ClinicalTrials.gg
RecruitingNCT07935473OBEXSNACKUpdated Nov 13, 2026

Effects of "Exercise Snack" in Individuals With Obesity

An interventional study of Exercise snack and Conventional exercise training in Obesity & Overweight and Obesity / Overweight, sponsored by Istituto Auxologico Italiano. Recruiting at 1 site in Italy. Open to participants aged 30 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-13.

Sponsored by Istituto Auxologico Italiano · Not applicable, Interventional, and Treatment

Updated Nov 13, 2026Newly registeredGo to Updates ↓

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Phase
Not applicable
Study type
Interventional
Enrollment
8
Allocation
Randomized
Ages
30 Years to 70 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-14

Among 42 studies in Obesity by Istituto Auxologico Italiano — 11 open to participants now, 12 under way, none of them phase 3. Obesity · Istituto Auxologico Italiano.

Planned enrollment
20th of 22
8 · median 32
Started
2026
the only one that year
No phase
20 of 42
6 open now
Primary completion
2027-02
later than 11 of 11 live
Registered
42nd of 42
by date

Among the 42 studies in Obesity by Istituto Auxologico Italiano, this one is the 20th largest by planned enrollment of the 22 interventional ones that give a count, is the only one that started in 2026, is one of 20 with no phase, reaches primary completion later than 11 of the 11 other live ones, and was the 42nd registered.

Obesity

11,536 studies on the registry are indexed under Obesity; 2,042 are open to participants now.

Browse Obesity studies →

Open to participants now

11 of the 42 studies in Obesity by Istituto Auxologico Italiano are open now, in 1 country. Recruiting first, the newest first:

5 more — sign in →

By country, each count listing its studies:

All 11 open studies →

Where they have run

Who these studies take

Of the 1,339 Obesity studies recruiting now, 377 (28%) set no upper age limit and 859 (64%) stop at 75 or younger; 167 take children under 18; 490 take healthy volunteers.

This study: 30 Years to 70 Years · all sexes · healthy volunteers too.

The full table on the hub →

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 42 studies in Obesity by Istituto Auxologico Italiano, or all of them as a file.
02

Study summary

Obesity is associated with reduced physical fitness, functional limitations, and poorer quality of life (Kell et al., 2001). Nutritional support and supervised exercise can improve weight management and physical health, but low motivation and perceived lack of time often limit participation to physical activity (Alberga et al., 2013; Baillot et al., 2021). Evidence shows that shorter-time exercise strategies may help overcome these barriers and support training adherence (Poon et al., 2020). Brief activity bouts distributed throughout the day, including vigorous intermittent lifestyle physical activity and structured "exercise snacks," may help to improve cardiorespiratory fitness, muscle function, and metabolic health (Islam et al., 2022; Ahmadi et al., 2024; Wang et al., 2024). Observational evidence also links VILPA to lower mortality risk (Stamatakis et al., 2023). Combining brief exercise bouts with education to interrupt prolonged sitting may therefore address both insufficient physical activity and sedentary behaviour (Dunstan et al., 2021; Dogra et al., 2022; Pinto et al., 2023). Generally, research has largely focused on healthy, inactive adults, with limited evidence in people with overweight or obesity (Jones et al., 2024). Rafiei et al. (2021) reported acute improvements in insulin and non-esterified fatty acid responses following brief stair-climbing bouts compared with prolonged sitting in adults with obesity. Schmidt et al. (2001) found comparable improvements in body composition and aerobic fitness following accumulated or continuous exercise during caloric restriction. The effects of exercise snacks combined with education to reduce sedentary behaviour nevertheless remain unclear. This study aims to evaluate the effects of an exercise-snacking programme on body composition, physical fitness, quality of life, and exercise adherence in adults with obesity.

03

Conditions studied

  • Obesity & Overweight
  • Obesity / Overweight
04

Who can participate

Ages eligible
30 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Male or female gender
  • more than 30 kg/m2
  • Participation in physical activity fewer than twice per week
  • signature

Exclusion criteria

Exclusion Criteria:

  • aged more than 70 years
  • history of disabling musculoskeletal or osteoarticular conditions that prevent regular participation in physical activity, with a pain score > of 7 out of 10 arbitrary units on the visual analogue scale (VAS)
  • history of hip or knee replacement
  • Surgery within the 6 months preceding the study
  • presence of severe hip or knee osteoarthrosis
  • presence of cardiac, neurological or psychiatric disordes
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
8 participants (estimated)

Study arms

  • Experimental
    Exercise Snack Group

    Exercise snacks activity throughout the day

    Other: Exercise snack

  • Experimental
    Traditional Fitness Group

    Conventional circuit training exercise

    Other: Conventional exercise training

Interventions

  • OtherExercise snack

    10-week-home-based training protocol to improve cardiorespiratory fitness, muscular strength and stability performed through a short bout of physical activity called "exercise snack". The programme consists of high-intensity home-based exercises performed in five 2-minute bouts per day, spaced 2 hours apart, for 7 days (10 minutes of exercise per day).

