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CompletedNCT07901452Updated Oct 28, 2026

Effects of an APP Based Rehabilitation Intervention on Activities of Daily Living and Physical Performance in Patients With Post-Stroke Hemiplegia

An interventional study of limb rehabilitation app in Stroke and Hemiplegia, sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 85 Years. Per ClinicalTrials.gov, last updated 2026-10-28.

Sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 3 years 1 month after the study started (first participant enrolled Sep 2023, registered Oct 2026).
Updated Oct 28, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
46
Allocation
Non-randomized
Ages
20 Years to 85 Years
Sex
All
01

Study summary

This study aims to evaluate the effects of an AI-enabled mobile rehabilitation application combined with conventional rehabilitation on activities of daily living and physical performance among patients with post-stroke hemiplegia over a 3 month period.

Read the detailed description

A quasi-experimental study design is conducted to compare an experimental group receiving conventional rehabilitation plus an AI-enabled limb rehabilitation app with a control group receiving conventional rehabilitation alone. Participants include patients diagnosed with stroke and unilateral hemiplegia. The intervention involves 6 days per week, twice a day, focusing on upper and lower extremity exercises supported by computer-vision pose estimation and real-time feedback. Outcome measures, including the Barthel Index (BI) and the Short Physical Performance Battery (SPPB), are assessed at baseline, 1 month, and 3 months post-intervention.

02

Conditions studied

  • Stroke
  • Hemiplegia

Keywords

  • AI-enabled rehabilitation
  • Mobile application
  • Activities of daily living
  • Physical performance
03

In context

Stroke

7,476 studies on the registry are indexed under Stroke; 2,024 are open to participants now.

This study's enrollment of 46 is close to the median of 50 across 5,506 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital is the lead sponsor of 290 studies on the registry; 57 are open to participants now.

Browse Kaohsiung Medical University Chung-Ho Memorial Hospital studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Diagnosed with stroke and unilateral hemiplegia.
  2. Aged between 20 and 85 years.
  3. Possesses a smartphone or tablet.

Exclusion criteria

Exclusion Criteria :

  1. Clinically unstable condition preventing participation.
  2. Concurrently enrolled in other interventional studies.
  3. Diagnosed with dementia.
  4. Unable to operate a smartphone.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
46 participants (actual)

Study arms

  • Experimental
    Experimental Group

    Receiving routine rehabilitation combined with an upper limb rehabilitation app intervention.

    Device: limb rehabilitation app

  • Active comparator
    Usual Care Group

    Receiving routine rehabilitation only.

    Device: limb rehabilitation app

Interventions

  • Devicelimb rehabilitation app

    An application designed for limb rehabilitation training, used by patients with post-stroke hemiplegia for guided exercises.

06

What researchers measure

Primary outcomes

  1. Barthel Index (BI) and Short Physical Performance Battery (SPPB)

    Evaluation of activities of daily living using the Barthel Index and physical performance using the Short Physical Performance Battery (SPPB).

    Time frame: Baseline, 1 month, and 3 months post-intervention

07

Study locations

1 site
  • Kaohsiung Medical University Chung-Ho Memorial Hospital
    Kaohsiung City, Taiwan (r.o.c.) 807063, Taiwan
08

References and documents

Publications

  • Cirstea, M. C., & Levin, M. F. (2000). Compensatory strategies for reaching in stroke. Brain, 123(5), 940-953. Do, Y., Lim, Y., Jin, S., & Lee, H. (2025). Effectiveness of home-based rehabilitation on activities of daily living in patients with stroke: Systematic review and meta-analysis. Physical Therapy, 105(6), pzaf044. Gómez, J. F., Curcio, C. L., Alvarado, B., Zunzunegui, M. V., & Guralnik, J. (2013). Validity and reliability of the Short Physical Performance Battery (SPPB): A pilot study on mobility in the Colombian Andes. Colombia Médica, 44(3), 165-171. Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994). A Short Physical Performance Battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. Journal of Gerontology, 49(2), M85-M94. Hsueh, I.-P., Lin, J.-H., Jeng, J.-S., & Hsieh, C.-L. (2002). Comparison of the psychometric characteristics of the Functional Independence Measure, 5-item Barthel Index, and 10-item Barthel Index in patients with stroke. Journal of Neurology, Neurosurgery & Psychiatry, 73(2), 188-190. Kopalli et al. (2025) - Artificial intelligence in stroke rehabilitation: From acute care to long-term recovery. Neuroscience, 572, 214-231. Mahmoud, H., Aljaldi, F., El-Fiky, A., Battecha, K., Thabet, A., Alayat, M., Abd Elkafy, E., Ebid, A., & Ibrahim, A. (2023). Artificial intelligence machine learning and conventional physical therapy for upper limb outcome in patients with stroke: A systematic review and meta-analysis. European Review for Medical and Pharmacological Sciences, 27(11), 4812-4827.

Individual participant data

Plan to share: No — The data are currently under statistical analysis and have not yet been published.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Sep 2023 to primary completion in Jun 2025, 21 months.

Of 2,877 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 45. This study's 21 months is close to that.

Counting every sponsor, half of 3,006 studies reached it within 23 months; a quarter within 10 and three quarters within 45.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 17, 2026
First posted
Oct 28, 2026
StartActual
Sep 13, 2023
Primary completionActual
Jun 20, 2025
CompletionActual
Jun 20, 2025
Last update
Oct 28, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 28, 2026
Show all 1 update
  1. Oct 28, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07901452
Lead sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Responsible party
KMUHIRB-E(II)-20220242 (NURSE, Kaohsiung Medical University Chung-Ho Memorial Hospital) — Principal investigator
First posted
Oct 28, 2026
Start date
Sep 13, 2023
Primary completion
Jun 20, 2025
Completion
Jun 20, 2025
Last update
Oct 28, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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