ClinicalTrials.gg
RecruitingNCT07930247Updated Nov 12, 2026

Blood Pressure Control and Safety of Ex-one or Ex-one Plus in Essential Hypertension

An observational study in Essential Hypertension, sponsored by HK inno.N Corporation. Recruiting at 1 site in South Korea. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2026-11-12.

Sponsored by HK inno.N Corporation · Observational

From the registry’s dates

  • Started May 2026; still recruiting 5 months later.
Updated Nov 12, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
7,525
Ages
19 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 99 studies in Essential Hypertension with a site in Korea, Republic of — 11 open to participants now, 13 under way, 4 of them phase 3. Essential Hypertension · Korea, Republic of.

Planned enrollment
2nd of 13
7,525 · median 3,250
Started
2026
with 2 others
Observational
13 of 99
3 open now
Primary completion
2031-06
later than 12 of 12 live
Registered
99th of 99
by date
Lead sponsor
4 of 99
HK inno.N Corporation

Among the 99 studies in Essential Hypertension with a site in Korea, Republic of, this one is the 2nd largest by planned enrollment of the 13 observational ones that give a count, is one of 3 that started in 2026, is one of 13 observational ones, reaches primary completion later than 12 of the 12 other live ones, and was the 99th registered.

Essential Hypertension

479 studies on the registry are indexed under Essential Hypertension; 75 are open to participants now.

Browse Essential Hypertension studies →

Open to participants now

11 of the 99 studies in Essential Hypertension with a site in Korea, Republic of are open now. Recruiting first, the newest first:

5 more — sign in →

All 11 open studies →

A study can be open while its sites in Korea, Republic of have not opened yet or have stopped. Only those recruiting at a site in Korea, Republic of →

Who these studies take

Of the 44 Essential Hypertension studies recruiting now, 16 (36%) set no upper age limit and 20 (45%) stop at 75 or younger; 4 take children under 18; 11 take healthy volunteers.

This study: 19 Years and older · all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 99 studies in Essential Hypertension with a site in Korea, Republic of, or all of them as a file.
02

Study summary

This study aims to assess the proportion of patients with essential hypertension who achieve blood pressure control rates at Week 24 following treatment with Ex-one tablets or Ex-one Plus tablets, and to collect safety information observed during the study period.

Read the detailed description

This study aims to evaluate the efficacy of Ex-one tablets, a two-drug fixed-dose combination of amlodipine and valsartan, or Ex-one Plus tablets, a three-drug fixed-dose combination of amlodipine, valsartan, and chlorthalidone, in patients with essential hypertension in a real-world setting, focusing on the proportion of patients who achieve blood pressure control rates. In addition, safety data will be collected and evaluated in a large patient population.

03

Conditions studied

  • Essential Hypertension

Keywords

  • Ex-one
  • Ex-one Plus
  • amlodipine
  • valsartan
  • chlorthalidone
  • essential hypertension
  • blood pressure control rates
04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

University-affiliated hospitals and general hospitals where the study drug is administered

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Aged 19 years or older
  2. Patients for whom a decision has been made to administer the study medication for the treatment of essential hypertension in accordance with the approved prescribing information
  3. Patients who voluntarily provide written

Exclusion criteria

Exclusion Criteria:

  1. Patients for whom administration of the study medication is according to the approved prescribing information
  2. Patients whom the investigator considers medically unsuitable for participation in this study for reasons other than those specified above
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
7,525 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Proportion of patients achieving blood pressure control rates at Week 24 after treatment with Ex-one tablets or Ex-one Plus tablets

    Blood pressure treatment target of \<140/90 mmHg, according to the 2022 Guidelines for the Management of Hypertension issued by the Korean Society of Hypertension

    Time frame: At Week 24 after enrollment

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started May 2026 (actual). Primary completion is estimated for Jun 2031, 61 months after the start.

Of 27 observational studies under Essential Hypertension, half reached primary completion within 44 months of starting (the median), counting those still running; a quarter within 27 and three quarters within 52. This study's planned 61 months is above that.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 5, 2026
First posted
Nov 12, 2026
StartActual
May 21, 2026
Primary completionEst.
Jun 30, 2031
CompletionEst.
Jun 30, 2031
Last update
Nov 12, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 12, 2026
Show all 1 update
  1. Nov 12, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07930247
Responsible party
Sponsor
First posted
Nov 12, 2026
Start date
May 21, 2026
Primary completion
Jun 30, 2031 (estimated)
Completion
Jun 30, 2031 (estimated)
Last update
Nov 12, 2026

Study contacts

Yong-an Jeong
Contact
yongan.jeong@inno-n.com
+82-31-5176-4673
Seung Kye Cho
Contact
seungkye.cho@inno-n.com
+82-31-5176-4676

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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