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Status unknownNCT03894605Updated Mar 28, 2019

Dermatological Abnormalities in Beta-thalassemia Major

An observational study in Beta-Thalassemia, sponsored by Assiut University. Status unknown. Open to participants aged 2 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-03-28.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Mar 2019), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
125
Ages
2 Years to 18 Years
Sex
All
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Study summary

to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion

Read the detailed description

thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years

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Conditions studied

  • Beta-Thalassemia

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In context

beta-Thalassemia

312 studies on the registry are indexed under beta-Thalassemia; 73 are open to participants now.

This study's planned enrollment of 125 is above the median of 100 across 84 observational studies indexed under beta-Thalassemia.

Browse beta-Thalassemia studies →

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
2 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

all patient examined by single dermatologist to record any dermatological abnormalities

Eligibility criteria

Inclusio2n Criteria:

  • clinical diagnosis of dermatological abnormalities in thalassemic patient. must be on chelator

Exclusion Criteria:

  • patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
125 participants (estimated)
Patient registry
No

Interventions

  • Devicethalassemia

    thalassemic patient use chelator and thaladssemic patient with frequent blood transfusion

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What researchers measure

Primary outcomes

  1. The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities

    the number of patients who develop any dermatological disorder as a result of iron overload after frequent blood transfusion

    Time frame: one month

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Cao A, Galanello R. Beta-thalassemia. Genet Med. 2010 Feb;12(2):61-76. doi: 10.1097/GIM.0b013e3181cd68ed. PubMed 20098328 ↗
  • El-Dash H, Adel S. Cutaneous manifestations in Egyptian children with beta-thalassemia major: Relationship with serum ferritin, thyroid profile, and treatment modalities. Pediatr Dermatol. 2018 Sep;35(5):639-643. doi: 10.1111/pde.13570. Epub 2018 Jun 26. PubMed 29943859 ↗
  • Dogramaci AC, Savas N, Ozer B, Duran N. Skin diseases in patients with beta-thalassemia major. Int J Dermatol. 2009 Oct;48(10):1057-61. doi: 10.1111/j.1365-4632.2009.04176.x. PubMed 19785086 ↗
  • CHANG PY, KUO CL, KHOO FY. The anatomic distribution of the lesions in pulmonary tuberculosis. Med Abstr. 1945 Oct;63A:237-43. No abstract available. PubMed 20997138 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 28, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03894605
Lead sponsor
Assiut University
Responsible party
Neveen Mamdoh Farag (Principal investigator, Assiut University) — Principal investigator
First posted
Mar 28, 2019
Start date
Mar 2, 2020 (estimated)
Primary completion
Mar 2, 2021 (estimated)
Completion
Apr 2, 2021 (estimated)
Last update
Mar 28, 2019

Study contacts

Alsayed khalil Abd elkareem, Professor
Contact
Khalilsay@gmail.com
01060805170
Mostafa Mohamed, Lecturer
Contact
Mustafa-embaby@aun.edu.eg
01006244311

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

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