Appendiceal Neoplasms: all 86 studies

Page 1 of 1. Open to participants first (25), then studies with results posted, then the rest; newest registration first within each.

• The Appendix Cancer PMP Research Foundation Natural History Study/Patient RegistryRecruitingNCT07769346
• Molecular Profiling for Risk Stratification in Appendiceal CancerRecruitingNCT07587268
• Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid TumorsRecruitingNCT07487168Phase 1
• A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal MetastasisRecruitingNCT07291180Not applicable
• Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment DelaysRecruitingNCT07283939Not applicable
• Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT TrialRecruitingNCT07271355Phase 3
• Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)RecruitingNCT07124351Phase 4
• NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal CancersRecruitingNCT07060014Phase 1
• A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsRecruitingNCT07020221Phase 1/2
• Target-specific immunoPET Imaging of Digestive System CarcinomaRecruitingNCT06715839Not applicable
• EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.RecruitingNCT06263088Not applicable
• Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsRecruitingNCT06128551Phase 1/2
• Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)RecruitingNCT06101277Not applicable
• Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the AppendixRecruitingNCT05919758
• Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)RecruitingNCT05913674Phase 2
• Individualized Dose Escalation of 5-FU for Gastrointestinal CancerRecruitingNCT05780684Not applicable
• Genetics of Appendix Cancer StudyRecruitingNCT05734430
• Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix CarcinomaRecruitingNCT05472948Phase 2
• Molecular Characterisation of Appendiceal CancerRecruitingNCT05364788
• Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesRecruitingNCT04907643Not applicable
• Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 1
• Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPECRecruitingNCT04779554Phase 2
• The Prevalence of Appendiceal Tumours in Periappendicular AbscessNot yet recruitingNCT04634448Not applicable
• PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
• Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal CarcinomatosisRecruitingNCT03073694Phase 2
• Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal CarcinomatosisCompletedNCT05185947Phase 2Results posted
• Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX ChemotherapyCompletedNCT04526886Not applicableResults posted
• Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal CancerCompletedNCT04505553Phase 2Results posted
• LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal CarcinomaTerminatedNCT03287947Phase 2Results posted
• A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal MalignanciesCompletedNCT02963831Phase 1/2Results posted
• Programs To Support You During ChemotherapyCompletedNCT02489422Not applicableResults posted
• HIPEC for Peritoneal CarcinomatosisCompletedNCT02040142Phase 2Results posted
• Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the AppendixCompletedNCT01580410Phase 2Results posted
• Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal CancerTerminatedNCT00903396Phase 2Results posted
• Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 3Results posted
• Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix CancerCompletedNCT00310076Phase 2Results posted
• Debulking and Chemotherapy With or Without Intraperitoneal Chemotherapy to Treat Peritoneal CarcinomatosisCompletedNCT00052962Phase 3Results posted
• Intraperitoneal LSTA1 in CRS-HIPECWithdrawnNCT06216561Phase 1
• Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal NeoplasmsActive, not recruitingNCT05623787Not applicable
• Severe Neutropenia After HIPEC Using Mitomycin-CCompletedNCT05513183
• Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsActive, not recruitingNCT05462717Phase 1
• Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)CompletedNCT05461430
• Surgical Outcome and Predictors of Overall Survival of Stage I-III Appendiceal AdenocarcinomaCompletedNCT05452382
• Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal MalignancyActive, not recruitingNCT05305820Not applicable
• Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal CancerActive, not recruitingNCT05277766Phase 1
• Justification of Incidental Appendectomy With Respect to Pathohistological FindingsStatus unknownNCT05202600
• JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C MutationActive, not recruitingNCT05194995Phase 1/2
• Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative ChemotherapyCompletedNCT05083338
• Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to DrugsWithdrawnNCT04985357
• Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid TumorsCompletedNCT04902872Phase 1/2
• Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal CancerTerminatedNCT04158349Phase 1
• Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal MetastasisActive, not recruitingNCT04157322
• The Registry of Oncology Outcomes Associated with Testing and TreatmentCompletedNCT04028479
• Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal CancersCompletedNCT03604653
• Selective Rather Than Routine Histopathological Examination Following Appendectomy and CholecystectomyCompletedNCT03510923
• PIPAC for Peritoneal Metastases of Colorectal CancerCompletedNCT03246321Phase 2
• International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)Status unknownNCT03210298
• Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRICompletedNCT02833753Phase 1
• Gastrointestinal Microbiome Study of Appendiceal CancerStatus unknownNCT02599116Not applicable
• Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal OriginActive, not recruitingNCT02387203Phase 2
• Knowledge, Attitudes, and Practice of Surgeons Toward Nutrition Support in HIPEC PatientsCompletedNCT02374411
• Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma PeritoneiActive, not recruitingNCT01946854Not applicable
• ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal MetastasisActive, not recruitingNCT01815359Phase 2
• Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)CompletedNCT01126346Not applicable
• Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal CancerCompletedNCT00654160Phase 1
• Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal CancerCompletedNCT00458809Phase 1
• Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal CancerCompletedNCT00397384Phase 1
• Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal CancerStatus unknownNCT00274885Phase 4
• Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer PatientsCompletedNCT00253383Not applicable
• Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal ChemohyperthermiaTerminatedNCT00180960Phase 2
• Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver CancerCompletedNCT00096083Phase 2
• EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerTerminatedNCT00087191Not applicable
• PV701 in Treating Patients With Advanced or Recurrent Peritoneal CancerCompletedNCT00055705Phase 1
• Thalidomide and Docetaxel in Treating Patients With Advanced CancerCompletedNCT00049296Phase 1
• 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)CompletedNCT00031681Phase 1
• MS-275 in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT00020579Phase 1
• Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel CancerCompletedNCT00019773Phase 1
• Ondansetron With/Out Dexamethasone to Prevent Vomiting in Patients Receiving Radiation to the Upper AbdomenCompletedNCT00016380Phase 3
• Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT00010023Phase 1
• Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal CancerStatus unknownNCT00006112Phase 2
• Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the PeritoneumCompletedNCT00005860Phase 1
• Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic CancerCompletedNCT00005842Phase 1
• Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/NeuCompletedNCT00004074Phase 1
• Irinotecan and Capecitabine in Treating Patients With Solid TumorsCompletedNCT00003867Phase 1
• Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal CavityCompletedNCT00003548Phase 1
• Interleukin-12 in Treating Patients With Cancer in the AbdomenCompletedNCT00003046Phase 1

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