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CompletedNCT07869667Updated Oct 9, 2026

NEURO-MODULATORY EFFECT OF ELECTRO-ACUPUNCTURE ON COMPLEX REGIONAL PAIN SYNDROME IN POST STROKE PATIENTS

An interventional study of Electroacupuncture and Conventional physical therapy program in Stroke, sponsored by Ahmed Alshimy. Completed at 1 site in Egypt. Open to participants aged 45 Years and older. Per ClinicalTrials.gov, last updated 2026-10-09.

Sponsored by Ahmed Alshimy · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Jan 2026, registered Oct 2026).
Updated Oct 9, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
45 Years and older
Sex
All
01

Study summary

Improvement in pain and range of motion (ROM) outcomes for stroke cases suffering from complex regional pain syndrome (CRPS) can be attained through Electro-acupuncture therapy, which in turn improve functional independence and reduces financial strain on both patients and their families.

Read the detailed description

Group A received three sessions weekly of selected physical therapy program and electroacupuncture therapy, while Group B received the same selected physical therapy program alone. The Visual Analogue Scale (VAS) was used to assess pain, the Kinovea-based measurement was used to evaluate shoulder flexion ROM; and the Disabilities of the Arm, Shoulder, and Hand questionnaire (DASH)-Arabic version was used to assess functional independence.

02

Conditions studied

  • Stroke

Keywords

  • Stroke
  • Complex Regional Pain Syndrome
  • Electro-acupuncture
03

In context

Stroke

7,441 studies on the registry are indexed under Stroke; 2,012 are open to participants now.

This study's enrollment of 40 is below the median of 50 across 5,482 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Ahmed Alshimy is the lead sponsor of 10 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • The patients were diagnosed clinically and referred from a neurologist
  • The study included cases who were 45 years old or more
  • Ischemic stroke at least six months following the stroke, were receiving treatment at the outpatient clinic, and demonstrated satisfactory cognitive function (Montreal Cognitive Assessment score of more than 26), spasticity of the limbs ranging from grade 1+ (2) on a modified Ashworth scale, and a confirmed diagnosis of CRPS by clinical assessment by a neurologist using the Budapest criteria for diagnosis of CRPS.
  • Unilateral upper-limb or shoulder pain persisting for at least four weeks and up to six months following the onset of stroke. Pain intensity rated ≥ 4/10 on the Visual Analogue Scale (VAS) at rest or with active/passive shoulder movement.

Exclusion criteria

Exclusion Criteria:

  • Patients with current history of hand troubles and shoulder dysfunction before developing a stroke.
  • Patients with overactive sympathetic system from other causes e.g. congestive heart failure, impaired kidney functions.
  • Patients with significant musculoskeletal disorders which include rheumatoid arthritis or metabolic disorders comprising diabetes, Patients with cognitive impairments, Visual, auditory and speech problems and Patients with psychiatric disorders or seizures.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Factorial assignment
Masking
Double (Participant, Investigator)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Group A

    Consisted of 20 patients who received a selected physical therapy program and electroacupuncture. The treatment was conducted for four weeks, three sessions weekly for 12 sessions

    Other: Electroacupuncture · Other: Conventional physical therapy program

  • Experimental
    Group B

    Consisted of 20 cases who received the same selected physical therapy program only, for four weeks, three sessions weekly for 12 sessions.

    Other: Conventional physical therapy program

Interventions

  • OtherElectroacupuncture

    Sterile, single-use stainless-steel acupuncture needles (0.25 × 30 mm) were inserted at six acupoints on the affected side: TE14., SI9., and GB21(shoulder region); LI11 and TE5 (elbow and forearm); and TE2 (dorsum of the hand)

  • OtherConventional physical therapy program

    (1) passive and active-assisted range of motion exercises (5-10 repetitions per movement, 10-15 second holds) (2) desensitization techniques using graded textures (cotton, sponge, Velcro, toothbrush), progressing from light touch to deep pressure, combined with contrast baths (3) therapeutic exercises, beginning with isometric strengthening and progressing to isotonic exercises as tolerated, followed by functional task-based activities targeting coordination and strength; (4) a structured stress-loading program involving active movement and joint compression, including quadruped scrubbing with the affected hand (5) heat therapy using hot packs for pain relief and (6) graded motor imagery, progressing through laterality training, explicit motor imagery, and mirror visual feedback. Each session began with a 5-minute warm-up and ended with a 5-minute cool-down.

06

What researchers measure

Primary outcomes

  1. Visual analogue scale

    Subjective pain assessment

    Time frame: 4 weeks

  2. Kinovea-based measurement for shoulder flexion

    Shoulder flexion range of motion (ROM) assessment was conducted using Kinovea-2020 software following a standardized protocol

    Time frame: 4 weeks

  3. Arabic version of DASH questionnaire

    Designed to quantify functional limitations and symptoms affecting the arm, shoulder, and hand region

    Time frame: 4 weeks

07

Study locations

1 site
  • Al Ryada University for Science and Technology
    Sadat, Menoufia, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 9, 2026
Show all 1 update
  1. Oct 9, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07869667
Lead sponsor
Ahmed Alshimy
Responsible party
Ahmed Alshimy (Lecturer of Physical Therapy for Neurology and its Surgery Faculty of Physical Therapy - Al Ryada University for Science and Technology, AlRyada University for Science & Technology) — Sponsor-investigator
First posted
Oct 9, 2026
Start date
Jan 5, 2026
Primary completion
Jul 12, 2026
Completion
Aug 24, 2026
Last update
Oct 9, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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