Amenorrhea clinical trials
The registry lists 79 studies for Amenorrhea across more than 10 countries. 16 are recruiting or about to start. 47 of them are mainly about Amenorrhea (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Massachusetts General Hospital (8) · National Institute of Environmental Health Sciences (NIEHS) (4) · Cornell University (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (3) · Karolinska Institutet (2) · Bayer (2) · Penn State University (2) · Duramed Research (2)
What is being tested here
Drugs under test in Amenorrhea studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Mibavademab | 1 | 0 | 1 |
| Progesterone | 0 | 1 | 4 |
| Estradiol | 0 | 1 | 3 |
| Metformin | 0 | 0 | 3 |
| Inositol | 0 | 0 | 2 |
| Telapristone acetate | 0 | 0 | 2 |
| Asoprisnil | 0 | 0 | 2 |
| Gonadotropin-Releasing Hormone | 0 | 0 | 2 |
| Chiro-inositol, (+)- | 0 | 0 | 1 |
| Flutamide | 0 | 0 | 1 |
Drug classes tested here Estrogens 5 · Antiandrogens 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Jan 2027Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women · Phase 3 · Genesis Athens Clinic
- Dec 2026Menstrual Cycle Maintenance and Quality of Life: A Prospective Study · Memorial Sloan Kettering Cancer Center
- Dec 2026Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH) · Mayo Clinic
- Jul 2027Feasibility of a Digital Self-help Program for Functional Hypothalamic Amenorrhea (HEAL-FHA Pilot) · Karolinska Institutet
Who these studies take
Of the 13 Amenorrhea studies recruiting now, 0 (0%) set no upper age limit and 11 (85%) stop at 75 or younger. 8 (62%) take children under 18. 11 (85%) are for women only and 0 (0%) for men only; 3 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (23%) | 2 (15%) |
| 18 | 10 (77%) | 2 (15%) |
| 30 | 11 (85%) | 2 (15%) |
| 40 | 5 (38%) | 2 (15%) |
| 50 | 3 (23%) | 2 (15%) |
| 65 | 2 (15%) | 2 (15%) |
| 75 | 2 (15%) | 2 (15%) |
| 85 | 2 (15%) | 2 (15%) |
Across all 79 studies, recruiting or not: 86% stop at 75 or younger and 86% at 65; 34% take children; 94% are for women only and 0% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 79. Browse all 79 → or search them.
- Feasibility of a Digital Self-help Program for Functional Hypothalamic Amenorrhea (HEAL-FHA Pilot)RecruitingNCT07589868Not applicable1 country
- A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic AmenorrheaRecruitingNCT07235917Phase 21 country
- Inherited Reproductive DisordersRecruitingNCT015004471 country
- Observation of Environment and Reproductive-Endocrine EffectsRecruitingNCT062808071 country
- Role of Estrogen on Skeletal Outcomes in FHARecruitingNCT07010146Phase 21 country
- Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal WomenRecruitingNCT03916978Phase 2/31 country
- Effects of Resistance Training on Women With Functional Hypothalamic AmenorrheaNot yet recruitingNCT07612735Not applicable1 country
- The Research of Integrated Traditional Chinese and Western Medicine on Hypothalamic AmenorrheaRecruitingNCT07580950Phase 41 country
- Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic AmenorrheaRecruitingNCT06533865Phase 31 country
- Health and Lifestyle Support for Functional Hypothalamic AmenorrheaNot yet recruitingNCT07386223Not applicable1 country
- Effects of Physical and Psychosocial Stress on Functional Hypothalamic Amenorrhea in Exercising WomenRecruitingNCT05967819Not applicable1 country
- Metabolism, Circadian Rhythms and Ovarian FunctionRecruitingNCT050078341 country
- Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With AmenorrheaRecruitingNCT070154761 country
- Ovarian Morphology in GirlsRecruitingNCT044245761 country
- AMH and Functional Hypothalamic AmenorrheaRecruitingNCT059218771 country
