An observational study in Parkinson Disease, sponsored by Federal University of Uberlandia. Recruiting at 5 sites in Brazil. Open to participants aged 18 Years to 120 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-19.
Sponsored by Federal University of Uberlandia · Observational
This is an observational, cross-sectional study with a control group, with the general objective of developing and evaluating a national database, unprecedented in Brazil, containing clinical, epidemiological, motor, and non-motor aspects of Parkinson's disease (PD). The database will be open and accessible to national and international researchers in order to contribute to the advancement of research related to PD. The aim is to collect data, in a paired way, from a control group and an experimental group. Data collection will include the application of questionnaires, the execution of motor activities, and clinical scales. Information that can identify the participants will be removed from the database for later storage in a repository. Quantitative, qualitative, and descriptive variables from the database will be estimated in order to characterise and contrast the groups studied. The results of this study will contribute to a better characterization of the staging of PD as a function of the epidemiological, motor, and non-motor aspects evaluated, as well as to the development of technologies and methods that can be applied in clinical practice.
4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.
This study's planned enrollment of 958 is above the median of 96 across 1,085 observational studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →Federal University of Uberlandia is the lead sponsor of 61 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
For both groups, individuals who have other neurological or musculoskeletal diseases that interfere with the execution of the tests will be excluded.
Group of subjects with Parkinson's disease
Neurological healthy subjects
Sex
Sex: male, female
Time frame: 10 years
Age
Age in years
Time frame: 10 years
Length of schooling
Length of schooling in years
Time frame: 10 years
Weight
Weight in kg
Time frame: 10 years
Height
Height in cm
Time frame: 10 years
Blood type
Blood type: A+, A-, B+, B-, O+, O-, AB+, AB-
Time frame: 10 years
Economic Rating Score
Economic rating as given by the Brazilian Economic Classification Criteria (Brazilian Criteria) - https://www.abep.org/criterioBr/01\_cceb\_2022\_eng.pdf
Time frame: 10 years
Primary ICD
Primary disorder classification according to the International Statistical Classification of Diseases and Related Health Problems (ICD) https://www.who.int/standards/classifications/classification-of-diseases
Time frame: 10 years
Secondary ICDs
Secondary disorder according to the International Statistical Classification of Diseases and Related Health Problems (ICD) https://www.who.int/standards/classifications/classification-of-diseases
Time frame: 10 years
Medications in use
name and daily dose of medications
Time frame: 10 years
Family history related to the primary ICD
Is there family history related to the primary ICD? (yes, no)
Time frame: 10 years
Date of symptom onset related to the primary ICD
date
Time frame: 10 years
Date of diagnosis related to the primary ICD
date
Time frame: 10 years
Current city of residence
City of residence in Brazil
Time frame: 10 years
Current state of residence
State of residence in Brazil
Time frame: 10 years
Civil status
married, single, divorced, and widowed
Time frame: 10 years
Housing classification
Housing classification by type of housing ownership rights: State-owned housing, Municipality-owned housing, Natural person's owned housing, Legal person's owned housing, Private renting, Other
Time frame: 10 years
Household size
The number of adults and children living in a home
Time frame: 10 years
Laterality
Laterality refers to the preference for using one side of the body over the other and is most commonly associated with hand dominance, such as being right-handed or left-handed, e.g., Right-handedness, Left-handedness, Ambidexterity, Mixed-handedness (Cross-dominance).
Time frame: 10 years
Use of technology
Verification if the participant has had contact with one of the following devices: mobile, personal computer, mouse, webcam, keyboard, microphone, earphone.
Time frame: 10 years
Occupation
Profession according to the Brazilian Classification of Occupation (https://www.mtecbo.gov.br/cbosite/pages/home.jsf)
Time frame: 10 years
Monthly wage
Monthly wage in Brazilian Reais
Time frame: 10 years
Head movement amplitude
Head movement amplitude in degrees
Time frame: 10 years
Head movement speed
Head movement speed in degrees per second
Time frame: 10 years
Facial expression
Facial expression evaluation according to the Facial Action Coding System (FACS)
Time frame: 10 years
Saccadic eye movement
Speed and regularity of eye movement (degrees per second and latency in ms)
Time frame: 10 years
Smooth pursuit eye movement
Smooth pursuit are quantified by the gain (how well the eyes follow the target in speed) and phase (distance to the target during pursuit)
Time frame: 10 years
Handwriting movement analysis
Handwriting speed (seconds) and quality
Time frame: 10 years
MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS)
Clinical scale for measuring signs and symptoms of Parkinson's disease (https://www.movementdisorders.org/MDS/MDS-Rating-Scales/MDS-Unified-Parkinsons-Disease-Rating-Scale-MDS-UPDRS.htm?gad\_source=1\&gclid=CjwKCAjwnqK1BhBvEiwAi7o0X6DuHrFh3qftNQ1N9AGWMkFo4BpG6b3hAFWnoh2Dwu86DPY53ZXpKRoCBRYQAvD\_BwE) Each item of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale will be evaluated as 0: Normal; 1: Slight; 2: Mild; 3: Moderate; 4: Severe. The minimum value of the scale is 0, whereas the maximum value is 4. Higher scores mean a worse outcome.
Time frame: 10 years
Depression
Depression measured according to the Geriatric Depression Scale (GDS) https://geriatrictoolkit.missouri.edu/cog/GDS\_SHORT\_FORM.PDF The Geriatric Depression Scale has 15 items. The minimum total score is zero, and the maximum is 15. Higher scores mean a worse outcome.
Time frame: 10 years
Visual Acuity
Visual Acuity measured according to the Snellen test (https://www.ncbi.nlm.nih.gov/books/NBK558961/)
Time frame: 10 years
Cognition
Cognition measured according to the Montreal Cognitive Assessment (MOCA) scale The Montreal Cognitive Assessment (MoCA) is a 30-point test. The minimum total score is zero, and the maximum is 30. Higher scores mean a better outcome.
Time frame: 10 years
Dysarthria
Dysarthria measured according to the protocol for the evaluation of central dysartries in patients with Parkinson's Disease (https://doi.org/10.1590/S1516-18462011005000030)
Time frame: 10 years
Hand movement
Hand movement in degrees per second
Time frame: 10 years
Plan to share: Yes — The data will be anonymised, stored in a safe and international plataform (Zenodo - https://github.com/NIATS-UFU). Only information that can be used to identify the subjects will be shared.
Supporting information: Study protocol, Statistical analysis plan, Analytic code
Time frame: Starting 6 months after publication
Access criteria: Researchers that wish to have access to the data can request access at https://github.com/NIATS-UFU. Full access will be granted for research purposes.
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Federal University of Uberlandia