A Phase 2 interventional study of Omega 3 Fish Oil supplements and Deferasirox in Thalassemia Majors (Beta-Thalassemia Major), sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to participants aged 6 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-10-07.
Sponsored by Ain Shams University · Phase 2, Interventional, and Treatment
the aim of this interventional study to show the effect of taking omega 3 for about 6 months for patients beta thalassemia major maintained on standard of care and receiving the iron chelator deferasirox on liver, cardiac functions and transfusion index the patients randomly distributed to two groups group A receiving the omega 3 in dose 1gram pr day(50 patients) group b not receiving the drug
312 studies on the registry are indexed under beta-Thalassemia; 73 are open to participants now.
This study's enrollment of 100 is above the median of 38 across 215 interventional studies indexed under beta-Thalassemia.
Browse beta-Thalassemia studies →Ain Shams University is the lead sponsor of 1,930 studies on the registry; 433 are open to participants now.
Of its 33 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
age: 6-18 years old children and adolescents with transfusion dependent thalassemia(TDT).diagnosis of TDT is based on clinical severity and transfsion requirements according to thalassemia international federation(TIF)guidelines
Exclusion Criteria:
beta thalassemia patients receiving the omega 3 supplementation and deferasirox
Drug: Omega 3 Fish Oil supplements · Drug: Deferasirox
50 patients beta thalassemia patients receiving standard of care and deferasirox
Drug: Deferasirox
beta thalassemia patients receiving standard of care receiving omega 3 supplemetaion and effect of this on liver and cardiac functions and transfuison index
beta thalassemia patients receiving standard of care and deferasirox and effect on liver and cardiac functions and transfusion index
Liver iron concentration
measure the iron content of liver by MRI imaging with no need for biopsy in milliseconds
Time frame: 6 months
transfusion index in ml/kg/year
the total amount of packed red blood cells transfused per kilogram of body weight per year
Time frame: 6 months
hemoglobin in g/dl
iron containing protein in red blood cells
Time frame: 6 months
serum ferritin in ng/ml
the iron store in body which reflect iron overload
Time frame: 6 months
lactate dehydrogenase(LDH) in U/L
marker of hemolysis increased in hemolysis
Time frame: 6 months
controlled attenuation parameter (CAP) in decibel per meter
it is a measurement of attenuation of ultrasound waves by liver fat used to estimate the amount of hepatic steatosis
Time frame: 6 months
ejection fraction
it is percentage of blood pumped out of ventricle during each heart beat compared with amount of blood present in ventricle before contraction
Time frame: 6 months
superoxide dismutase in units per mililiter(U/L)
it is antioxidant enzyme that converts superoxide radicals imto hydrogen peroxide and oxygen protecting cells from oxidative damage
Time frame: 6 months
Plan to share: No
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Fish Oils