Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
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Exelixis clinical trials
The registry lists 57 studies whose lead sponsor is Exelixis. 12 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 23, 2026.
Keep track of what changes. Save the Exelixis studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
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Registry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Exelixis.
- Exelixis57 studiesSame company
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Focus areas
Conditions Exelixis leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 50 of 57. Browse all 57 →
- Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine TumorsRecruitingNCT06943755Phase 2/3
- A Study of Zanzalintinib in Participants With Recurrent or Progressive MeningiomaRecruitingNCT07428616Phase 2
- Study of XB010 in Subjects With Solid TumorsRecruitingNCT06545331Phase 1
- Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsRecruitingNCT05176483Phase 1
- Zanzalintinib and Pembrolizumab in First-Line Maintenance for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)Not yet recruitingNCT07845786Phase 2
- Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual DiseaseRecruitingNCT07750158Phase 3
- Study of Zanzalintinib in Children and Adolescents With Relapsed or Refractory Solid TumorsNot yet recruitingNCT07773454Phase 1
- Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored StudyEnrolling by invitationNCT07620574Phase 3
- A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid TumorsRecruitingNCT06952010Phase 1
- A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid TumorsRecruitingNCT07123103Phase 1
- A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid TumorsRecruitingNCT05932862Phase 1
- Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)RecruitingNCT06962332Phase 1
- Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell CarcinomaActive, not recruitingNCT03937219Phase 3
- A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid CancerActive, not recruitingNCT01896479Phase 4
- A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted TherapyActive, not recruitingNCT03690388Phase 3
- Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid TumorsActive, not recruitingNCT03170960Phase 1
- Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell CarcinomaActive, not recruitingNCT05678673Phase 3
- Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal CancerActive, not recruitingNCT05425940Phase 3
- Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second RelapseTerminatedNCT01068782Phase 2
- A Study of XL184 (Cabozantinib) With or Without Erlotinib in Subjects With Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00596648Phase 1/2
- Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPCTerminatedNCT01995058Phase 2
- Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPCActive, not recruitingNCT04446117Phase 3
- Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer TherapyActive, not recruitingNCT03755791Phase 3
- Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT06082167Phase 2/3
- A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid TumorsTerminatedNCT06630247Phase 1
- Study of Zanzalintinib (XL092) + AB521 and Zanzalintinib + AB521 + Nivolumab in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Other Advanced Solid Tumors (STELLAR-009)TerminatedNCT06191796Phase 1
- Study of XB002 in Subjects With Solid Tumors (JEWEL-101)CompletedNCT04925284Phase 1
- A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid TumorsActive, not recruitingNCT03845166Phase 1
- Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101)TerminatedNCT04726332Phase 1
- Study of Cabozantinib (XL184) in Adults With Advanced MalignanciesCompletedNCT00940225Phase 2
- Study of XL184 (Cabozantinib) in Adults With Glioblastoma MultiformeCompletedNCT00704288Phase 2
- Study of XL114 in Subjects With Non-Hodgkin's LymphomaTerminatedNCT05144347Phase 1
- Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior SorafenibCompletedNCT01908426Phase 3
- A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell CarcinomaCompletedNCT01865747Phase 3
- Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid CancerCompletedNCT00704730Phase 3
- Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate CancerTerminatedNCT01522443Phase 3
- Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100CompletedNCT01605227Phase 3
- A Phase 1 Study of XL019 in Adults With Polycythemia VeraTerminatedNCT00595829Phase 1
- A Study of XL844 Administered as a Single Agent and in Combination With Gemcitabine in Adults With Advanced MalignanciesTerminatedNCT00475917Phase 1
- Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic LeukemiaTerminatedNCT00464113Phase 1
- Study of XL228 Administered Intravenously to Subjects With Advanced MalignanciesTerminatedNCT00526838Phase 1
- Safety Study of Pharmacokinetics of XL888 in Adults With Solid TumorsTerminatedNCT00796484Phase 1
- Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid TumorsWithdrawnNCT00704392Phase 1
- Dose-Finding Study of Cabozantinib (XL184) in Japanese Subjects With Advanced CancerCompletedNCT01553656Phase 1
- A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal FunctionCompletedNCT01761773Phase 1
- Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With GlioblastomaCompletedNCT00960492Phase 1
- Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult SubjectsCompletedNCT01493869Phase 1
- A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid TumorsCompletedNCT01100619Phase 1
- A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or SunitinibCompletedNCT00570635Phase 2
- Study of XL184 (Cabozantinib) in Adults With Advanced MalignanciesCompletedNCT00215605Phase 1