An interventional study of Moderate-Intensity Cycling Under Fasted and Fed Conditions in Metabolism Changes, Exercise and Energy Metabolism, sponsored by Hacettepe University. Completed at 1 site in Turkey (Türkiye). Open to male participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Hacettepe University · Not applicable, Interventional, and Basic science
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Among 101 studies in Motor Activity by Hacettepe University — 24 open to participants now, 24 under way, none of them phase 3. Motor Activity · Hacettepe University.
Among the 101 studies in Motor Activity by Hacettepe University, this one is the 68th largest by enrollment of the 71 interventional ones that give a count, is one of 9 that started in 2026, is one of 70 with no phase, and was the 100th registered.
9,812 studies on the registry are indexed under Motor Activity; 1,917 are open to participants now.
Browse Motor Activity studies →24 of the 101 studies in Motor Activity by Hacettepe University are open now, in 1 country. Recruiting first, the newest first:
Hacettepe University · Sites in Turkey
Ages 18+ · Men only
Hacettepe University · Sites in Turkey
Ages 30–45 · Healthy volunteers
Hacettepe University · Sites in Turkey
Ages 18+ · Healthy volunteers
Hacettepe University · Sites in Turkey
Ages 7+
Hacettepe University · Sites in Turkey
Ages 40+ · Healthy volunteers
By country, each count listing its studies:
Of the 1,204 Motor Activity studies recruiting now, 518 (43%) set no upper age limit and 538 (45%) stop at 75 or younger; 180 take children under 18; 421 take healthy volunteers.
This study: 18 Years to 35 Years · male · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
101 studies; the count open now beside each. This study's row is marked.
First in 2002; this study’s year is marked. 9 started in 2026.
This study's enrollment of 11 is below the median of 60 across 8,399 interventional studies indexed under Motor Activity.
Median enrollment 36 across the 71 interventional studies, 52 across the 30 observational. Of the 61 that completed or were terminated, 2 (3%) have results posted.
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Hacettepe University is the lead sponsor of 1,009 studies on the registry; 214 are open to participants now.
7 of the studies in Motor Activity by Hacettepe University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07681427Hacettepe UniversityEffects of a 12-week T10 Exercise Program on Shooting Performance, Upper Extremity Function, Balance and Reaction Time in Competitive Air Pistol Athletes | 2026-11-15 |
| NCT07229963Hacettepe UniversityExercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults | 2026-11-20 |
| NCT07401056Hacettepe UniversityPreoperative Structured Exercise Programme on Patients With Non-Small Cell Lung Cancer | 2027-02 |
| NCT07369609Hacettepe UniversityFactors Influencing Physical Activity Levels in Children With Duchenne Muscular Dystrophy: An ICF-CY-Based Study | 2027-02-02 |
| NCT07930221Hacettepe UniversityThe Effects of Yoga Practice on Exercise Capacity, Arterial Stiffness, Respiratory Function, Peripheral Muscle Strength, Posture and Quality of Life in Children With Cystic Fibrosis | 2027-07 |
Add all 7 to your calendar (.ics) → With an account.
Among the 101 studies in Motor Activity by Hacettepe University, from their registry updates:
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The goal of this study was to determine whether eating before exercise changes how male soccer players use fat and carbohydrate for energy. This study also examined how consistent these measurements are when the same exercise test was repeated on separate days. The main questions it aimed to answer were:
Were measurements of fat and carbohydrate use during exercise consistent across two tests performed after an overnight fast?
Did fat and carbohydrate use during exercise differ between fasted and fed conditions?
Participants attended the laboratory on four occasions after fasting overnight for 10-12 hours, had their body composition and maximal aerobic fitness measured, and completed a practice cycling session during the first visit.
During the second and third visits, all participants completed a 30-minute cycling test at a moderate intensity following overnight fasting to establish the test-retest reproducibility of metabolic measurements.
During the fourth visit, they completed two 30-minute cycling tests: one before eating and another one hour after an unrestricted meal of pasta and meatballs. During cycling test, participants wore a mask so researchers could measure their breathing gases and estimate how much fat and carbohydrate they used for energy.