  • OtherConventional exercise training

    10-week-home-based training protocol to improve cardiorespiratory fitness, muscular strength and stability performed through a circuit-training mode. The programme consists of home-based exercises performed in a circuit-training format (time of work per set 20 s, time of rest between each exercise 10 s, time of rest between sets 2 min, total volume 3 sets) for a duration of 35 min with a frequency of 3 days per week while performing traditional strength and postural control exercises.

06

What researchers measure

Primary outcomes

  1. Change from baseline fat mass at ten weeks

    Fat mass percentage measurement using a bioelectric impedance analysis

    Time frame: up to ten weeks

  2. Change from baseline fat free mass at ten weeks

    Fat free mass percentage measurement using a bioelectric impedance analysis

    Time frame: up to ten weeks

  3. Change from baseline waist circumference at ten weeks

    Waist circumference using a 200 centimeters tape measure in centimeters

    Time frame: up to ten weeks

  4. Change from baseline weight at ten weeks

    Body weight using a calibrated weight scale in kilograms

    Time frame: up to ten weeks

Secondary outcomes

  1. Change from baseline body balance at ten weeks

    Body stability using the modified version of the Balance Error Scoring System protocol in arbitrary units with a 0-30 point scale in which lower scores mean a better outcome

    Time frame: up to ten weeks

  2. Change from baseline upper-body muscular strength at ten weeks

    Maximal isometric grip strength in kilograms using the handgrip dynamometer

    Time frame: up to ten weeks

  3. Change from baseline lower-body muscular strength at six weeks

    Amount of time in seconds during a chair raise using the Five Repetition Sit-To-Stand protocol

    Time frame: up to ten weeks

  4. Change from baseline cardiorespiratory fitness at ten weeks

    Heart rate monitor in beats per minute during a 45-second squat exercise using the Ruffier-Dickson squat test protocol

    Time frame: up to ten weeks

  5. Change from baseline amount of physical activity at ten weeks

    Weekly amount of physical activity and sedentary time using the short-form International Physical Activity Questionnaire expressed in mets per week

    Time frame: up to ten weeks

  6. Change from baseline enjoyment at ten weeks

    Exercise enjoyment using the short-form PACES scale questionnaire in arbitrary units with a 0-5 point scale in which higher scores mean a better outcome

    Time frame: up to ten weeks

  7. Change from baseline adherence at ten weeks

    Exercise enjoyment using the Exercise Adherence Rating Scale questionnaire in arbitrary units with a 0-5 point scale in which higher scores mean a better outcome

    Time frame: up to ten weeks

  8. Change from baseline quality of life perception at ten weeks

    Subjective quality of life perception using the using the EuroQol EQ-5D VAS in arbitrary units with a 0-100 point scale in which higher scores mean a better outcome

    Time frame: up to ten weeks

07

Study locations

1 of 1 sites recruiting
08

References and documents

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Nov 2026 (actual). Primary completion is estimated for Feb 2027, 3 months after the start.

Of 3,685 non-industry interventional studies with no phase under Obesity, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 43. This study's planned 3 months is below that.

Counting every sponsor, half of 3,848 studies reached it within 22 months; a quarter within 9 and three quarters within 42.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 9, 2026
First posted
Nov 13, 2026
StartActual
Nov 1, 2026
Primary completionEst.
Feb 25, 2027
CompletionEst.
Mar 31, 2027
Last update
Nov 13, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 13, 2026
Show all 1 update
  1. Nov 13, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07935473
Responsible party
Sponsor
First posted
Nov 13, 2026
Start date
Nov 1, 2026
Primary completion
Feb 25, 2027 (estimated)
Completion
Mar 31, 2027 (estimated)
Last update
Nov 13, 2026

Study contacts

Luca Cavaggioni, PhD
Contact
cavaggioni.luca@gmail.com
+3902619111
Luca Cavaggioni, PhD
principal investigator · Istituto Auxologico Italiano IRCCS

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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