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RecruitingNCT07897851The ORIENT-RRTUpdated Oct 27, 2026

The Orientation Intervention to Rapid Response Teams (ORIENT-RRT) Study: A Quasi-Experimental Study

An interventional study of Orientation day with rapid response nurse in Deterioration, Clinical, sponsored by University of Colorado, Denver. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-27.

Sponsored by University of Colorado, Denver · Not applicable, Interventional, and Other

Updated Oct 27, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
300
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.

Read the detailed description

New graduate nurses (NGN) are faced with multiple challenges as they orient to their role as a registered nurse. Acute care NGN are charged with caring for an increasingly complex patients with high acuity. When a patient begins to decline in the inpatient setting, it is termed patient deterioration. Patient deterioration is defined in differing ways depending on the disposition of the patient and their particular clinical picture, but the term generally refers to a patient who is declining in health rapidly due to acute adverse events during their hospitalization. This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.

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Conditions studied

  • Deterioration, Clinical

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Keywords

  • confidence
  • knowledge
  • nursing practice
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In context

Clinical Deterioration

51 studies on the registry are indexed under Clinical Deterioration; 15 are open to participants now.

This study's planned enrollment of 300 is close to the median of 300 across 25 interventional studies indexed under Clinical Deterioration.

Browse Clinical Deterioration studies →

Lead sponsor

University of Colorado, Denver is the lead sponsor of 1,540 studies on the registry; 319 are open to participants now.

Of its 146 completed or terminated interventional studies of FDA-regulated products, 92 (63%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • New graduate nurses hired onto an acute care unit at University of Colorado Hospital, Medical Center of the Rockies, and Poudre Valley Hospital

Exclusion criteria

Exclusion Criteria:

  • New graduate nurses who are not employed on an acute care unit at the three study hospital at UCHealth
  • New graduate nurses who have completed clinical orientation or started orientation prior to this study commencing
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Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
300 participants (estimated)

Study arms

  • Experimental
    Intervention

    This group of newly graduate will spend one day of orientation with a rapid response nurse

    Other: Orientation day with rapid response nurse

  • No intervention
    Control

    This group of new graduate nurses will receive routine orientation

Interventions

  • OtherOrientation day with rapid response nurse

    This orientation day is spending attending rapid responses with a rapid response nurse.

    Also known as: orientation

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What researchers measure

Primary outcomes

  1. Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale (CARED)

    Assessment of 1) beliefs about rapid response systems, 2) fears about escalating care, and 3) perceived confidence in responding. This is a 22-item scale which uses a 5-point Likert scale. Scores ranges from 22-110. Higher scores indicate that participants have increase confidence that rapid response teams will support them, decreased fears about engaging with rapid response teams, and increase confidence with responding to deteriorating patients.

    Time frame: The participants will complete a baseline survey (pre-survey) at enrollment at the start of their orientation. Approximately 10-12 weeks later, the participants will complete a post-survey after they have completed orientation.

  2. Activation of Rapid Responses

    Assessment of whether new graduate nurse or virtual intensive care unit initiated rapid response. New graduate nurse initiation of rapid response demonstrates frontline nurse detected the patient deterioration versus a late recognition by the virtual intensive care unit.

    Time frame: Participant's engagement with the rapid response team will be examined from the beginning of their orientation through the end of their first year (52 weeks in total).

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Study locations

1 of 1 sites recruiting
  • UCHealth
    Aurora, Colorado 80045, United States
    Recruiting
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References and documents

Publications

  • Chua WL, Tee A, Hassan NB, Jones D, Tam WWS, Liaw SY. The development and psychometric evaluation of the Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale. Aust Crit Care. 2021 Jul;34(4):340-349. doi: 10.1016/j.aucc.2020.08.008. Epub 2020 Oct 23. PubMed 33250402 ↗
  • Orique SB, Despins L, Wakefield BJ, Erdelez S, Vogelsmeier A. Perception of clinical deterioration cues among medical-surgical nurses. J Adv Nurs. 2019 Nov;75(11):2627-2637. doi: 10.1111/jan.14038. Epub 2019 Aug 27. PubMed 31012138 ↗
  • Murray M, Sundin D, Cope V. New graduate nurses' clinical safety knowledge by the numbers. J Nurs Manag. 2019 Oct;27(7):1384-1390. doi: 10.1111/jonm.12819. Epub 2019 Jul 22. PubMed 31230379 ↗
  • Jones D, Mitchell I, Hillman K, Story D. Defining clinical deterioration. Resuscitation. 2013 Aug;84(8):1029-34. doi: 10.1016/j.resuscitation.2013.01.013. Epub 2013 Jan 31. PubMed 23376502 ↗
  • Geist NC, Browning M, Messick A. Development of a Critical Reflection Mentorship Program to Enhance Critical Thinking Among Novice Nurses. J Contin Educ Nurs. 2024 Sep;55(9):456-460. doi: 10.3928/00220124-20240718-01. Epub 2024 Aug 1. PubMed 39088688 ↗

Individual participant data

Plan to share: No

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 27, 2026
Show all 1 update
  1. Oct 27, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

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Registry details

Key details

Study ID
NCT07897851
Responsible party
Maureen Varty (Principal Investigator, University of Colorado Health) — Principal investigator
First posted
Oct 27, 2026
Start date
Sep 28, 2026
Primary completion
Sep 30, 2028 (estimated)
Completion
Dec 31, 2028 (estimated)
Last update
Oct 27, 2026

Study contacts

Maureen Varty, PhD, RN
Contact
maureen.varty@uchealth.org
720-848-6648

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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