification for Cone-Optogenetics · Institute of Molecular and Clinical Ophthalmology Basel
- Feb 2027Promising ROd-cone DYstrophy Gene therapY · SparingVision
- Mar 2027Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance · Okuvision GmbH
- Jul 2027Stem Cell Ophthalmology Treatment Study II · MD Stem Cells
- Aug 2027Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment · University of Waterloo
- Aug 2027Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH) · Ascidian Therapeutics, Inc
- Oct 2027Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa · GenSight Biologics
Who these studies take
Of the 13 Cone-Rod Dystrophies studies recruiting now, 10 (77%) set no upper age limit and 2 (15%) stop at 75 or younger. 5 (38%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (38%) | 5 (38%) |
| 18 | 12 (92%) | 12 (92%) |
| 30 | 13 (100%) | 13 (100%) |
| 40 | 13 (100%) | 13 (100%) |
| 50 | 13 (100%) | 13 (100%) |
| 65 | 13 (100%) | 13 (100%) |
| 75 | 11 (85%) | 11 (85%) |
| 85 | 11 (85%) | 11 (85%) |
Across all 39 studies, recruiting or not: 33% stop at 75 or younger and 26% at 65; 33% take children; 0% are for women only and 3% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 39 of 39. search them.
- Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision ImpairmentRecruitingNCT07341763Not applicable1 country
- A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)RecruitingNCT06789445Phase 1/21 country
- Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)RecruitingNCT064453221 country
- Natural History Study of Advanced RCDRecruitingNCT07854899Not applicable3 countries
- Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone DystrophyRecruitingNCT07807111Phase 1/23 countries
- Virtual Reality Mobility Assessment of Functional Vision in Retinal DiseaseRecruitingNCT04289571Phase 12 countries
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable3 countries
- Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome PatientsRecruitingNCT06395285Phase 13 countries
- Inherited Retinal Degenerative Disease RegistryRecruitingNCT024359401 country
- Adaptive Optics Imaging of Outer Retinal DiseasesRecruitingNCT053554151 country
- Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual PerformanceRecruitingNCT075489441 country
- EyeConic: Qualification for Cone-OptogeneticsRecruitingNCT052949787 countries
- Epidural Stimulation for Upper Extremity FunctionNot yet recruitingNCT06437548Not applicable
- Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)RecruitingNCT01773278Phase 21 country
- Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)Active, not recruitingNCT06467344Phase 1/21 country
- Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce SpasticityActive, not recruitingNCT05429736Not applicable1 country
- Study of New Mutations in Cone DisordersTerminatedNCT046582511 country
- Promising ROd-cone DYstrophy Gene therapYActive, not recruitingNCT05748873Phase 1/22 countries
- Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis PigmentosaActive, not recruitingNCT03326336Phase 1/23 countries
- Evaluation of Gingival Displacement MethodsCompletedNCT07122297Not applicable
- Prospective Natural History Study of Retinitis PigmentosaActive, not recruitingNCT04285398Not applicable2 countries
- A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)CompletedNCT02110225Phase 1/21 country
- Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]CompletedNCT04945772Phase 22 countries
- MNCs for Bone Marrow Failure After Malignant Diseases Children ChemotherapyStatus unknownNCT05628272Not applicable1 country
- Effect of Intraoperative Taping on the Control of Edema Resulting From StrippingStatus unknownNCT05534308Not applicable1 country
- Mother to Child Transmission of Antibody to Covid-19 The TRAB CoV-19 Study.CompletedNCT053052611 country
- Retrospective Natural History Study of Retinitis PigmentosaStatus unknownNCT039755431 country
- Supply With Micronutrients (Purine and Pyrimidine) in Infants: a Prospective and Observational StudyStatus unknownNCT035326331 country
- Outcome of Sub-inguinal Varicocelectomy on Normal Semen in Patients Complaining of Orchilagia With Normal SemenCompletedNCT038351431 country
- Stem Cell Ophthalmology Treatment StudyStatus unknownNCT01920867Not applicable1 country
- Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)TerminatedNCT02338973Phase 1/21 country
- Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal DystrophyCompletedNCT02670980Not applicable5 countries
- Impact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMSTerminatedNCT03561922Not applicable1 country
- Clinical Trial of a Serious Game for Individuals With SCI/DCompletedNCT02341950Not applicable1 country
- Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal DystrophyCompletedNCT01864486Not applicable3 countries
- Spinal Cord Stimulation Research StudyCompletedNCT007375811 country
- Autologous Stem Cells in Newborns With Oxygen DeprivationStatus unknownNCT01506258Not applicable1 country
- Intravesical Injection of Botulinum Toxin A Versus Saline for Neurogenic Detrusor OveractivityCompletedNCT01091727Phase 31 country
- IRIS PILOT - Extended Pilot Study With a Retinal Implant SystemStatus unknownNCT00427180Not applicable