Clostridium Infections: all 251 studies

Page 1 of 3. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.

• Epidemiology of Clostridioides Difficile Infection (CDI) in Long-term Care Facilities, Assessment of Professional Practices Related to CDI Risk Prevention, and Strategies for Improving Care.Not yet recruitingNCT07920627
• A Clinical Trial of Resistant Potato Starch for Gut MDRO DecolonizationNot yet recruitingNCT07792915Phase 2
• A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficileRecruitingNCT07649096Phase 1
• Lifestyle and Recurrent Clostridioides Difficile Infection (CDI)RecruitingNCT07613645Not applicable
• Long-Term Outcomes After CDI: FMT Versus Antibiotic-Only TreatmentNot yet recruitingNCT07569380
• ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile InfectionRecruitingNCT07513285Phase 2
• FMT Capsules for rCDIRecruitingNCT07458984Phase 3
• Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis PopulationRecruitingNCT07401680Phase 1
• Clostridioides Difficile: Understanding Responses and Treatment EffectsRecruitingNCT07374094
• Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal AntibodyRecruitingNCT07285213Phase 2
• Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill PatientsRecruitingNCT07221370Phase 2/3
• STOP-CDI: Efficacy of Fecal Microbiota Transplantation vs Fidaxomicin vs Vancomycin in Treating and Preventing Relapse of Clostridioides Difficile InfectionNot yet recruitingNCT07120490Not applicable
• Secondary Prevention of Clostridioides Difficile Using VancomycinRecruitingNCT06979609Phase 2/3
• A Flexible Clinical Trial to Test if Freeze-dried Fecal Microbiota Therapy Helps Treat Diarrhea-predominant Irritable Bowel Syndrome or Prevent Recurring C. Difficile Infections.Not yet recruitingNCT06948461Phase 2
• Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard TherapyRecruitingNCT06884748Early Phase 1
• Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain in Nephrology and Transplantation DepartmentRecruitingNCT06859437Not applicable
• CMTS0929 for Clostridioides Difficile InfectionNot yet recruitingNCT06836427Early Phase 1
• Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel DiseaseNot yet recruitingNCT06799039Early Phase 1
• Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel DiseaseNot yet recruitingNCT06794944Phase 4
• Study of Clostridioides Difficile in InfantsRecruitingNCT06788769
• Study on Clostridium Difficile Infection in InfantsRecruitingNCT06703918
• Virus as Treatment of C. Difficile Infection (VISION)Not yet recruitingNCT06398379Not applicable
• Intestinal Microbiota Transplantation in Patients Undergoing Colon ResectionRecruitingNCT06370884Phase 1
• A Study to Assess the Effect of Doctor's Biome Medical Food in Individuals With Clostridium Difficile InfectionNot yet recruitingNCT06367504Not applicable
• Safety Registry of a Fecal Microbiota Transplant CohortRecruitingNCT06311006
• Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk PatientsRecruitingNCT06306014Phase 1/2
• VE303 for Prevention of Recurrent Clostridioides Difficile InfectionRecruitingNCT06237452Phase 3
• Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative ColitisRecruitingNCT06228352
• Treatment of CDI and Recurrence With Fecal Microbiota Transplant Using PromicrobiomaNot yet recruitingNCT06107569Phase 3
• Washed Microbiota Transplantation for Clostridioides Difficile InfectionRecruitingNCT06106698
• Clostridioides Difficile Infection: Analyzing CLInic Evolution and Bacterial ClearanceRecruitingNCT06030245
• L. Plantarum 299v and Gut Microbiome, Diarrhoea, and Clostridioides Difficile Infection in Colorectal Cancer PatientsRecruitingNCT06019312Not applicable
• Xylitol Use for Decolonization of C. Difficile in Patients With IBDNot yet recruitingNCT05852587Phase 1
• Changes in Recipients Gut Microbiota After Fecal Microbiota TransplantationRecruitingNCT05739825
• Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD PatientsRecruitingNCT05714566
• Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile InfectionRecruitingNCT05709184Not applicable
• Clostridioides Difficile ColonisationRecruitingNCT05693077Phase 1
• Faecal Bacteriotherapy for Postantibiotic Diarrhoea in Critically Ill PatientsRecruitingNCT05430269Not applicable
• Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First RecurrenceRecruitingNCT05266807Phase 3
• FMT in Initial CDIRecruitingNCT05257538Not applicable
• Prevention of C.Difficile Infections With Oral Vancomycine in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantNot yet recruitingNCT05256693Phase 3
• Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile InfectionNot yet recruitingNCT04960306Phase 3
• Natural History of Clostridioides Difficile InfectionRecruitingNCT04801862
• Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)RecruitingNCT04305769Phase 2
• Safety and Efficacy of Fecal Microbiota TransplantationRecruitingNCT04014413Not applicable
• Rescue Fecal Microbiota Transplantation for National Refractory Intestinal InfectionsRecruitingNCT03895593
• Fecal Microbiota Transplantation (FMT): PRIM-DJ2727AvailableNCT03786900
• Fecal Microbiota Transplantation (FMT) for Clostridium DifficileRecruitingNCT03712722
• Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium DifficileRecruitingNCT03562741Not applicable
• Fecal Microbiota Transplant National RegistryRecruitingNCT03325855
• Fecal Microbiota Transplantation for C Diff InfectionRecruitingNCT01905709Not applicable
• The Clostridioides Difficile Trial of REC-3964TerminatedNCT06536465Phase 2Results posted
• Bezlotoxumab Yielded Outcomes by Addressing Personalized Needs in Clostridioides Difficile InfectionCompletedNCT05304715Phase 2Results posted
