An interventional study of Standard physical therapy and Neuromuscular Facilitation Protocol in Knee Osteoarthristis, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 40 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-10-13.
Sponsored by Riphah International University · Not applicable, Interventional, and Treatment
An individual can suffer from knee osteoarthritis, which is a degenerative condition, and while standard physical therapy can assist in some way, improved joint mechanics and decreased functional limitations can be achieved through the use of specialized methods, such as the advanced protocols of Neuromuscular Facilitation. Objective of this study is to use Neuromuscular Facilitation, a technique to investigate in terms of its effect in comparison to standard Physical therapy on the levels of pain, the range and range of motion at the joint, and the overall physical disability associated with knee osteoarthritis. An experiment that involved a randomized group of 54 subjects who were aged between 40 and 80 with Grade 2 or 3 knee osteoarthritis was conducted. Recruitment of subjects was done by way of non-probability convenience sampling at United Hospital in Faisalabad. Subjects were randomly placed in 2 groups: PNF-based neuromuscular facilitation group (Group A) received bridging, side decubits, sural triceps, sitting and standing from chair, lateral walk, going up and down stairs, squating and group B received standard Physical therapy which included cryotherapy and isometric Quadriceps strengthening and Isometric Hip adductor strengthening exercise. The outcomes were assessed using Numeric Pain Rating Scale, Goniometry for range of motion, and The Western Ontario and McMaster Universities Osteoarthritis Index.
3,391 studies on the registry are indexed under Osteoarthritis, Knee; 628 are open to participants now.
This study's enrollment of 54 is below the median of 69 across 2,808 interventional studies indexed under Osteoarthritis, Knee.
Browse Osteoarthritis, Knee studies →Riphah International University is the lead sponsor of 2,176 studies on the registry; 637 are open to participants now.
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Standard Physical therapy included Cryotherapy ,Isometric Quadriceps Strengthening Exercise, and Isometric Hip Adductor Strengthening Exercise.
Other: Standard physical therapy
Neuromuscular Facilitation Rehabilitation that works on PNF principal and help in strengthening of lower limbs with the help of exercise Which include bridge, side Decubitus, sural triceps, sitting and standing from chair, lateral walk, going up and down stairs and squatting.
Other: Neuromuscular Facilitation Protocol
Standard physical therapy include Cryotherapy. That was placed on the anterior side of knee joint for 10 mintues, Isometric Quadriceps Strengthening Exercises, and Isometric Hip Adductor Strengthening Exercises. Both for Two sets of 10 repetitions.
Patients received Neuromuscular Facilitation Rehabilitation that works on PNF principal and help in strengthening of lower limbs with the help of exercise. It included bridging exercise , side Decubitus, sural triceps, sitting and standing from chair. lateral walk, going up and down stairs, squatting. All these exercises have sessions two through four that worked on combination of isotonic methods. In fiirst and second weeks two sets of three repeats, in weeks three and four two sets of four repetitions.
WOMAC index for disability
Originally validated by Dr. Nicholas Bellamy in 1988, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a disease-specific, to assess the effectiveness of treatment in patients with knee osteoarthritis. The test comprises 24 unique items that are separated into three separate functional subscales: a 17-item Physical Function domain that measures limitations during activities of daily living (ADLs), a 2-item Stiffness domain that evaluates joint restriction during waking or rest, and a 5-item Pain domain that measures mechanical discomfort during essential activities like walking or stair negotiation. The standard 5-point Likert version rates each item from 0 (None) to 4 (Extreme). This results in cumulative subscale limits of 0-20 for pain, 0-8 for stiffness, and 0-68 for physical function, which add up to a global composite score that ranges from 0 to 96, with higher values denoting more severe structural and functional degeneration.
Time frame: 4th day
NPRS for pain score
The NPRS is a frequently used tool for evaluating the severity of pain at a particular moment, by asking individuals to rate their discomfort on a scale value from 0 to 10, in which 0 indicates "there is no pain" and 10 indicating "very painful". In many clinical practices, the NPRS is routinely used during outpatient visits, and these scores are documented in the patient's electronic health record (EHR) to enable ongoing monitoring of pain intensity by both clinicians and researchers.
Time frame: 4th weeks
Universal Goniometer (UG) for ROM
ROM is an important parameter for evaluation of movement limitations. While clinicians researchers use universal goniometers to measure ROM, the accuracy of the method depends on the clinician's skill and experience. The normal Knee Flexion range of motion is Stairs, chairs, and slopes that need less than 90 degrees of knee flexion 90-120 degrees and roughly 135 degrees of knee flexion in a bath
Time frame: 4th Weeks
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2026 to primary completion in Mar 2026, 2 months.
Of 1,143 non-industry interventional studies with no phase under Osteoarthritis, Knee, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 36. This study's 2 months is below that.
Counting every sponsor, half of 1,285 studies reached it within 18 months; a quarter within 8 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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