This study was designed to investigate the reproducibility of exercise substrate oxidation measurements and to compare metabolic responses to moderate-intensity exercise under fasted and fed conditions in trained male soccer players. A repeated-measures, within-participant design was employed, incorporating separate test-retest assessments and a fixed-sequence comparison of fasting and feeding conditions. The study was conducted during the off-season to minimize potential variations in training load and competitive match demands.
Participants attended the laboratory on four separate occasions under standardized experimental conditions. All visits were scheduled at the same time of day following a 10-12-hour overnight fast to minimize potential circadian and nutritional influences on metabolic responses. Participants were instructed to avoid strenuous exercise, alcohol, and caffeine for at least 24 hours before each visit and to maintain comparable dietary intake before experimental trials.
During the first laboratory visit, body composition was assessed using dual-energy X-ray absorptiometry (DXA), followed by a maximal incremental cycling test to determine maximal oxygen uptake (VO2max). Following a two-hour recovery period, participants completed a 20-minute familiarization session at 60% of VO2max to become accustomed to the experimental exercise protocol.
The second and third laboratory visits consisted of identical 30-minute submaximal cycling trials performed at 60% of VO2max under overnight-fasted conditions. These sessions were conducted to establish the test-retest reproducibility of metabolic measurements before the main experimental comparison.
During the fourth visit, conducted at least 72 hours after the preceding trial, participants completed two 30-minute cycling bouts at the same relative exercise intensity. The first bout was performed following an overnight fast. One hour after completing this bout, participants consumed an ad libitum meal consisting of pasta and meatballs. A second cycling bout was performed one hour after meal consumption, corresponding to two hours after completion of the initial exercise bout. The order of conditions was fixed, with the fasted trial always preceding the fed trial.
Respiratory gas exchange was continuously monitored during the submaximal exercise trials using an automated metabolic measurement system. Measurements obtained during predefined exercise intervals were used to characterize metabolic responses and evaluate the influence of feeding status during moderate-intensity exercise.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
All participants completed the same protocol. Following baseline assessments and familiarization, participants performed two 30-minute cycling tests at 60% of maximal oxygen uptake on separate days after a 10-12-hour overnight fast to assess test-retest reproducibility. During the final visit, participants completed a 30-minute cycling test at the same intensity after an overnight fast. One hour after completing this bout, they consumed an ad libitum meal of pasta and meatballs. One hour after meal ingestion, they completed a second 30-minute cycling test at the same intensity. Respiratory gases were measured during all cycling tests to calculate fat and carbohydrate oxidation rates.
Other: Moderate-Intensity Cycling Under Fasted and Fed Conditions
Participants completed 30 minutes of cycling on an electronically braked cycle ergometer at a workload corresponding to 60% of maximal oxygen uptake after a 10-12-hour overnight fast. One hour after completing the fasted exercise bout, participants consumed an ad libitum meal consisting of pasta and meatballs. One hour after meal ingestion, they completed a second 30-minute cycling bout at the same workload under fed conditions. Both bouts were performed during the same laboratory visit in a fixed sequence, with fasted exercise preceding fed exercise. Respiratory gases were measured during both bouts, and data from minutes 10-15 and 25-30 were used to calculate fat and carbohydrate oxidation rates.
Fat Oxidation Rate During Fasted and Fed Exercise
Fat oxidation rate (g/min) was calculated from oxygen uptake and carbon dioxide production measured by indirect calorimetry during cycling at 60% of V̇O₂max. Rates were calculated for two predefined periods, minutes 10-15 and 25-30, and compared between fasted and fed conditions.
Time frame: At 10-15 and 25-30 minutes after the start of each 30-minute cycling bout performed under fasted and fed conditions at Visit 4.
Carbohydrate Oxidation Rate During Fasted and Fed Exercise
Carbohydrate oxidation rate (g/min) was calculated from oxygen uptake and carbon dioxide production measured by indirect calorimetry during cycling at 60% of V̇O₂max. Rates were calculated for two predefined periods, minutes 10-15 and 25-30, and compared between fasted and fed conditions.
