An interventional study of aerobic exercises + yoga and aerobic exercises in Cystic Fibrosis (CF), sponsored by Hacettepe University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 8 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Hacettepe University · Not applicable, Interventional, and Treatment
Among 16 studies in Cystic Fibrosis by Hacettepe University — 2 open to participants now, 2 under way, none of them phase 3. Cystic Fibrosis · Hacettepe University.
Among the 16 studies in Cystic Fibrosis by Hacettepe University, this one is the only one that started in 2025, is one of 4 with no phase, and was the 16th registered.
1,621 studies on the registry are indexed under Cystic Fibrosis; 201 are open to participants now.
Browse Cystic Fibrosis studies →2 of the 16 studies in Cystic Fibrosis by Hacettepe University are open now, in 1 country. Recruiting first, the newest first:
Hacettepe University · Sites in Turkey
Ages 18–45 · Healthy volunteers
By country, each count listing its studies:
Of the 156 Cystic Fibrosis studies recruiting now, 95 (61%) set no upper age limit and 45 (29%) stop at 75 or younger; 86 take children under 18; 41 take healthy volunteers.
This study: 8 Years to 18 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
16 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 1 started in 2025.
This study's planned enrollment of 36 is close to the median of 36 across 1,053 interventional studies indexed under Cystic Fibrosis.
Median enrollment 33 across the 4 interventional studies, 49 across the 12 observational. Of the 12 that completed or were terminated, 0 (0%) have results posted.
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Hacettepe University is the lead sponsor of 1,009 studies on the registry; 214 are open to participants now.
1 of the studies in Cystic Fibrosis by Hacettepe University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07930221Hacettepe UniversityThe Effects of Yoga Practice on Exercise Capacity, Arterial Stiffness, Respiratory Function, Peripheral Muscle Strength, Posture and Quality of Life in Children With Cystic Fibrosis | 2027-07 |
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Among the 16 studies in Cystic Fibrosis by Hacettepe University, from their registry updates:
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The aim of this study is to investigate the effects of exercise training applied through telerehabilitation on exercise capacity, peripheral and respiratory muscle strength, arterial stiffness, posture and quality of life in children with cystic fibrosis.
The most common problems in patients with cystic fibrosis (CF) are increased bronchial secretions, reduced exercise tolerance and shortness of breath.
Exercise capacity is limited due to muscle dysfunction, inflammation and progressive respiratory disease. Cardiovascular complications are one of the long-term complications of CF. Increased arterial stiffness is an indicator of elevated cardiovascular risk. It has been shown that patients with CF have increased arterial stiffness compared to their healthy peers.
Exercise training has a positive effect on exercise capacity, respiratory function and quality of life in patients with CF. Studies have shown that exercise training applied using the telerehabilitation method increases exercise capacity and improves peripheral muscle function in patients with CF. Peripheral muscle function, functional capacity, arterial stiffness and posture have been assessed in patients with CF. Furthermore, studies have been performed on patients with CF involving exercise training via telerehabilitation.In addition, various studies have shown that yoga and aerobic exercise training have positive effects on arterial stiffness. Although there are only a few studies involving patients with CF who practise yoga, no study has been found that assesses the effects of yoga practise via telerehabilitation on exercise capacity, peripheral and respiratory muscle function, and arterial stiffness.The purpose of this study is to examine the effects of exercise training using telerehabilitation on exercise capacity, peripheral and respiratory muscle strength, arterial stiffness, posture and quality of life in children with CF.
Children were randomly assigned to three groups: The first group will receive online aerobic exercise training and yoga sessions. The second group will receive only aerobic exercise training.The third group will be informed about the importance of physical activity and will be given recommendations for physical activity. Participants' respiratory function, exercise capacity, arterial stiffness parameters, peripheral muscle function, posture and quality of life questionnaire will be evaluated initially and following an 8-week exercise programme.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
From a breathing test (spirometry): how much air you can blow out in the first second. Often given as a percentage of what is expected for your age, height and sex.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
FEV1
From a breathing test (spirometry): how much air you can blow out in the first second. Often given as a percentage of what is expected for your age, height and sex.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
aerobic exercise training and yoga sessions in patients with cystic fibrosis
Other: aerobic exercises + yoga
only aerobic exercises in patients with cystic fibrosis
Other: aerobic exercises
physical activity recommendations in patients with cystic fibrosis
Other: Physical activity recommendations
Patients will be performed online in groups of 3-4 participants supervised aerobic exercises and yoga sessions. Aerobic exercises will be applied for 8 weeks, for 30-45 minutes, at 65-75% of the maximum heart rate, 3 days a week, on the days when yoga sessions are not performed. The yoga sessions will consist of 30-40-minute sessions, with three sessions per week for eight weeks. The yoga sessions will consist of three core components - asana (postures), pranayama (breathing) and meditation (focus).
