An interventional study of Facial reanimation in patients with facial palsy without deep plane facelift. and Deep plane facelift adjunct to facial reanimation in Group 2 in Facial Palsy, sponsored by Assiut University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-02.
Sponsored by Assiut University · Not applicable, Interventional, and Treatment
Long-standing unilateral facial paralysis is a complex functional and aesthetic disorder characterized by impaired facial movement, static asymmetry, and progressive soft-tissue changes. Chronic muscular imbalance and loss of tone may result in malar descent, distortion of the nasolabial fold, oral commissure malposition, jowling, reduced mandibular definition, and asymmetric facial aging. These deformities may persist despite successful dynamic facial reanimation.
Contemporary reanimation procedures, including masseteric-to-facial nerve transfer, cross-face nerve grafting, free functional muscle transfer, and temporalis transfer, can restore facial movement and improve dynamic symmetry. However, restoration of motor function does not necessarily correct residual static soft-tissue ptosis or asymmetry. Therefore, a staged approach addressing both dynamic function and static facial contour may be beneficial.
Deep-plane facelift techniques allow repositioning of the facial soft-tissue envelope through deep-plane mobilization and release of retaining ligaments. Their application in facial paralysis has recently been explored, but limited evidence exists regarding their use as a secondary procedure following established dynamic facial reanimation.
Comprehensive outcome assessment should incorporate clinician-reported, patient-reported, and objective measures. The eFACE and Facial Clinimetric Evaluation (FaCE) Scale provide complementary assessments of facial function and patient-perceived disability, while FACE-Q instruments can evaluate aesthetic and psychosocial outcomes.
Accordingly, this prospective study evaluates deep-plane facelift as a staged adjunct after stable facial reanimation, focusing on improvement in static facial symmetry and patient-perceived appearance while maintaining previously restored dynamic facial function.
81 studies on the registry are indexed under Facial Paralysis; 28 are open to participants now.
This study's planned enrollment of 4 is below the median of 50 across 59 interventional studies indexed under Facial Paralysis.
Browse Facial Paralysis studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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1.Age ≥18 years. 2.Unilateral facial palsy (paralysis and pareses). 3.Previous first stage facial reanimation. 4.Persistent static facial asymmetry 5.Presence of at least one of the following:
Exclusion Criteria:
- 1-acute facial paralysis. 2-ongoing spontaneous neurological recovery. 3-previous extensive facelift surgery significantly altering deep-plane anatomy.
4-active facial infection. 5-uncontrolled systemic disease that substantially increases surgical risk. 6-conditions associated with impaired wound healing. 7-inability to comply with perioperative smoking cessation where required.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Facial reanimation in patients with facial palsy without deep plane facelift .
Procedure: Facial reanimation in patients with facial palsy without deep plane facelift.
Deep plane facelift adjunct to facial reanimation
Procedure: Deep plane facelift adjunct to facial reanimation in Group 2
Facial reanimation in patients with facial palsy without deep plane facelift . The exact procedure will be documented in facial reanimation , including: 1. masseteric-to-facial nerve transfer. 2. cross-face nerve graft. 3. hypoglossal-facial nerve transfer. 4. free functional muscle transfer. 5. temporalis muscle transfer. 6. combined reanimation.
Deep plane facelift adjunct to facial reanimation.
A multidimensional outcome framework will be used incorporating: 1. Clinician-reported facial function eFACE
Time frame: 6 months
Objective quantitative facial symmetry Standardized digital photography/video analysis
Time frame: 6 months
No study locations are listed for this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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