- Hormonal Status, Performance and Health in Elite Female AthleteNot yet recruitingNCT05028959Not applicable
- The Role of Estrogen in the Neurobiology of Eating DisordersCompletedNCT03740204Phase 21 country
- Hormonal Regulation of Puberty and FertilityCompletedNCT015115881 country
- Treatment of Menstrual Cycle Alterations in AdolescentsCompletedNCT06800170Not applicable2 countries
- NAFLD in Adolescents and Young Adults With PCOSSuspendedNCT025069461 country
- Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian SyndromeCompletedNCT07701525Phase 41 country
- Menstrual Cycle Maintenance and Quality of Life: A Prospective StudyActive, not recruitingNCT005896541 country
- Effects of Dietary Nitrate in Women With Secondary AmenorrheaTerminatedNCT07019129Not applicable1 country
- Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH)Active, not recruitingNCT056293771 country
- A Study to Measure Pharmacokinetic (PK) Concentrations of Gonadotropin-Releasing Hormone Delivered by the OmniPod PumpWithdrawnNCT07152730Phase 11 country
- Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic PracticeCompletedNCT071642481 country
- Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)TerminatedNCT02500147Phase 41 country
- Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young WomenCompletedNCT03018366Phase 21 country
- Retrospective Study of Surgical Induced Abortions Between 14 and 16 Weeks of Amenorrhea At Croix Rousse University Hospital in LyonCompletedNCT068716181 country
- Evaluation of Ovarian Morphology and Function in Overweight Women During Weight LossCompletedNCT01785719Not applicable1 country
- Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS WomenCompletedNCT01889199Phase 21 country
- Compliance and EndometriosisCompletedNCT056197571 country
- Screening Women for Functional Hypothalamic Amenorrhea (FHA)CompletedNCT054108861 country
- Ultrasound Characterization of Ovarian Follicle Dynamics in Women With AmenorrheaCompletedNCT019274321 country
- Isolated Growth Hormone Deficiency and AmennorrheaCompletedNCT054489241 country
- The Effect of Polycystic Ovary Syndrome Treatment on MetabolomicsStatus unknownNCT04831151Not applicable1 country
- Effects of Anorexia Nervosa on Bone Mass in AdolescentsCompletedNCT00088153Phase 2/31 country
- Bone Mass Accrual in Adolescent AthletesWithdrawnNCT00827151Phase 31 country
- Rejuvenation of Premature Ovarian Failure With Stem CellsCompletedNCT02696889Not applicable1 country
- Reproductive Health Outcomes by Method of Breast Milk FeedingCompletedNCT035688511 country
- Bioenergetics of Exercise-Induced Menstrual DisturbancesCompletedNCT04938622Not applicable
- Fat Mediated Modulation of Reproductive and Endocrine Function in Young AthletesCompletedNCT00946192Phase 31 country
- KYleena Satisfaction Study / Observational Study on User Satisfaction With the Levonorgestrel Intrauterine Delivery System Kyleena (LNG-IUS 12) in New Contraceptive Users and After Switching From Another Contraceptive MethodCompletedNCT031821408 countries
- LutrePulse Hypogonadotropic HypogonadismCompletedNCT01976728Phase 32 countries
- Psychological Impact of Amenorrhea in Women With EndometriosisStatus unknownNCT02393482Phase 41 country
- Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic AmenorrheaCompletedNCT005560361 country
- Mental Health in Fitness InstructorsCompletedNCT041357291 country
- TDM of Gentamicin and Vancomycin, in Neonates, Using Dried Blood Spot Sampling.Status unknownNCT036511151 country
- Estradiol and Fear Extinction in Anorexia Nervosa (AN)WithdrawnNCT02792153Phase 11 country
- A Phase 3, Randomized, Three-Cycle, Double-Blind, Placebo-Controlled Study to Evaluate Induction of Secretory Conversion of Endometrium and Withdrawal Bleeding for Secondary AmenorrheaTerminatedNCT02019589Phase 31 country