• Primary or Recurrent Clostridioides Difficile Infection Treatment With Capsules of Lyophilised Faecal Microbiota vs FidaxomicinCompletedNCT05201079Phase 3Results posted
• A Trial of CP101 for the Prevention of Recurrent CDI (PRISM4)TerminatedNCT05153499Phase 3Results posted
• High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in OncologyCompletedNCT04940468Not applicableResults posted
• Exploratory Study to Assess Delivery of LMN-201 Components Via Enteric Capsules in the Gut of Individuals With OstomiesCompletedNCT04893239Phase 1Results posted
• Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent SubjectsTerminatedNCT04802837Phase 3Results posted
• Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile InfectionCompletedNCT04781387Phase 2Results posted
• Prevention of Recurrent Clostridium Difficile Infection (CDI) in Patients With Inflammatory Bowel Disease (IBD).TerminatedNCT04626947Phase 4Results posted
• ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile InfectionCompletedNCT04247542Phase 2Results posted
• Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 YearsCompletedNCT04026009Phase 1Results posted
• Penn Microbiome Therapy for Recurrent Clostridium Difficile InfectionTerminatedNCT03973697Phase 2Results posted
• Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)TerminatedNCT03970200Phase 2Results posted
• Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS)CompletedNCT03931941Phase 3Results posted
• Lyophilized Fecal Microbiota Transplantation for Recurrent Clostridioides Difficile InfectionCompletedNCT03834038Not applicableResults posted
• ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDICompletedNCT03829475Phase 2Results posted
• Fecal Microbiota Transplant for Primary CDITerminatedNCT03795233Phase 1/2Results posted
• Phase 2 Study of VE303 for Prevention of Recurrent Clostridioides Difficile InfectionCompletedNCT03788434Phase 2Results posted
• The GRAFT Study: Gut RecolonizAtion by Fecal TransplantationCompletedNCT03621657Phase 2Results posted
• Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant RecipientsTerminatedNCT03617445Phase 2Results posted
• Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile InfectionCompletedNCT03595553Phase 3Results posted
• Safety and Efficacy of FMT in Individuals With One or More Recurrences of Clostridium Difficile Associated Disease (CDAD)TerminatedNCT03548051Phase 1/2Results posted
• COMBACTE-CDI Understanding the Burden of C. Difficile InfectionCompletedNCT03503474Results posted
• Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile InfectionCompletedNCT03497806Phase 2Results posted
• Efficacy of Oral Vancomycin Prophylaxis for Prevention of Recurrent Clostridium Difficile InfectionCompletedNCT03462459Phase 2Results posted
• TOX NEG Trial: Clostridium Difficile Diagnosis and TreatmentCompletedNCT03388268Phase 4Results posted
• Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated InfectionCompletedNCT03349268Not applicableResults posted
• Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)CompletedNCT03244644Phase 3Results posted
• ECOSPOR IV: An Open-Label Study Evaluating SER-109 in Recurrent Clostridioides Difficile InfectionCompletedNCT03183141Phase 3Results posted
• ECOSPOR III - SER-109 Versus Placebo in the Treatment of Adults With Recurrent Clostridium Difficile InfectionCompletedNCT03183128Phase 3Results posted
• Bezlotoxumab (MK-6072) Versus Placebo in Children With Clostridium Difficile Infection (CDI) (MK-6072-001)CompletedNCT03182907Phase 3Results posted
• Efficacy, Safety, and Tolerability Study of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Recurrent C. DiffCompletedNCT03110133Phase 2Results posted
• The ICON Study: Outcomes After FMT for Patients With IBD and CDICompletedNCT03106844Phase 1/2Results posted
• Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)TerminatedNCT03105479Phase 2/3Results posted
• Clostridium Difficile Vaccine Efficacy TrialCompletedNCT03090191Phase 3Results posted
• Vancomycin for C Difficile NAAT+/EIA- Hematology Oncology PatientsCompletedNCT03030248Phase 2Results posted
• Microbiota or Placebo After Antimicrobial Therapy for Recurrent C. Difficile at Home (MATCH)TerminatedNCT03005379Phase 2/3Results posted
• Screening to Prophylax Against Clostridium Difficile Infection -CompletedNCT02996487Phase 4Results posted
• Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile StrainsCompletedNCT02968758Not applicableResults posted
• Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk AntibioticsCompletedNCT02951702Phase 4Results posted
• Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of KefirTerminatedNCT02707198Phase 2Results posted
• A Comparison of Fidaxomicin and Vancomycin in Patients With CDI Receiving Antibiotics for Concurrent InfectionsCompletedNCT02692651Phase 4Results posted
• Microbiota Restoration Therapy for Recurrent Clostridium Difficile InfectionCompletedNCT02589847Phase 2Results posted
• A Study of SYN-004 for the Prevention of C.Diff in Patients With a LRTICompletedNCT02563106Phase 2Results posted
• Stress Ulcer Prophylaxis in the Intensive Care UnitCompletedNCT02467621Phase 4Results posted
• Efficacy of 30-day Duration of Fidaxomicin for Recurrent C. Difficile InfectionTerminatedNCT02395848Phase 3Results posted
• FMT Versus Antimicrobials for Initial Treatment of Recurrent CDITerminatedNCT02255305Phase 2Results posted
• Prospective Observational Study of Clostridium Difficile Infection in Asian Pacific CountriesCompletedNCT02223715Results posted
• A Study to Investigate the Safety and Efficacy of Fidaxomicin (Oral Suspension or Tablets) and Vancomycin (Oral Liquid or Capsules) in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD)CompletedNCT02218372Phase 3Results posted

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