An interventional study of Traditional Exposure and Response Prevention (ERP) and Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET) in Obsessive Compulsive Disorder (OCD), sponsored by University of California, San Diego. Not yet recruiting. Open to participants aged 18 Years to 29 Years. Per ClinicalTrials.gov, last updated 2026-10-16.
Sponsored by University of California, San Diego · Not applicable, Interventional, and Treatment
This research study is being conducted to study the use of artificial-intelligence powered virtual reality exposure therapy (AI-VRET) to treat college students with obsessive compulsive disorder (OCD).
626 studies on the registry are indexed under Obsessive-Compulsive Disorder; 162 are open to participants now.
This study's planned enrollment of 24 is below the median of 45 across 510 interventional studies indexed under Obsessive-Compulsive Disorder.
Browse Obsessive-Compulsive Disorder studies →University of California, San Diego is the lead sponsor of 975 studies on the registry; 196 are open to participants now.
Of its 111 completed or terminated interventional studies of FDA-regulated products, 71 (64%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Exposure and response prevention (ERP) is a specific type of cognitive behavioral therapy (CBT) that is the most effective, and first-line psychotherapy for children, adolescents, and adults. ERP is guided by a trained therapist and helps individuals extinguish fears and reduce or eliminate compulsive behaviors in a structured and supportive environment. ERP treatment begins by the therapist providing the patient with psychoeducation and then developing an exposure hierarchy or exposure list for the individual's OCD symptoms. The individual with OCD is then exposed to stimuli that elicit distress (exposure) and then prevented from engaging in compulsive, ritualistic, or avoidance behavior (response prevention). The exact ERP session varies depending on the individual's OCD symptoms and their readiness to engage in compulsions. The therapist and patient then collaboratively develop practice or homework assignments to complete between sessions.
Other: Traditional Exposure and Response Prevention (ERP)
Virtual reality exposure therapy is a modality of exposure therapy that immerses individuals in computer-generated scenarios to gradually face their fears while wearing headsets that place them in the immersive environments. Artificial intelligence-powered virtual reality exposure therapy (AI-VRET), adds on to virtual reality exposure therapy by enabling the therapist to modify the virtual reality environment by use of artificial intelligence in real-time.
Device: Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET)
Exposure and response prevention (ERP) is a specific type of cognitive behavioral therapy (CBT) that is the most effective, and first-line psychotherapy for children, adolescents, and adults. ERP is guided by a trained therapist and helps individuals extinguish fears and reduce or eliminate compulsive behaviors in a structured and supportive environment. ERP treatment begins by the therapist providing the patient with psychoeducation and then developing an exposure hierarchy or exposure list for the individual's OCD symptoms. The individual with OCD is then exposed to stimuli that elicit distress (exposure) and then prevented from engaging in compulsive, ritualistic, or avoidance behavior (response prevention). The exact ERP session varies depending on the individual's OCD symptoms and their readiness to engage in compulsions. The therapist and patient then collaboratively develop practice or homework assignments to complete between sessions.
Virtual reality exposure therapy is a modality of exposure therapy that immerses individuals in computer-generated scenarios to gradually face their fears while wearing headsets that place them in the immersive environments. Artificial intelligence-powered virtual reality exposure therapy (AI-VRET), adds on to virtual reality exposure therapy by enabling the therapist to modify the virtual reality environment by use of artificial intelligence in real-time.
Yale-Brown Obsessive Compulsive Scale-II (Y-BOCS-II)
Time frame: Visits 1 (baseline) & 14 (post-treatment assessment, approximately 14 weeks following baseline)
Florida Obsessive-Compulsive Inventory (FOCI)
Time frame: Visits 1 (baseline) & 14 (post-treatment assessment, approximately 14 weeks following baseline)
Adult OCD Impact Scale (OCD-IS):
Time frame: Visits 1 (baseline) & 14 (post-treatment assessment, approximately 14 weeks following baseline)
Sheehan Disability Scale (SDS)
Time frame: Visits 1 (baseline) & 14 (post-treatment assessment, approximately 14 weeks following baseline)
Generalized Anxiety Disorder-7 (GAD-7):
Time frame: Visits 1-14 (all study visits). Visit 1 is at baseline, and subsequent visits are approximately one week apart. The final visit is approximately 14 weeks after baseline.
Patient Health Questionnaire-9 (PHQ-9)
Time frame: Visits 1-14 (all study visits). Visit 1 is at baseline, and subsequent visits are approximately one week apart. The final visit is approximately 14 weeks after baseline.
Presence Questionnaire (PQ)
Time frame: Visits 2-13. Visit 2 is approximately one week following baseline, and subsequent visits are approximately one week apart. Visit 13 is approximately 13 weeks following baseline.
Cybersickness in Virtual Reality Questionnaire (CSQ-VR)
Time frame: Visits 2-13. Visit 2 is approximately one week following baseline, and subsequent visits are approximately one week apart. Visit 13 is approximately 13 weeks following baseline.
No study locations are listed for this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Obsessive-Compulsive Disorder →
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