Patients will be performed online in groups of 3-4 participants supervised only aerobic exercises Aerobic exercises will be applied for 8 weeks, for 30-45 minutes, at 65-75% of the maximum heart rate, 3 days a week.
Patients will be informed of the benefits of physical activity and appropriate physical activity recommendations will be provided.
six minute walk test
the distance reached in the six-minute walk test
Time frame: before the exercise training
six minute walk test
the distance reached in the six-minute walk test
Time frame: eigth week
Arterial stiffness
Arterial stiffness will be assessed non-invasively using the Mobil-O-GRAPH (I.E.M., Stolberg, Germany).
Time frame: before the exercise training
Arterial stiffness
Arterial stiffness will be assessed non-invasively using the Mobil-O-GRAPH (I.E.M., Stolberg, Germany).
Time frame: eight week
Respiratory muscle strength
Respiratory muscle strength will be evaluated using mouth pressure device
Time frame: before the exercise training
Respiratory muscle strength
Respiratory muscle strength will be evaluated using mouth pressure device
Time frame: eight week
respiratory muscle endurance
Respiratory muscle endurance will be assessed using constant load test
Time frame: before the exercise training
respiratory muscle endurance
Respiratory muscle endurance will be assessed using constant load test
Time frame: eight week
Pulmonary functions-FVC
Forced vital capacity (FVC)
Time frame: before the exercise training
Pulmonary functions-FVC
Forced vital capacity (FVC)
Time frame: eight week
Pulmonary functions-FEV1
Forced expiratory volume in the first second (FEV1)
Time frame: before the exercise training
Pulmonary functions-FEV1
Forced expiratory volume in the first second (FEV1)
Time frame: eigth week
Pulmonary functions-FEV1/FVC
FEV1/ FVC
Time frame: before the exercise training
Pulmonary functions-FEV1/FVC
FEV1/ FVC
Time frame: eight week
Pulmonary functions-FEF25-75
Forced mid-expiratory flow (FEF25-75)
Time frame: before the exercise training
Pulmonary functions-FEF25-75
Forced mid-expiratory flow (FEF25-75)
Time frame: eigth week
Peripheral muscle strength
Peripheral muscle strength will be assessed using dynamometer
Time frame: before the exercise training
Peripheral muscle strength
Peripheral muscle strength will be assessed using dynamometer
Time frame: eigth week
1 minute sit to stand test (STS) repetitions
number of sit to stand for one minute is recorded
Time frame: before the exercise training
1 minute sit to stand test (STS) repetitions
number of sit to stand for one minute is recorded
Time frame: eight week
posture
Posture will be assessed using Corbin Postural Assessment scale. Lateral and posterior views will be assessed (0 = absent,1 = mild, 2 = moderate, 3 = severe) and posture score will be determined as excellent(0-2), very good (3-4), good (5-7), fair (8-11)and poor (\>12).
Time frame: before the exercise training
posture
Posture will be assessed using Corbin Postural Assessment scale. Lateral and posterior views will be assessed (0 = absent,1 = mild, 2 = moderate, 3 = severe) and posture score will be determined as excellent(0-2), very good (3-4), good (5-7), fair (8-11)and poor (\>12).
Time frame: eigth week
Quality of life assessment
Quality of life will be assessed using the Cystic Fibrosis Questionnaire-Revised .The Cystic Fibrosis Questionnaire-Revised is a disease-specific health-related quality of life measure for children, adolescents with cystic fibrosis (CF). The questionnaire evaluate physical functioning, emotional functioning, social functioning, body image, eating disorders, treatment,respiratory symptoms and digestive symptoms. Score range is 0-100. Higher scores indicating higher health-related qualityof life.
Time frame: before the exercise training
Quality of life assessment
Quality of life will be assessed using the Cystic Fibrosis Questionnaire-Revised .The Cystic Fibrosis Questionnaire-Revised is a disease-specific health-related quality of life measure for children, adolescents with cystic fibrosis (CF). The questionnaire evaluate physical functioning, emotional functioning, social functioning, body image, eating disorders, treatment,respiratory symptoms and digestive symptoms. Score range is 0-100. Higher scores indicating higher health-related quality of life.
Time frame: eigth week
Plan to share: No
No publications or documents are linked to this record.
Started Jul 2025 (actual). Primary completion is estimated for Jul 2027, 24 months after the start.
Of 214 non-industry interventional studies with no phase under Cystic Fibrosis, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 48. This study's planned 24 months is close to that.
Counting every sponsor, half of 229 studies reached it within 23 months; a quarter within 12 and three quarters within 48.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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