beta-Thalassemia: all 312 studies
Page 2 of 4. Open to participants first (73), then studies with results posted, then the rest; newest registration first within each.
- A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.CompletedNCT00390858Phase 2Results posted
- Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia PatientsCompletedNCT00303329Phase 2Results posted
- Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration)CompletedNCT00171301Phase 4Results posted
- An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron OverloadCompletedNCT00171210Phase 3Results posted
- Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac DiseasesTerminatedNCT00115349Phase 2Results posted
- Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasActive, not recruitingNCT00061568Phase 1/2Results posted
- Effect of Omega 3 Fatty Acids on Heart and Liver in Beta Thalassemia PatientsCompletedNCT07863791Phase 2
- Evaluate the Efficacy and Safety of Irochel for the Management of Iron Overload in Thalassemia Patients in Comparison With DeferoxamineCompletedNCT07782931Phase 3
- A Study to Evaluate Luspatercept Utilization in Patients With Lower Risk Myelodysplastic Syndromes or Beta-thalassemiaTerminatedNCT07681440
- Expanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell DiseaseTemporarily not availableNCT07640815
- Iron Accumulation in Erythrocytes in PatientsCompletedNCT07486531
- Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell DiseaseTerminatedNCT07431398Phase 1
- Prevalence of Hemoglobinopathies Associated With Significant Hb Variants in the Chattogram Region of BangladeshCompletedNCT07207551
- Elastography vs Iron Regulators in the Diagnosis of Hepatic Fibrosis- Iron Overload in Children With Beta- ThalassemiaCompletedNCT07153926
- Impact of Virtual Reality on Pain and Anxiety During Intravenous Cannulation Procedures Among Thalassemia Patients in UAE.CompletedNCT07099196Not applicable
- Growth Evaluation, Health Promotion, and Clinical Management in Children and Adolescents With ThalassemiaActive, not recruitingNCT06931912Not applicable
- Study to Evaluate the Long- Term Safety and Efficacy of Luspatercept in Subjects Who Received at Least One Dose of Luspatercept in the Compassionate Use PhaseActive, not recruitingNCT06913634
- To Evaluate Long- Term Safety and Efficacy of LuspaterceptActive, not recruitingNCT06875219
- ERN-EuroBloodNet Registry on Patients with Rare Red Blood Cell Defects and COVID-19CompletedNCT06831799
- Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-ThalassemiaCompletedNCT06606886Phase 4
- A Real-World Study of β-Thalassemia Major Treatment With Luspatercept in TaiwanActive, not recruitingNCT06596642
- Vitamin E Supplementation for Children With Transfusion Dependent Beta Thalassemia on Different Iron Chelation RegimenCompletedNCT06509581Not applicable
- Long Term Beta Thalassemia Treatment: Findings From The Extension PeriodActive, not recruitingNCT06490601Phase 2
- Comparison of Deferasirox and Desferoxamine in Patients of β-Thalassemia Major With Iron OverloadCompletedNCT06468423Not applicable
- A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the BodyActive, not recruitingNCT06421636Phase 2
- An Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-ThalassemiaActive, not recruitingNCT06308159Phase 1/2
- A Safety and Efficacy Study Evaluating CS-101 in Subjects With β-Thalassemia MajorCompletedNCT06291961Phase 1
- Comparison Of Efficacy And Safety Of Thalidomide Vs Hydroxyurea In Thalassemia Patients: A Single-Centre Pilot Study.CompletedNCT06239389Phase 2
- Thalidomide and Hydroxyurea Combination in β-Thalassemia PatientsCompletedNCT06153784Phase 2/3
- Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia PatientsCompletedNCT06146478Phase 3
- Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia MajorCompletedNCT06065189Early Phase 1
- A Clinical Study Evaluating the Safety and Efficacy of CS-101 in Treating Subjects With β-thalassemiaCompletedNCT06024876Early Phase 1
- Cardiac Management of Patients With Thalassemia Minor and Breast CancerCompletedNCT05960214
- A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in IndiaActive, not recruitingNCT05891249Phase 4
- Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.Active, not recruitingNCT05860595Not applicable
- NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia MajorStatus unknownNCT05777733Phase 1
- A Study to Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects with Transfusion Dependent Β-Thalassaemia.TerminatedNCT05752123Not applicable
- Red Blood Cells From Umbilical Cord for Transfusion of Preterm InfantsCompletedNCT05612919Not applicable
- Clinical Study to Evaluate the Possible Efficacy and Safety of L- Carnitine and Sildenafil in Children Having Beta Thalassemia With Increased Tricuspid Regurgitant Jet VelocityStatus unknownNCT05584956Phase 3
- Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-ThalassemiaActive, not recruitingNCT05577312Phase 1/2
- A Study to Evaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia.Active, not recruitingNCT05567458Phase 2
- Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemiaStatus unknownNCT05494333
- Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta ThalassemiaCompletedNCT05469230
- The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world StudyStatus unknownNCT05462548Phase 4
- EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)Active, not recruitingNCT05444894Phase 1/2
- Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem CellsSuspendedNCT05442346Not applicable
- The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University HospitalsStatus unknownNCT05370677
- Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-ThalassemiaActive, not recruitingNCT05357482Phase 1/2
- Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)Active, not recruitingNCT05356195Phase 3
- A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)Active, not recruitingNCT05353647Phase 2
- Study on the Effect of Different Risk Factors on the Growth Parameters of Thalassemic Patients in Assiut (AUCH)Status unknownNCT05303506
- Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.Active, not recruitingNCT05145062
- The Prevelence of HBB c.93-21 G-A in β Thalassemia PatientsStatus unknownNCT05133388
- Clinical Experience of Thalidomide in Thalassemic PatientsCompletedNCT05132270Phase 2/3
- Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.Status unknownNCT05105659
- A Study Evaluating the Safety and Efficacy of the BD211 Drug Product in β-Thalassemia Major ParticipantsCompletedNCT05015920Not applicable
- A Study of Etavopivat in Patients With Thalassemia or Sickle Cell DiseaseCompletedNCT04987489Phase 2
- Study to Evaluate Additional Risk Minimisation Measures (aRMMs) for REBLOZYL Among Healthcare Professionals (HCPs)CompletedNCT04973280
- Thrombin Generation in Beta-thalassemia MajorStatus unknownNCT04962984Not applicable
- Iron Status in BTM With Blood TransfusionStatus unknownNCT04947540
- Efficacy and Safety Study of Multiple Doses of VIT-2763 in Adults With Transfusion-dependent Beta-thalassemiaWithdrawnNCT04938635Phase 2
- A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-ThalassaemiaTerminatedNCT04925206Phase 1
- Genetic Variants Affecting the Clinical Severity of Beta ThalassemiaStatus unknownNCT04918056
- Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe HemoglobinopathiesWithdrawnNCT04776850Early Phase 1
- A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic SyndromeCompletedNCT04718844Phase 1
- The Role of OCTA in Patients Affected by Beta ThalassemiaCompletedNCT04582110
- Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological DiseasesCompletedNCT04526405
- Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent β-ThalassaemiaCompletedNCT04390971Not applicable
- Congenital Heart Surgery in Pediatric Patients With Beta-Thalassemia MajorCompletedNCT04367701
- PK of SOF/LED in HCV - Infected Adolescents With Haematological DisordersStatus unknownNCT04353986Phase 3
- Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major ThalassemiaCompletedNCT04292314Phase 2/3
- The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia MajorCompletedNCT04260516Phase 1
- Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)Status unknownNCT04247750Phase 2
- Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem CellsCompletedNCT04211480Not applicable
- β-globin Restored Autologous HSC in β-thalassemia Major PatientsTerminatedNCT04205435Phase 1/2
- Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124WithdrawnNCT04176653Phase 1
- Quantitative Susceptibility Mapping (QSM) to Guide Iron Chelating TherapyCompletedNCT04171635
- Phase 2a Pilot Study of NBMI Treatment in Patients With Beta Thalassemia Major, Requiring Iron ChelationCompletedNCT04092205Phase 2
- Choroidal Thickness in Beta-thalassemia PatientsCompletedNCT04067258
- Safety Study for Beta Thalassemia Subjects on PTG-300CompletedNCT04054921Phase 2
- Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical StudyCompletedNCT04009525Phase 4
- Apotransferrin in Patients With β-thalassemiaTerminatedNCT03993613Phase 2
- Impact of the Preparation Method of Red Cell Concentrates on Transfusion Indices in Thalassemic PatientsCompletedNCT03992001Phase 4
- Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C VirusCompletedNCT03961828Phase 4
- Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia MajorStatus unknownNCT03951818
- The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia MajorCompletedNCT03948737Not applicable
- Anthropometric Measurements in Children Having Transfusion-dependent Beta ThalassemiaCompletedNCT03947632
- Dermatological Abnormalities in Beta-thalassemia MajorStatus unknownNCT03894605
- Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to InsulinCompletedNCT03889977Not applicable
- Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent PatientsCompletedNCT03877809Phase 2
- Red Cell Distribution Width Index Versus Red Cell Distribution Width as Discriminating Guide for Iron Deficiency Anaemia and Beta Thalassemia Trait .Status unknownNCT03868306
- Zinc Supplementation in Patients With β-Thalassemia Major Complicated With Diabetes MellitusCompletedNCT03851055Phase 3
- Sexual Maturation in β-Thalassemia Major Patients in Assiut University HospitalStatus unknownNCT03847558
- Detection Of β-thalassemia Carriers In AssiutStatus unknownNCT03822585Not applicable
- Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic AnemiaCompletedNCT03802201Phase 2
- SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare AnemiasWithdrawnNCT03801889Phase 2
- the Efficacy and Safety of Sugammadex in Children 0-2 Years OldStatus unknownNCT03728543Phase 2/3
- iHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia MutationsStatus unknownNCT03728322Early Phase 1
- A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-ThalassemiaCompletedNCT03655678Phase 2/3
- Early Check: Expanded Screening in NewbornsActive, not recruitingNCT03655223