Time frame: At 10-15 and 25-30 minutes after the start of each 30-minute cycling bout performed under fasted and fed conditions at Visit 4.
Energy Expenditure During Fasted and Fed Exercise
Energy expenditure was calculated from oxygen uptake and carbon dioxide production measured by indirect calorimetry during cycling at 60% of V̇O₂max. Rates were calculated for two predefined periods, minutes 10-15 and 25-30, and compared between fasted and fed conditions.
Time frame: At 10-15 and 25-30 minutes after the start of each 30-minute cycling bout performed under fasted and fed conditions at Visit 4.
Respiratory Exchange Ratio During Fasted and Fed Exercise
Respiratory exchange ratio (RER) was calculated as the ratio of carbon dioxide production (V̇CO₂) to oxygen uptake (V̇O₂), measured by indirect calorimetry during cycling at 60% of V̇O₂max. Mean RER values were calculated for minutes 10-15 and 25-30 of each exercise bout and compared between fasted and fed conditions.
Time frame: At 10-15 and 25-30 minutes after the start of each 30-minute cycling bout performed under fasted and fed conditions at Visit 4.
Heart Rate During Exercise
Heart rate, expressed in beats per minute (bpm), was assessed during 30-minute cycling bouts at 60% of maximal oxygen uptake under fasted and fed conditions. Heart rate responses were compared between nutritional conditions and across exercise time points.
Time frame: At 10-15 and 25-30 minutes after the start of each 30-minute cycling bout performed under fasted and fed conditions at Visit 4.
Test-Retest Reproducibility of Fat Oxidation Rate During Submaximal Exercise
Fat oxidation rate (g/min) was calculated from respiratory gas exchange measurements obtained using indirect calorimetry during two identical 30-minute cycling trials at 60% of V̇O₂max under overnight-fasted conditions. Reproducibility between trials was evaluated using the intraclass correlation coefficient (ICC), coefficient of variation (CV%), standard error of measurement (SEM), and smallest detectable change at the 95% confidence level (SDC95).
Time frame: 10-15 and 25-30 minutes after the onset of each 30-minute cycling trial performed at 60% of V̇O₂max under overnight-fasted conditions at Visits 2 and 3 (test and retest, respectively).
Test-Retest Reproducibility of Carbohydrate Oxidation Rate During Submaximal Exercise
Carbohydrate oxidation rate (g/min) was calculated from respiratory gas exchange measurements obtained using indirect calorimetry during two identical 30-minute cycling trials at 60% of V̇O₂max under overnight-fasted conditions. Reproducibility between trials was evaluated using the intraclass correlation coefficient (ICC), coefficient of variation (CV%), standard error of measurement (SEM), and smallest detectable change at the 95% confidence level (SDC95).
Time frame: 10-15 and 25-30 minutes after the onset of each 30-minute cycling trial performed at 60% of V̇O₂max under overnight-fasted conditions at Visits 2 and 3 (test and retest, respectively).
Test-Retest Reproducibility of Respiratory Exchange Ratio During Submaximal Exercise
Respiratory exchange ratio (RER; dimensionless) was determined from the ratio of carbon dioxide production to oxygen uptake measured using indirect calorimetry during two identical 30-minute cycling trials at 60% of V̇O₂max under overnight-fasted conditions. Reproducibility between trials was evaluated using the intraclass correlation coefficient (ICC), coefficient of variation (CV%), standard error of measurement (SEM), and smallest detectable change at the 95% confidence level (SDC95).
Time frame: 10-15 and 25-30 minutes after the onset of each 30-minute cycling trial performed at 60% of V̇O₂max under overnight-fasted conditions at Visits 2 and 3 (test and retest, respectively).
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Feb 2026 to primary completion in Jul 2026, 5 months.
Of 5,158 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 5 months is below that.
Counting every sponsor, half of 5,218 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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