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Active, not recruitingNCT05481242Updated Mar 11, 2026

An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism Patients

An observational study in Pulmonary Embolism and Thrombosis and Deterioration, Clinical, sponsored by Shengjing Hospital. Active, not recruiting at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-03-11.

Sponsored by Shengjing Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
2,000
Ages
18 Years and older
Sex
All
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Study summary

This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into hospital.

Read the detailed description

This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into hospital.

Eligible patients were collected to develop and evaluate a simple predictive model for predicting the adverse outcomes. The discriminatory power was evaluated by comparing the nomogram to the established risk stratification systems. The consistency of the nomogram was evaluated using the validation cohort.

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Conditions studied

  • Pulmonary Embolism and Thrombosis
  • Deterioration, Clinical
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In context

Pulmonary Embolism

739 studies on the registry are indexed under Pulmonary Embolism; 159 are open to participants now.

This study's planned enrollment of 2,000 is above the median of 392 across 324 observational studies indexed under Pulmonary Embolism.

Browse Pulmonary Embolism studies →

Lead sponsor

Shengjing Hospital is the lead sponsor of 124 studies on the registry; 57 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Chinese

Inclusion criteria

  • age of ≥ 18 years and a pulmonary embolism diagnosis based on CT pulmonary angiography

Exclusion criteria

Exclusion Criteria:

  • pregnancy
  • reception of reperfusion treatment before admission
  • missing data regarding CT parameters, echocardiography, cardiac troponin I (c-Tn I), and N-terminal-pro brain natriuretic peptide (NT-pro BNP) levels.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
2,000 participants (estimated)
Patient registry
No

Interventions

  • Otherretrospective observational study

    retrospective observational study

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What researchers measure

Primary outcomes

  1. Adverse outcomes

    The endpoints of deterioration in this study were defined as the occurrence of any adverse clinical outcomes from medical records and follow-up within 30 days of admission such as death, mechanical ventilation, cardiopulmonary resuscitation, and the need for life-saving vasopressor or reperfusion treatment .In each centre, the researchers for evaluating endpoints were blind to collect and to measure study parameters.

    Time frame: 30 days

Secondary outcomes

  1. Adverse outcomes

    The endpoints of deterioration in this study were defined as the occurrence of any adverse clinical outcomes from medical records and follow-up within 2 years of admission such as death, mechanical ventilation, cardiopulmonary resuscitation, and the need for life-saving vasopressor or reperfusion treatment .In each centre, the researchers for evaluating endpoints were blind to collect and to measure study parameters.

    Time frame: 2 years

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Study locations

1 site
  • Shenjing Hospital of CHINA MEDICAL UNIVERSITY
    Shenyang, Liaoning, China
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05481242
Lead sponsor
Shengjing Hospital
Responsible party
YIZHUO GAO (Doctor, Shengjing Hospital) — Principal investigator
First posted
Aug 1, 2022
Start date
Jan 1, 2011
Primary completion
Jan 31, 2021
Completion
Dec 31, 2026 (estimated)
Last update
Mar 11, 2026

Study contacts

DONG JIA
principal investigator · Shenjing Hospital of CHINA MEDICAL UNIVERSITY

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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