An observational study in MRI in Evaluation of Fecal Incontinence, sponsored by Assiut University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by Assiut University · Observational
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool. It represents a significant clinical challengewithsubstantial impacts on patient quality of life.The severity and clinical impact of fecal incontinenceare standardized using the Jorge-Wexner Incontinence Score, a widely validatedsymptomscoring instrument. The Wexner score assesses five key domains: loss of solid stool, liquidstool, and flatus, as well as the need to wear protective pads and the degree of lifestyle alteration. Eachparameter is graded on a scale from 0 (Never) to 4 (Always), yielding a composite scorerangingfrom 0 (perfect continence) to 20 (complete incontinence). * 1-8: Mild incontinence * 9-14: Moderate incontinence * 15-20: Severeincontinence
Establishing an objective clinical baseline via the Wexner score is crucial for stratifyingpatients, correlating structural sphincter defects visualized on imaging with functional clinical impairment,and selecting candidates who will benefit most from anatomical surgical repair[1].Preciseanatomical and functional evaluation of the pelvic floor musculature-specifically theinternal analsphincter (IAS) and external anal sphincter (EAS)-is paramount to selecting appropriatetherapeutic interventions, whether conservative or surgical [2]. Currently, two primary imaging modalities dominate the diagnostic workup of FI: Three-Dimensional Endoanal Ultrasound (3D-EAUS) and External Phased Array Magnetic ResonanceImaging (MRI) [3]. 3D-EAUS has long been regarded as a practical, high-resolutionparadigmforidentifying localized sphincter tears and defects due to its accessibility and superior depictionofthe thin muscular layers. However, its accuracy can be highly operator-dependent, andit provideslimited visualization of complex, deep pelvic floor disorders or external atrophy [4]. Conversely, external phased array MRI offers a wider field of view, exceptional soft-tissuecontrast,and optimal evaluation of sphincter atrophy, scarring, and secondary pelvic organprolapsewithout the discomfort associated with endorectal coils [5]. Despite their integrationintoclinicalpractice, substantial ambiguity persists regarding which modality yields higher precisediagnosticaccuracy for varying severities of structural defects, and how they directly comparewhenoptimizing preoperative strategies [3, 5]. This study aims to establish an optimizeddiagnosticparadigm, helping clinicians select the most efficient imaging modality or integratedapproachtoimprove patient outcomes at Assiut University Hospitals.
283 studies on the registry are indexed under Fecal Incontinence; 52 are open to participants now.
This study's planned enrollment of 22 is below the median of 92 across 66 observational studies indexed under Fecal Incontinence.
Browse Fecal Incontinence studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Patients presenting to the Outpatient Clinics of General/Colorectal Surgery and referred to the Radiology Department with clinical symptoms of fecal incontinence.
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Patients with clinically documented fecal incontinence with a Jorge-Wexner Incontinence Score ≥ 1 (indicative of mild-to-severe clinical symptoms warranting anatomical imaging and potential surgical repair).
Patients referred for anatomical mapping prior to surgical repair.
Exclusion Criteria:
Patients with absolute to MRI (e.g., cardiac pacemakers, metallic implants, severe claustrophobia).
Previous major colorectal or oncological pelvic surgery that drastically alters the local anatomy.
Active perianal sepsis, acute anal fissures, or severe painful perianal conditions preventing probe insertion for EAUS.
Known or suspected pelvic/anorectal : Patients with active pelvic, colorectal, or gynecological malignancies
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Device: 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
) Toevaluate the diagnostic agreement and correlation between 3D endoanal ultrasound (3D-EAUS) and external phased array MRI in identifying and grading the extent of internal and external anal sphincter defects in patients presenting with fecal incontinence.
Toevaluate the diagnostic agreement and correlation between 3D endoanal ultrasound (3D-EAUS) and external phased array MRI
Time frame: one year
No study locations are listed for this record.
Plan to share: Yes
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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