Clinical Deterioration clinical trials
The registry lists 47 studies for Clinical Deterioration across more than 10 countries. 15 are recruiting or about to start. 30 of them are mainly about Clinical Deterioration (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Bispebjerg Hospital (3) · Shengjing Hospital (3) · Erzincan University (2) · Eske Kvanner Aasvang (2) · University Hospital Bispebjerg and Frederiksberg (2) · Fundacion Miguel Servet (2) · Hospital Galdakao-Usansolo (1) · Consorci Sanitari de l'Alt Penedès i Garraf (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Nov 2026MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training · National University of Singapore
- Dec 2026A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning · AgileMD, Inc.
- Dec 2026Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography · Shengjing Hospital
- Dec 2026A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA. · Shengjing Hospital
- Jan 2027Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-Pediatric · University of Michigan
- Jun 2027Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission · Copenhagen University Hospital at Herlev
- Sep 2027MRSI Evaluation for Minor Stroke With Large Vessel Occlusion · Shanghai 6th People's Hospital
- Nov 2027Multicomponent Exercise to Prevent Hospitalization-Associated Disability · Fundacion Miguel Servet
Who these studies take
Of the 9 Clinical Deterioration studies recruiting now, 7 (78%) set no upper age limit and 1 (11%) stop at 75 or younger. 1 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (11%) | 1 (11%) |
| 18 | 8 (89%) | 8 (89%) |
| 30 | 7 (78%) | 7 (78%) |
| 40 | 7 (78%) | 7 (78%) |
| 50 | 7 (78%) | 7 (78%) |
| 65 | 7 (78%) | 7 (78%) |
| 75 | 8 (89%) | 8 (89%) |
| 85 | 8 (89%) | 8 (89%) |
Across all 47 studies, recruiting or not: 9% stop at 75 or younger and 6% at 65; 6% take children; 0% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Clinical Deterioration studies take
Of 18 observational studies under Clinical Deterioration, half reached primary completion within 10 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo12–23 · 15 studies | — | — |
| Observational | 10 mo6–… · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 47 of 47. search them.
- The Orientation Intervention to Rapid Response Teams (ORIENT-RRT) Study: A Quasi-Experimental StudyRecruitingNCT07897851Not applicable1 country
- MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration TrainingNot yet recruitingNCT07872735Not applicable
- Repeated Examinations for Typing Pulmonary EmbolismRecruitingNCT074910941 country
- Multimodal Physiologic State Intelligence StudyEnrolling by invitationNCT078141181 country
- Hospital-Onset Sepsis Systematic Detection and Structured InterventionsNot yet recruitingNCT07804251Not applicable1 country
- Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital AdmissionRecruitingNCT07756554Not applicable1 country
- Cognitive Outcomes in BAD-related StrokeNot yet recruitingNCT077611821 country
- Multicomponent Exercise to Prevent Hospitalization-Associated DisabilityRecruitingNCT07707310Not applicable1 country
- Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm ValidationNot yet recruitingNCT07649642Not applicable1 country
- Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary AngiographyRecruitingNCT054822691 country
- A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA.RecruitingNCT050987691 country
- Wireless Assessment of Respiratory and Circulatory Distress - EuropeNot yet recruitingNCT07451249Not applicable4 countries
- Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-PediatricRecruitingNCT07304050Not applicable1 country
- MRSI Evaluation for Minor Stroke With Large Vessel OcclusionRecruitingNCT064572171 country
- Early Neurological Deterioration in Recent Small Subcortical InfarctionRecruitingNCT056799861 country
- Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older AdultsCompletedNCT06634147Not applicable1 country
- Feasibility and Initial Clinical Impressions of Predictive Monitoring Integrated With the RACE TeamCompletedNCT05108376Not applicable1 country
- Continuous Monitoring of Patients in and After the Acute Admission Ward to Optimize Clinical PathwaysCompletedNCT05181111Not applicable1 country
- EWSs and 28-Day Mortality in Geriatric ED PatientsCompletedNCT075773491 country
- Personalised Real-time Interoperable Sepsis Monitoring (PRISM)WithdrawnNCT062381801 country
- Continuous Monitoring of Vital Signs at Home (WARD HOME II)CompletedNCT060778511 country
- An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism PatientsActive, not recruitingNCT054812421 country
- vHDU Phase 5: Impact of an Ambulatory Monitoring System on Deterioration Detection and Clinical OutcomesCompletedNCT05118477Not applicable1 country
- Observational Study of Early Postoperative Deterioration and ComplicationsCompletedNCT060138911 country
- Wearable Wireless Respiratory Monitoring System That Detects and Predicts Opioid Induced Respiratory DepressionCompletedNCT064424881 country
- A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine LearningActive, not recruitingNCT05893420Not applicable1 country
- Image-based Remote Monitoring in Cardiac Surgery PatientsCompletedNCT060993271 country
- Automated Alerts of Patient Deterioration vs. Routine Monitoring of High-risk Patients Admitted to Medical WardsCompletedNCT04661748Not applicable1 country
- CSAPG Early Warning ScoreCompletedNCT04905095Not applicable1 country
- Realtime Streaming Clinical Use Engine for Medical EscalationCompletedNCT04026555Not applicable1 country
- Clinical Deterioration Early Warning System ScoreCompletedNCT064993761 country
- Predictive Monitoring - IMPact in Acute Care Cardiology TrialActive, not recruitingNCT04359641Not applicable1 country
- VitalThings Guardian Contactless MonitoringCompletedNCT060832721 country
- Evaluation of the Modified Early Warning Scoring SystemCompletedNCT05575531Not applicable1 country
- Continuous and Wireless Vital Sign Monitoring in Patients at Home After Acute Medical AdmissionCompletedNCT055362061 country
- Continuous Wireless Monitoring of Vital Signs and Automated Alerts of Patient Deterioration in Patients Admitted With COVID-19 InfectionTerminatedNCT04724681Not applicable1 country
- Clinical Outcomes After Implementation of COntinuous Vital Sign Monitoring On the General Ward.CompletedNCT041896531 country
- WARD-Home - Continuous Monitoring of Vital Parameters After DischargeCompletedNCT052235041 country
- Early Identification of Clinical Deterioration Using a Wearable Monitoring DeviceCompletedNCT042203591 country
- Outcomes of Digital Alerting Systems in Secondary CareStatus unknownNCT046387381 country
- Individual Early Warning Score (I-EWS)CompletedNCT03690128Not applicable1 country
- Early Warning Systems, Risk of Early Clinical DeteriorationStatus unknownNCT039127011 country
- Usefulness of Early Warning Systems in Detecting Early Clinical Deterioration After Intensive Care DischargeStatus unknownNCT039107771 country
- Calprotectin I Serum as a Diagnostic MarkerCompletedNCT034744841 country
- Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary DiseaseCompletedNCT034678151 country
- Early Warning System for Clinical Deterioration on General Hospital WardsCompletedNCT01280942Not applicable1 country
- Understanding Physician Signout Risk PerceptionCompletedNCT026488281 country