beta-Thalassemia: all 312 studies
Page 3 of 4. Open to participants first (73), then studies with results posted, then the rest; newest registration first within each.
- Pilot Study to Assess the Safety, PK and Iron Chelating Activity of DST-0509 (Deferasirox) in Thalassemia Patients Refractory to ChelationCompletedNCT03637556Phase 2
- Complications in Children With B- Thalassemia MajorStatus unknownNCT03462784
- L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary HypertensionStatus unknownNCT03402191Phase 4
- A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta ThalassemiaTerminatedNCT03381833Phase 2
- Quality of Life and Treatment Satisfaction in β-Thalassemia Patients Receiving DeferasiroxStatus unknownNCT03358498
- Periodontal Therapy in Thalassemia Major PatientsCompletedNCT03311243Not applicable
- Gene Transfer for Sickle Cell DiseaseActive, not recruitingNCT03282656Phase 1
- Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically ModifiedStatus unknownNCT03276455Phase 1/2
- Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)Active, not recruitingNCT03275051Not applicable
- A Study of Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-ThalassemiaCompletedNCT03271541Phase 2
- Thalassemia Treatment Based on the Stem Cell TechnologyStatus unknownNCT03222453Not applicable
- The Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi PakistanStatus unknownNCT03183375Phase 2
- Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia MajorStatus unknownNCT03171831Phase 4
- Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia PatientsCompletedNCT03170245
- Evaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children HospitalCompletedNCT03161899
- Erythrocyte Glutamine Level Relation to Pulmonary Hypertension Risk in Beta Thalassemia Major ChildrenCompletedNCT03133169
- Zinc Supplementation on Cellular Immunity in Thalassemia MajorCompletedNCT03117192Phase 4
- Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of ChimerismStatus unknownNCT03101423Not applicable
- Pneumococcal Vaccination for Splenectomised Thalassemia Major Patients in IndonesiaCompletedNCT03095326Phase 4
- Denosumab Versus Zoledronic Acid in Thalassemia-Induced OsteoporosisTerminatedNCT03040765Phase 3
- Sperm DNA Damage in β-thalassemia Major: Is There a Role for Antioxidants?Status unknownNCT03014882Phase 1/2
- In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)TerminatedNCT02986698Phase 1
- The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia MajorStatus unknownNCT02984475Phase 4
- A Study of EPEG in Beta Thalassemia PatientsCompletedNCT02950857Phase 1
- The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj HospitalCompletedNCT02904252
- Benefits of Nigella Sativa in Children With Beta Thalassemia MajorStatus unknownNCT02816957Early Phase 1
- Study of The Therapeutic Benefits of Al-hijamah in Children With Beta Thalassemia MajorStatus unknownNCT02761395Not applicable
- Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis CCompletedNCT02744560Not applicable
- Effect of Spirulina on Serum Hyaluronic Acid in Beta Thalassemic Children With Hepatitis CCompletedNCT02744547Not applicable
- Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis CCompletedNCT02744105Not applicable
- the Potential Immunomodulatory Effects of Spirulina on Thalassemic ChildrenCompletedNCT02674607Not applicable
- Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta ThalassemiaCompletedNCT02671695Not applicable
- Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene TherapyActive, not recruitingNCT02633943
- To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of CareCompletedNCT02626689
- Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia MajorCompletedNCT02597595Not applicable
- Denosumab vs Placebo in Patients With Thalassemia Major and OsteoporosisCompletedNCT02559648Phase 2
- Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia PatientsStatus unknownNCT02474420Not applicable
- Gene Therapy for Transfusion Dependent Beta-thalassemiaStatus unknownNCT02453477Phase 1/2
- B-Thalasaemia Trait and Its Possible Cardioprotective RoleStatus unknownNCT02428023
- Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia MajorCompletedNCT02342145Phase 4
- Reproductive Capacity and Iron Burden in ThalassemiaCompletedNCT02308904Not applicable
- Long Term Outcomes in β Thalassemia MajorCompletedNCT02307786
- Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-ThalassemiaTerminatedNCT02274233Phase 1
- Hepcidin Levels in Sickle Cell Disease (SCD)CompletedNCT02258997
- Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia PatientsCompletedNCT02198508Not applicable
- Hematopoietic Stem Cell Transplant for High Risk HemoglobinopathiesTerminatedNCT02179359Not applicable
- An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major PatientsStatus unknownNCT02173951Phase 2/3
- Unrelated Umbilical Cord Blood Following HLA-haploidentical Hematopoietic Stem Cell Transplantation in Patients With β-thalassemia MajorStatus unknownNCT02126046Not applicable
- MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent AnemiasCompletedNCT02090699
- Role of Vitamin C to Augment Iron Chelation With DFP or DFXStatus unknownNCT02083575Phase 2/3
- Efficacy and Safety of Efficacy and Safety of Continued Iron Chelation Therapy In Poly-transfused Thalassemia Patients With Low Serum Ferritin (< 500 ng/ml)Status unknownNCT01996683Not applicable
- A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.Status unknownNCT01935661
- At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsCompletedNCT01931644
- Treatment of Iron Overload Requiring Chelation TherapyWithdrawnNCT01927913Phase 2
- Bone Marrow Transplant With Abatacept for Non-Malignant DiseasesCompletedNCT01917708Phase 1
- B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic IndividualsStatus unknownNCT01846923Phase 4
- Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia MajorCompletedNCT01752153Phase 1
- Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC TransfusionCompletedNCT01740531Phase 3
- An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years OldWithdrawnNCT01724138Phase 4
- Trial of HQK-1001 in Beta Thalassemia Intermedia in LebanonCompletedNCT01642758Phase 2
- Therapeutic Effect and Safety of Combined Hydroxyurea With Recombinant Human Erythropoietin.Status unknownNCT01624038Phase 2/3
- Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in ThailandCompletedNCT01609595Phase 2
- Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E PatientsCompletedNCT01597765Not applicable
- Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron OverloadStatus unknownNCT01511848Phase 2/3
- Prevalence of Pulmonary Hypertension (PAH) in Patients With ThalassemiaCompletedNCT01496963
- Demographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia IntermediaCompletedNCT01443312
- Phase I/II Pilot Study of Mixed Chimerism to Treat HemoglobinopathiesWithdrawnNCT01419704Phase 1/2
- Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia MajorCompletedNCT01395199Phase 3
- The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response StudyStatus unknownNCT01323608Phase 4
- Beta-thalassemia and MicroparticlesCompletedNCT01284738Not applicable
- High-Tc Susceptometer to Monitor Transfusional Iron OverloadCompletedNCT01241357
- Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological DisordersCompletedNCT01224496Phase 1/2
- Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia MajorCompletedNCT01206075Not applicable
- GDF 15 in Sickle Cell Disease and Hereditary SpherocytosisStatus unknownNCT01201135
- Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TICompletedNCT01140321Phase 2
- Perceptions of Thalassemia Major in Singapore: An Exploratory Study of StigmaCompletedNCT01129076
- Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia MajorCompletedNCT01125254Phase 2/3
- Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-ThalassemiaStatus unknownNCT01092169
- CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor TransplantCompletedNCT01049854Phase 2
- Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron OverloadCompletedNCT01039636Phase 1
- Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major PatientsStatus unknownNCT01016093Phase 2/3
- Therapeutic Effects of Silymarin in Patients With B-thalassemia MajorStatus unknownNCT00999349Phase 2/3
- Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia IntermediaCompletedNCT00809042Phase 2
- Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia MajorCompletedNCT00800761Phase 4
- Phase 1/2 Study of HQK-1001 in Patients With Beta ThalassemiaCompletedNCT00790127Phase 1/2
- The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell TransplantationCompletedNCT00789516
- Efficacy Study of the Use of Sequential DFP-DFO Versus DFPCompletedNCT00733811Phase 4
- Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron OverloadCompletedNCT00564941Phase 4
- Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron OverloadCompletedNCT00560820Phase 1
- Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic CounterStatus unknownNCT00481221
- Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia MajorCompletedNCT00480506
- Endocrine and Nutritional Assessment in B Thalassemia MajorCompletedNCT00456690Not applicable
- Stem Cell Transplant in Sickle Cell Disease and ThalassemiaActive, not recruitingNCT00408447Phase 2
- Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia MajorCompletedNCT00336362Not applicable
- A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional HemosiderosisCompletedNCT00171171Phase 3
- Genetic Factors Affecting the Severity of Beta ThalassemiaCompletedNCT00159042
- Efficacy Study in Removing Excess Iron From the HeartCompletedNCT00105495Phase 4
- Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia MajorStatus unknownNCT00103753Phase 4
- Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-ThalassemiaCompletedNCT00069862Phase 1/2
- Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic AnemiasCompletedNCT00061763Phase 2