An interventional study of Self-Titration in Hypertension, sponsored by Brigham and Women's Hospital. Not yet recruiting at 1 site in United States. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2026-10-13.
Sponsored by Brigham and Women's Hospital · Not applicable, Interventional, and Health services research
The objective of this study is to pilot test self-titration intervention procedures. We are testing a new way to manage high blood pressure from home. In this study, patients will check their blood pressure at home and take steps to adjust their blood pressure medications if needed, following a plan outlined with a primary care doctor. Participation in this study will last up to 6 months.
Participation will include a research visit to review the blood pressure management process. A primary care provider will also develop a medication plan for each participant to follow during the study and address any questions at their upcoming visit. During the study, each participant will be asked to check their blood pressure at home every day for 1-2 weeks a month using a study-provided blood pressure cuff. They will be asked to follow a set of instructions to request a medication change from their provider, based on their blood pressure readings. Participation may also include lab visits and additional visits with a primary care physician before making medication changes, if needed. There will also be a follow-up visit within 6 months.
6,834 studies on the registry are indexed under Hypertension; 971 are open to participants now.
This study's planned enrollment of 30 is below the median of 90 across 5,095 interventional studies indexed under Hypertension.
Browse Hypertension studies →Brigham and Women's Hospital is the lead sponsor of 1,263 studies on the registry; 225 are open to participants now.
Of its 116 completed or terminated interventional studies of FDA-regulated products, 65 (56%) have results posted.
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Exclusion Criteria:
Other: Self-Titration
Following consent, patients will complete a brief baseline questionnaire, including questions about blood pressure knowledge. Staff will ensure that the patient has a validated BP cuff for home use, teach them how to use it, calibrate the cuff, and test entering values. Patients will proceed through the self-titration process for 6 months.
Change in BP (blood pressure)
Change in BP between baseline and 6 months in intervention vs. usual care
Time frame: 180 days
Healthcare Utilization
Outpatient visits, ED visits, hospitalizations, portal messages, phone calls
Time frame: 180 days
Side Effects and Adverse Events
Common side effects and adverse events
Time frame: 180 days
BP Knowledge
Hypertension knowledge scale
Time frame: 180 days
Plan to share: Yes — De-identified study data
Supporting information: Statistical analysis plan, Informed consent form
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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